The present invention relates on an ex vivo method for the analysis, enumeration and/or classification and/or isolation of microvesicles present in whole biological fluid samples, in particular by flow cytometry
The present invention relates to a special type of non-internalizing binding moiety- drug-conjugates that specifically target LGALS3BP. From one aspect, the invention relates to an antibody-drug-conjugate comprising an antibody capable of binding to LGALS3BP, said antibody being conjugated to cytotoxic drugs. The invention also comprises methods of the treatment of LGALS3BP-expressing cancer, including administering to a patient the disclosed drug conjugates and pharmaceutical preparations.
Mouthpiece of diving regulator of aqualung and/ or snorkel comprising a tubular connection portion (2) wherein said tubular connection portion has a through hole (3) internally engaged at a distal portion (4) with a complementary tubular portion of said aqualung and/ or snorkel to allow the air passage; and a bite (5) connected to said tubular connection portion at the lower edge (6) of the proximal end (7) extending complete arch acting as a support for a dental arch.