Sfoglia per Autore LADU, SARA
Chromosome mapping of multiple loci affecting the genetic predisposition to rat liver carcinogenesis.
2002-01-01 De Miglio, Mr; Pascale, Rm; Simile, Mm; Muroni, Mr; Calvisi, Df; Virdis, P; Bosinco, Gm; Frau, M; Seddaiu, Ma; Ladu, Sara; Feo, F.
Disruption of beta-catenin pathway or genomic instability define two distinct categories of liver cancer in transgenic mice.
2004-01-01 Calvisi, Df; Factor, Vm; Ladu, Sara; Conner, Ea; Thorgeirsson, S. S.
Vitamin E down-modulates iNOS and NADPH oxidase in c-Myc/TGF-alpha transgenic mouse model of liver cancer.
2004-01-01 Calvisi, Df; Ladu, Sara; Hironaka, K; Factor, Vm; Thorgeirsson, S. S.
Disregulation of E-cadherin in transgenic mouse models of liver cancer.
2004-01-01 Calvisi, Df; Ladu, Sara; Conner, Ea; Factor, Vm; Thorgeirsson, S. S.
Activation of beta-catenin provides proliferative and invasive advantages in c-myc/TGF-alpha hepatocarcinogenesis promoted by phenobarbital.
2004-01-01 Calvisi, Df; Ladu, Sara; Factor, Vm; Thorgeirsson, S. S.
Activation of the canonical Wnt/beta-catenin pathway confers growth advantages in c-Myc/E2F1 transgenic mouse model of liver cancer.
2005-01-01 Calvisi, Df; Conner, Ea; Ladu, Sara; Lemmer, Er; Factor, Vm; Thorgeirsson, Ss
Ubiquitous activation of Ras and Jak/Stat pathways in human HCC.
2006-01-01 Calvisi, Df; Ladu, Sara; Gorden, A; Farina, M; Conner, Ea; Lee, Js; Factor, Vm; Thorgeirsson, S. S.
Mechanistic and prognostic significance of aberrant methylation in the molecular pathogenesis of human hepatocellular carcinoma.
2007-01-01 Calvisi, Df; Ladu, Sara; Gorden, A; Farina, M; Lee, Js; Conner, Ea; Schroeder, I; Factor, Vm; Thorgeirsson, S. S.
Altered methionine metabolism and global DNA methylation in liver cancer: relationship with genomic instability and prognosis.
2007-01-01 Calvisi, Df; Simile, Mm; Ladu, Sara; Pellegrino, R; De Murtas, V; Pinna, F; Tomasi, Ml; Frau, M; Virdis, P; De Miglio, Mr; Muroni, Mr; Pascale, Rm; Feo, F.
E2F1 inhibits c-Myc-driven apoptosis via PIK3CA/Akt/mTOR and COX-2 in a mouse model of human liver cancer.
2008-01-01 Ladu, Sara; Calvisi, Df; Conner, Ea; Farina, M; Factor, Vm; Thorgeirsson, Ss
Dual-specificity phosphatase 1 ubiquitination in extracellular signal-regulated kinase-mediated control of growth in human hepatocellular carcinoma.
2008-01-01 Calvisi, Df; Pinna, F; Meloni, F; Ladu, Sara; Pellegrino, R; Sini, M; Daino, L; Simile, Mm; De Miglio, Mr; Virdis, P; Frau, M; Tomasi, Ml; Seddaiu, Ma; Muroni, Mr; Feo, F; Pascale, Rm
Aberrant iNOS signaling is under genetic control in rodent liver cancer and potentially prognostic for the human disease.
2008-01-01 Calvisi, Df; Pinna, F; Ladu, Sara; Pellegrino, R; Muroni, Mr; Simile, Mm; Frau, M; Tomasi, Ml; De Miglio, Mr; Seddaiu, Ma; Daino, L; Sanna, V; Feo, F; Pascale, Rm
SKP2 and CKS1 promote degradation of cell cycle regulators and are associated with hepatocellular carcinoma prognosis.
2009-01-01 Calvisi, Df; Ladu, Sara; Pinna, F; Frau, M; Tomasi, Ml; Sini, M; Simile, Mm; Bonelli, P; Muroni, Mr; Seddaiu, Ma; Lim, Ds; Feo, F; Pascale, R. M.
Forkhead box M1B is a determinant of rat susceptibility to hepatocarcinogenesis and sustains ERK activity in human HCC.
2009-01-01 Calvisi, Df; Pinna, F; Ladu, Sara; Pellegrino, R; Simile, Mm; Frau, M; De Miglio, Mr; Tomasi, Ml; Sanna, V; Muroni, Mr; Feo, F; Pascale, Rm
The degradation of cell cycle regulators by SKP2/CKS1 ubiquitin ligase is genetically controlled in rodent liver cancer and contributes to determine the susceptibility to the disease.
2010-01-01 Calvisi, Df; Pinna, F; Ladu, Sara; Muroni, Mr; Frau, M; Demartis, I; Tomasi, Ml; Sini, M; Simile, Mm; Seddaiu, Ma; Feo, F; Pascale, R. M.
Synergistic role of Sprouty2 inactivation and c-Met up-regulation in mouse and human hepatocarcinogenesis.
2010-01-01 Lee, Sa; Ladu, Sara; Evert, M; Dombrowski, F; De Murtas, V; Chen, X; Calvisi, D. F.
Oncogenic and tumor suppressive roles of Polo-like kinases in human hepatocellular carcinoma (p NA).
2010-01-01 Pellegrino, R.; Calvisi, D. F.; Ladu, Sara; Ehemann, V; Staniscia, Tommaso; Evert, M; Dombrowski, F; Schirmacher, P; Longerich, T.
Downregulation of PH domain leucine-rich repeat protein phosphatases (PHLPPs) identifies a subgroup of human hepatocellular and colorectal carcinomas with elevated levels of activated AKT and low apoptosis rate
2011-01-01 Ladu, Sara; Staniscia, Tommaso; Raffaella, M. D.; Giuseppe, B; Romano, Ferdinando; Calvisi, D.
Mybl2 expression is under genetic control and contributes to determine a hepatocellular carcinoma susceptible phenotype.
2011-01-01 Frau, M; Ladu, Sara; Calvisi, Df; Simile, Mm; Bonelli, P; Daino, L; Tomasi, Ml; Seddaiu, Ma; Feo, F; Pascale, R. M.
AKT (v-akt murine thymoma viral oncogene homolog 1) and N-Ras (neuroblastoma ras viral oncogene homolog) coactivation in the mouse liver promotes rapid carcinogenesis by way of mTOR (mammalian target of rapamycin complex 1), FOXM1 (forkhead box M1)/SKP2, and c-Myc pathways.
2011-01-01 Ho, C; Wang, C; Mattu, S; Destefanis, G; Ladu, Sara; Delogu, S; Armbruster, J; Fan, L; Lee, Sa; Jiang, L; Dombrowski, F; Evert, M; Chen, X; Calvisi, D. F.
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