Whole brain 31P MRSI at 7T with a dual-tuned receive array

Purpose: The design and performance of a novel head coil setup for (Formula presented.) P spectroscopy at ultra-high field strengths (7T) is presented. The described system supports measurements at both the (Formula presented.) H and (Formula presented.) P resonance frequencies. Methods: The novel coil consists of 2, actively detunable, coaxial birdcage coils to give homogeneous transmit, combined with a double resonant 30 channel receive array. This allows for anatomical imaging combined with (Formula presented.) P acquisitions over the whole head, without changing coils or disturbing the subject. A phosphate buffer phantom and 3 healthy volunteers were scanned with a pulse acquire CSI sequence using both the novel array coil and a conventional transceiver birdcage. Four different methods of combining the array channels were compared at 3 different levels of SNR. Results: The novel coil setup delivers significantly increased (Formula presented.) P SNR in the peripheral regions of the brain, reaching up to factor 8, while maintaining comparable performance relative to the birdcage in the center. Conclusions: The new system offers the potential to acquire whole brain (Formula presented.) P MRSI with superior signal relative to the standard options.