The present invention relates to novel inhibitors of pVHL-Elongin C binding, methods for identifying such inhibitors as well as compounds comprising a first moiety binding to an Elongin B, Elongin C, Cul2 and/or Rbx1 complex, a linker and a second moiety for HIF-2α.
Novel inhibitors of pvhl-elongin c binding
Stefano Iacobelli;Nicola Tinari;Imma FICHERA;Enza PICCOLO
2014-01-01
Abstract
The present invention relates to novel inhibitors of pVHL-Elongin C binding, methods for identifying such inhibitors as well as compounds comprising a first moiety binding to an Elongin B, Elongin C, Cul2 and/or Rbx1 complex, a linker and a second moiety for HIF-2α.File in questo prodotto:
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