The use of the biocompatible amphiphilic diblock copolymer poly(ethylene glycol-b-propylene sulfide) (PEG44PPS20) allows a tuned loading of doxorubicin onto the surface of non-functionalized multiwalled carbon nanotubes and an efficient cell internalization. The obtained multi-walled carbon nanotube-based systems show enhanced cytotoxic activity with respect to non-vehicled doxorubicin.
Biocompatible dispersions of carbon nanotubes: a potential tool for intracellular transport of anticancer drugs
DI CRESCENZO, ANTONELLO;FONTANA, Antonella
2011-01-01
Abstract
The use of the biocompatible amphiphilic diblock copolymer poly(ethylene glycol-b-propylene sulfide) (PEG44PPS20) allows a tuned loading of doxorubicin onto the surface of non-functionalized multiwalled carbon nanotubes and an efficient cell internalization. The obtained multi-walled carbon nanotube-based systems show enhanced cytotoxic activity with respect to non-vehicled doxorubicin.File in questo prodotto:
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