The present invention consists of a method for non-invasive monitoring of the presence of tumor disease in a patient, characterized by measuring the levels of the circulating Trop-2 protein in unfractionated serum obtained from the tumor patient. This method also allows non-invasive monitoring of tumor progression or regression, by comparing the levels of the Trop-2 biomarker measured in unfractionated serum samples taken at different times from the same patient. This method also allows the non-invasive monitoring of tumor response to therapy, wherein the levels of the Trop-2 biomarker are measured in unfractionated serum samples taken from the same patient before, during and after cancer therapy. It is part of the present invention a method for measuring the circulating Trop-2 protein in unfractionated serum.

Use of circulating serum trop-2 as new tumor biomarker

Marco Trerotola;Emanuela Guerra;
2017

Abstract

The present invention consists of a method for non-invasive monitoring of the presence of tumor disease in a patient, characterized by measuring the levels of the circulating Trop-2 protein in unfractionated serum obtained from the tumor patient. This method also allows non-invasive monitoring of tumor progression or regression, by comparing the levels of the Trop-2 biomarker measured in unfractionated serum samples taken at different times from the same patient. This method also allows the non-invasive monitoring of tumor response to therapy, wherein the levels of the Trop-2 biomarker are measured in unfractionated serum samples taken from the same patient before, during and after cancer therapy. It is part of the present invention a method for measuring the circulating Trop-2 protein in unfractionated serum.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11564/708008
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