GARUFI, ALESSIA
GARUFI, ALESSIA
DIPARTIMENTO DI SCIENZE MEDICHE, ORALI E BIOTECNOLOGICHE
A ruthenium(II)-curcumin compound modulates NRF2 expression balancing the cancer cell death/survival outcome according to p53 status
2020-01-01 Garufi, A.; Baldari, S.; Pettinari, R.; Gilardini Montani, M. S.; D'Orazi, V.; Pistritto, G.; Crispini, A.; Giorno, E.; Toietta, G.; Marchetti, F.; Cirone, M.; D'Orazi, G.
Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategies
2016-01-01 Pistritto, G; Trisciuoglio, D; Ceci, C; Garufi, Alessia; D'Orazi, Gabriella
Autophagy manipulation as a strategy for efficient anticancer therapies: Possible consequences
2019-01-01 Cirone, M.; Gilardini Montani, M. S.; Granato, M.; Garufi, A.; Faggioni, A.; D'Orazi, G.
Clearing mutant p53 with natural compounds: implication for anticancer therapeutical approaches
2016-01-01 D'Orazi, G; Garufi, A; Cirone, M
HIPK2 as a Novel Regulator of Fibrosis
2023-01-01 Garufi, Alessia; Pistritto, Giuseppa; D'Orazi, Gabriella
HIPK2 in Angiogenesis: A Promising Biomarker in Cancer Progression and in Angiogenic Diseases
2023-01-01 Garufi, Alessia; D'Orazi, Valerio; Pistritto, Giuseppa; Cirone, Mara; D'Orazi, Gabriella
HIPK2 in Colon Cancer: A Potential Biomarker for Tumor Progression and Response to Therapies
2024-01-01 Verdina, Alessandra; Garufi, Alessia; D'Orazi, Valerio; D'Orazi, Gabriella
HIPK2 role in the tumor-host interaction: Impact on fibroblasts transdifferentiation CAF-like
2019-01-01 Garufi, Alessia; Traversi, Gianandrea; Cirone, Mara; D'Orazi, Gabriella
Hyperglycemia triggers HIPK2 protein degradation
2017-01-01 Baldari, Silvia; Garufi, Alessia; Granato, Marisa; Cuomo, Laura; Pistritto, Giuseppa; Cirone, Mara; D'Orazi, Gabriella
Interplay between endoplasmic reticulum (ER) stress and autophagy induces mutant p53H273 degradation
2020-01-01 Garufi, A.; Federici, G.; Gilardini Montani, M. S.; Crispini, A.; Cirone, M.; D'Orazi, G.
New Copper-Based Metallodrugs with Anti-Invasive Capacity
2023-01-01 Garufi, Alessia; Scarpelli, Francesca; Ricciardi, Loredana; Aiello, Iolinda; D’Orazi, Gabriella; Crispini, Alessandra
NRF2 activation in BON‑1 neuroendocrine cancer cells reduces the cytotoxic effects of a novel Ruthenium(II)‑curcumin compound: A pilot study
2024-01-01 Garufi, Alessia; Pettinari, Riccardo; Monteonofrio, Laura; Puliani, Giulia; Virdia, Ilaria; Appetecchia, Marialuisa; Marchetti, Fabio; Cirone, Mara; Soddu, Silvia; D'Orazi, Gabriella
NRF2 and Bip Interconnection Mediates Resistance to the Organometallic Ruthenium-Cymene Bisdemethoxycurcumin Complex Cytotoxicity in Colon Cancer Cells
2023-01-01 Garufi, Alessia; Pettinari, Riccardo; Marchetti, Fabio; Cirone, Mara; D'Orazi, Gabriella
Nuclear factor erythroid 2 (NF-E2) p45-related factor 2 interferes with homeodomain-interacting protein kinase 2/p53 activity to impair solid tumors chemosensitivity
2020-01-01 D'Orazi, G.; Garufi, A.; Cirone, M.
Oxidant species are involved in T/B-mediated ERK1/2 phosphorylation that activates p53-p21 axis to promote KSHV lytic cycle in PEL cells
2017-01-01 Gonnella, Roberta; Yadav, Shivangi; Gilardini Montani, Maria Saveria; Granato, Marisa; Santarelli, Roberta; Garufi, Alessia; D'Orazi, Gabriella; Faggioni, Alberto; Cirone, Mara
P53-Dependent PUMA to DRAM antagonistic interplay as a key molecular switch in cell-fate decision in normal/high glucose conditions
2017-01-01 Garufi, Alessia; Pistritto, Giuseppa; Baldari, Silvia; Toietta, Gabriele; Cirone, Mara; D'Orazi, Gabriella
P62/SQSTM1/Keap1/NRF2 Axis Reduces Cancer Cells Death-Sensitivity in Response to Zn(II)-Curcumin Complex
2021-01-01 Garufi, Alessia; Giorno, Eugenia; Gilardini Montani, Maria Saveria; Pistritto, Giuseppa; Crispini, Alessandra; Cirone, Mara; D'Orazi, Gabriella
PBA preferentially impairs cell survival of glioblastomas carrying mutp53 by reducing its expression level, stabilizing wtp53, downregulating the mevalonate kinase and dysregulating UPR
2020-01-01 Romeo, M. A.; Gilardini Montani, M. S.; Benedetti, R.; Garufi, A.; D'Orazi, G.; Cirone, M.
Reactivation of mutant p53 by capsaicin, the major constituent of peppers
2016-01-01 Garufi, Alessia; Pistritto, G; Cirone, M; D'Orazi, Gabriella
Recent Advances on Mutant p53: Unveiling Novel Oncogenic Roles, Degradation Pathways, and Therapeutic Interventions
2024-01-01 Cordani, Marco; Garufi, Alessia; Benedetti, Rossella; Tafani, Marco; Aventaggiato, Michele; D'Orazi, Gabriella; Cirone, Mara
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A ruthenium(II)-curcumin compound modulates NRF2 expression balancing the cancer cell death/survival outcome according to p53 status | 2020 | Garufi, A.; Baldari, S.; Pettinari, R.; Gilardini Montani, M. S.; D'Orazi, V.; Pistritto, G.; Crispini, A.; Giorno, E.; Toietta, G.; Marchetti, F.; Cirone, M.; D'Orazi, G. | |
| Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategies | 2016 | Pistritto, G; Trisciuoglio, D; Ceci, C; Garufi, Alessia; D'Orazi, Gabriella | |
| Autophagy manipulation as a strategy for efficient anticancer therapies: Possible consequences | 2019 | Cirone, M.; Gilardini Montani, M. S.; Granato, M.; Garufi, A.; Faggioni, A.; D'Orazi, G. | |
| Clearing mutant p53 with natural compounds: implication for anticancer therapeutical approaches | 2016 | D'Orazi, G; Garufi, A; Cirone, M | |
| HIPK2 as a Novel Regulator of Fibrosis | 2023 | Garufi, Alessia; Pistritto, Giuseppa; D'Orazi, Gabriella | |
| HIPK2 in Angiogenesis: A Promising Biomarker in Cancer Progression and in Angiogenic Diseases | 2023 | Garufi, Alessia; D'Orazi, Valerio; Pistritto, Giuseppa; Cirone, Mara; D'Orazi, Gabriella | |
| HIPK2 in Colon Cancer: A Potential Biomarker for Tumor Progression and Response to Therapies | 2024 | Verdina, Alessandra; Garufi, Alessia; D'Orazi, Valerio; D'Orazi, Gabriella | |
| HIPK2 role in the tumor-host interaction: Impact on fibroblasts transdifferentiation CAF-like | 2019 | Garufi, Alessia; Traversi, Gianandrea; Cirone, Mara; D'Orazi, Gabriella | |
| Hyperglycemia triggers HIPK2 protein degradation | 2017 | Baldari, Silvia; Garufi, Alessia; Granato, Marisa; Cuomo, Laura; Pistritto, Giuseppa; Cirone, Mara; D'Orazi, Gabriella | |
| Interplay between endoplasmic reticulum (ER) stress and autophagy induces mutant p53H273 degradation | 2020 | Garufi, A.; Federici, G.; Gilardini Montani, M. S.; Crispini, A.; Cirone, M.; D'Orazi, G. | |
| New Copper-Based Metallodrugs with Anti-Invasive Capacity | 2023 | Garufi, Alessia; Scarpelli, Francesca; Ricciardi, Loredana; Aiello, Iolinda; D’Orazi, Gabriella; Crispini, Alessandra | |
| NRF2 activation in BON‑1 neuroendocrine cancer cells reduces the cytotoxic effects of a novel Ruthenium(II)‑curcumin compound: A pilot study | 2024 | Garufi, Alessia; Pettinari, Riccardo; Monteonofrio, Laura; Puliani, Giulia; Virdia, Ilaria; Appetecchia, Marialuisa; Marchetti, Fabio; Cirone, Mara; Soddu, Silvia; D'Orazi, Gabriella | |
| NRF2 and Bip Interconnection Mediates Resistance to the Organometallic Ruthenium-Cymene Bisdemethoxycurcumin Complex Cytotoxicity in Colon Cancer Cells | 2023 | Garufi, Alessia; Pettinari, Riccardo; Marchetti, Fabio; Cirone, Mara; D'Orazi, Gabriella | |
| Nuclear factor erythroid 2 (NF-E2) p45-related factor 2 interferes with homeodomain-interacting protein kinase 2/p53 activity to impair solid tumors chemosensitivity | 2020 | D'Orazi, G.; Garufi, A.; Cirone, M. | |
| Oxidant species are involved in T/B-mediated ERK1/2 phosphorylation that activates p53-p21 axis to promote KSHV lytic cycle in PEL cells | 2017 | Gonnella, Roberta; Yadav, Shivangi; Gilardini Montani, Maria Saveria; Granato, Marisa; Santarelli, Roberta; Garufi, Alessia; D'Orazi, Gabriella; Faggioni, Alberto; Cirone, Mara | |
| P53-Dependent PUMA to DRAM antagonistic interplay as a key molecular switch in cell-fate decision in normal/high glucose conditions | 2017 | Garufi, Alessia; Pistritto, Giuseppa; Baldari, Silvia; Toietta, Gabriele; Cirone, Mara; D'Orazi, Gabriella | |
| P62/SQSTM1/Keap1/NRF2 Axis Reduces Cancer Cells Death-Sensitivity in Response to Zn(II)-Curcumin Complex | 2021 | Garufi, Alessia; Giorno, Eugenia; Gilardini Montani, Maria Saveria; Pistritto, Giuseppa; Crispini, Alessandra; Cirone, Mara; D'Orazi, Gabriella | |
| PBA preferentially impairs cell survival of glioblastomas carrying mutp53 by reducing its expression level, stabilizing wtp53, downregulating the mevalonate kinase and dysregulating UPR | 2020 | Romeo, M. A.; Gilardini Montani, M. S.; Benedetti, R.; Garufi, A.; D'Orazi, G.; Cirone, M. | |
| Reactivation of mutant p53 by capsaicin, the major constituent of peppers | 2016 | Garufi, Alessia; Pistritto, G; Cirone, M; D'Orazi, Gabriella | |
| Recent Advances on Mutant p53: Unveiling Novel Oncogenic Roles, Degradation Pathways, and Therapeutic Interventions | 2024 | Cordani, Marco; Garufi, Alessia; Benedetti, Rossella; Tafani, Marco; Aventaggiato, Michele; D'Orazi, Gabriella; Cirone, Mara |