PurposeTo determine the true incidence of associated intestinal atresia (AIA) in infants with duodenal atresia (DA) and to analyze whether the surgical approach, open versus laparoscopic, would impact on patient outcome when AIA is present.MethodsCohort study We review all DA infants treated at our institution (2001-2016) and analyzed the outcome of those with AIA. Systematic review/meta-analysis Using a defined search strategy and according to PRISMA guidelines, two investigators independently identified all studies on DA and searched cases of AIA to determine its incidence. Data are meanSD.ResultsCohort study Of 140 DA infants, 10 (7%) had AIA (4 type I, 4 type III, 2 type II). All type I AIA (webs) were found in the duodenum. Systematic review/meta-analysis Of 840 studies, 18 were included (2026 infants). The incidence of AIA was 2.8 +/- 1.6%. The incidence of missed AIA was 0.8 +/- 2.4%. Three comparative studies (759 infants) showed higher risk of missed AIA following laparoscopic (2.9 +/- 2.4%) than open repair (0.3 +/- 0.1%; p<0.01).Conclusions p id=Par4 The incidence of AIA in DA infants is low and the risk of missing it is higher at laparoscopy than at laparotomy. Regardless the approach, surgeons should carefully investigate bowel continuity to avoid the risk of missing AIA.

Duodenal atresia and associated intestinal atresia: a cohort study and review of the literature

Miscia, Maria Enrica
Primo
;
Lauriti, Giuseppe
Secondo
;
Lelli Chiesa, Pierluigi
Penultimo
;
2019-01-01

Abstract

PurposeTo determine the true incidence of associated intestinal atresia (AIA) in infants with duodenal atresia (DA) and to analyze whether the surgical approach, open versus laparoscopic, would impact on patient outcome when AIA is present.MethodsCohort study We review all DA infants treated at our institution (2001-2016) and analyzed the outcome of those with AIA. Systematic review/meta-analysis Using a defined search strategy and according to PRISMA guidelines, two investigators independently identified all studies on DA and searched cases of AIA to determine its incidence. Data are meanSD.ResultsCohort study Of 140 DA infants, 10 (7%) had AIA (4 type I, 4 type III, 2 type II). All type I AIA (webs) were found in the duodenum. Systematic review/meta-analysis Of 840 studies, 18 were included (2026 infants). The incidence of AIA was 2.8 +/- 1.6%. The incidence of missed AIA was 0.8 +/- 2.4%. Three comparative studies (759 infants) showed higher risk of missed AIA following laparoscopic (2.9 +/- 2.4%) than open repair (0.3 +/- 0.1%; p<0.01).Conclusions p id=Par4 The incidence of AIA in DA infants is low and the risk of missing it is higher at laparoscopy than at laparotomy. Regardless the approach, surgeons should carefully investigate bowel continuity to avoid the risk of missing AIA.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11564/701745
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