The present invention refers to humanized anti-Trop-2 antibodies and their fragments, derivatives and conjugates that are able to recognise and bind with high affinity disctinct regions of the Trop-2 molecule. The present invention also teaches the use of such antibodies and of pharmaceutical compositions thereof for diagnosis and therapy of human pathologies, in particular cancer.

Humanized anti-Trop-2 monoclonal antibodies and uses thereof (Canadian Patent)

guerra emanuela
Primo
;
2015-01-01

Abstract

The present invention refers to humanized anti-Trop-2 antibodies and their fragments, derivatives and conjugates that are able to recognise and bind with high affinity disctinct regions of the Trop-2 molecule. The present invention also teaches the use of such antibodies and of pharmaceutical compositions thereof for diagnosis and therapy of human pathologies, in particular cancer.
2015
2968330
9-set-2025
9-set-2025
Mediterranea Theranostic Srl
ELETTRONICO
Inglese
Internazionale
Trop-2, humanized monoclonal antibodies, ADCC, anticancer therapy, preclinical efficacy
Goal 3: Good health and well-being
Goal 5: Gender equality
Brevetto concesso - Canada
no
6 Brevetti::6.1 Brevetto
none
Guerra, Emanuela; Alberti, Saverio
info:eu-repo/semantics/patent
285
2
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11564/898202
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