| Nome |
# |
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EV20/NMS-P945, a Novel Thienoindole Based Antibody-Drug Conjugate Targeting HER-3 for Solid Tumors, file e4233f18-9584-2860-e053-6605fe0a460a
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87
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Oxidative Distress Induces Wnt/β-Catenin Pathway Modulation in Colorectal Cancer Cells: Perspectives on APC Retained Functions, file e4233f18-b2a2-2860-e053-6605fe0a460a
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78
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Antagonist of growth hormone-releasing hormone MIA-690 attenuates the progression and inhibits growth of colorectal cancer in mice, file e4233f18-e1fa-2860-e053-6605fe0a460a
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46
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Secreted Gal-3BP is a novel promising target for non-internalizing Antibody–Drug Conjugates, file e4233f17-0528-2860-e053-6605fe0a460a
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34
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Pyruvate prevents the development of age-dependent cognitive deficits in a mouse model of Alzheimer's disease without reducing amyloid and tau pathology, file e4233f18-fddb-2860-e053-6605fe0a460a
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34
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Inhibition of tumor growth and angiogenesis by SP-2, an anti-lectin, galactoside-binding soluble 3 binding protein (LGALS3BP) antibody., file e4233f16-3733-2860-e053-6605fe0a460a
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29
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PLC-gamma-1 phosphorylation status is prognostic of metastatic risk in patients with early-stage Luminal-A and -B breast cancer subtypes, file e4233f17-4b33-2860-e053-6605fe0a460a
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26
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The transcriptional terminator XRN2 and the RNA-binding protein Sam68 link alternative polyadenylation to cell cycle progression in prostate cancer, file ab6529be-8399-4dc7-9b12-85d3e32a2e28
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24
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High methylation levels of PCDH10 predict poor prognosis in patients with pancreatic ductal adenocarcinoma, file e4233f17-2562-2860-e053-6605fe0a460a
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23
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miR-205-5p-mediated downregulation of ErbB/HER receptors in breast cancer stem cells results in targeted therapy resistance, file e4233f15-4484-2860-e053-6605fe0a460a
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22
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Thymic Epithelial Tumors as a Model of Networking: Development of a Synergistic Strategy for Clinical and Translational Research Purposes, file e4233f17-ea92-2860-e053-6605fe0a460a
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21
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Anomalous Fusion of Right Pulmonary Artery to Aortic Arch: Case Report of a Rare and Fatal Congenital Malformation in a Newborn and a Literature Review, file e4233f17-0fc0-2860-e053-6605fe0a460a
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20
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Trop-2 induces ADAM10-mediated cleavage of E-cadherin and drives EMT-less metastasis in colon cancer, file e4233f18-bc55-2860-e053-6605fe0a460a
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18
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Prognostic relevance of LGALS3BP in human colorectal carcinoma, file e4233f17-ee8a-2860-e053-6605fe0a460a
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15
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Exosomes as pleiotropic players in pancreatic cancer, file e4233f18-87d9-2860-e053-6605fe0a460a
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15
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USP19 modulates cancer cell migration and invasion and acts as a novel prognostic marker in patients with early breast cancer, file e4233f18-ca41-2860-e053-6605fe0a460a
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15
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Trop-2 is a determinant of breast cancer survival., file e4233f17-859b-2860-e053-6605fe0a460a
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13
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Targeting vesicular lgals3bp by an antibody-drug conjugate as novel therapeutic strategy for neuroblastoma, file e4233f18-51bf-2860-e053-6605fe0a460a
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13
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Human cytomegalovirus infection enhances 5‑lipoxygenase and cycloxygenase‑2 expression in colorectal cancer, file 8e05e460-d3dc-420e-b46b-3f0383ca097c
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12
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Extracellular LGALS3BP: a potential disease marker and actionable target for antibody-drug conjugate therapy in glioblastoma, file b5a2d813-9694-474b-b6b6-8c6087c42654
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12
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A bicistronic CYCLIN D1-TROP2 mRNA chimera demonstrates a novel oncogenic mechanism in human cancer, file e4233f17-d712-2860-e053-6605fe0a460a
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12
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Overexpression of PY1289-HER3 in sporadic pulmonary carcinoid from patients bearing MEN1 gene variants, file e4233f17-ee87-2860-e053-6605fe0a460a
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12
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Combined effect of anti-BAG3 and anti-PD-1 treatment on macrophage infiltrate, CD8(+) T cell number and tumour growth in pancreatic cancer, file e4233f18-8d61-2860-e053-6605fe0a460a
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12
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Trop-2 cleavage by ADAM10 is an activator switch for cancer growth and metastasis, file e4233f18-ce6e-2860-e053-6605fe0a460a
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12
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Preclinical validation of 3-phosphoinositide-dependent protein kinase 1 inhibition in pancreatic cancer, file e4233f17-e4be-2860-e053-6605fe0a460a
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11
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Alterations of MEN1 and E-cadherin/β-catenin complex in sporadic pulmonary carcinoids, file e4233f15-007d-2860-e053-6605fe0a460a
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10
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Functional and prognostic significance of the genomic amplification of frizzled 6 (FZD6) in breast cancer, file e4233f16-dfd1-2860-e053-6605fe0a460a
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10
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Class II phosphoinositide 3-kinase C2β regulates a novel signaling pathway involved in breast cancer progression, file e4233f17-eebf-2860-e053-6605fe0a460a
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10
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p53, cathepsin D, Bcl-2 are joint prognostic indicators of breast cancer metastatic spreading, file e4233f18-2ec5-2860-e053-6605fe0a460a
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10
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The HSP90/R2TP assembly chaperone promotes cell proliferation in the intestinal epithelium, file e4233f18-cb27-2860-e053-6605fe0a460a
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10
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null, file e0d894a3-d993-4ea9-a20f-cdce6c8cf4bb
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9
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Vav1 Down-Modulates Akt2 Expression in Cells from Pancreatic Ductal Adenocarcinoma: Nuclear Vav1 as a Potential Regulator of Akt Related Malignancy in Pancreatic Cancer, file e4233f17-edd4-2860-e053-6605fe0a460a
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9
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Protective effects of growth hormone-releasing hormone analogs in DSS-induced colitis in mice, file e4233f18-9b95-2860-e053-6605fe0a460a
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8
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Wingless/It/β-catenin signaling in liver metastasis from colorectal cancer: A focus on biological mechanisms and therapeutic opportunities, file 41f40a18-6cec-4d9b-8c82-86c1bb1a944d
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6
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The 2EF Antibody Targets a Unique N-Terminal Epitope of Trop-2 and Enhances the In Vivo Activity of the Cancer-Selective 2G10 Antibody, file 47a7496c-5e19-4e93-9b87-ada3db679b24
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6
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Anti-LGALS3BP antibody-drug conjugate treatment induces durable and potent antitumor response in a preclinical model of adenoid cystic carcinoma, file 964f00b4-a892-436e-b396-946d6d41f49f
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6
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Pyruvate prevents the development of age-dependent cognitive deficits in a mouse model of Alzheimer's disease without reducing amyloid and tau pathology, file e4233f15-44a5-2860-e053-6605fe0a460a
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6
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HER-3 surface expression increases in advanced colorectal cancer representing a potential therapeutic target, file b81e5c5f-a118-4da4-a6b3-237f50c2d07c
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5
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Molecular expression profiling shows pseudohypoxia phenotype, vasculogenesis and mitochondrial dysfunction in head and neck paragangliomas, file e4233f17-5734-2860-e053-6605fe0a460a
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5
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GPR55 signalling promotes proliferation of pancreatic cancer cells and tumour growth in mice, and its inhibition increases effects of gemcitabine, file e4233f17-f5fe-2860-e053-6605fe0a460a
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5
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Vav1 down-modulates Akt in different breast cancer subtypes: a new promising chance to improve breast cancer outcome, file e4233f18-c63a-2860-e053-6605fe0a460a
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5
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Membranous Nectin-4 expression is a risk factor for distant relapse of T1-T2, N0 luminal-A early breast cancer, file 2b4ff7e3-523a-48cc-81af-781e794797b9
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4
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Loss of primary cilia promotes inflammation and carcinogenesis, file 7472e05b-3622-44c2-b7ea-fb1e6c193b92
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4
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LGALS3BP is a potential target of antibody-drug conjugates in oral squamous cell carcinoma, file a289b249-cb14-4c5e-b641-511a38584754
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4
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The mitotic checkpoint kinase BUB1 is a direct and actionable target of MYB in adenoid cystic carcinoma, file b12bc0f5-7828-40b3-b454-a8fa64358725
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4
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An immunohistochemically positive E-cadherin status is not always predictive for a good prognosis in human breast cancer., file e4233f18-4a50-2860-e053-6605fe0a460a
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4
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Lysosomal lipid switch sensitises to nutrient deprivation and mTOR targeting in pancreatic cancer, file 77a5d360-257e-4d44-b501-20f7c733e6de
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3
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Trop-1 Are Conserved Growth Stimulatory Molecules That Mark Early Stages of Tumor Progression, file e4233f14-eb86-2860-e053-6605fe0a460a
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3
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3D-informed targeting of the Trop-2 signal-activation site drives selective cancer vulnerability, file b86f2386-edf1-48f0-bea2-d31e64505ff8
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2
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Phylogenetic conservation of Trop-2 across species—rodent and primate genomics model anti-Trop-2 therapy for pre-clinical benchmarks, file bd10f8fa-7c56-45d4-abbd-18dbd334f4a0
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2
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An immunohistochemically positive E-cadherin status is not always predictive for a good prognosis in human breast cancer., file e4233f14-f8e5-2860-e053-6605fe0a460a
|
2
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Trop-2 induces tumor growth through Akt and determines sensitivity to Akt inhibitors, file e4233f17-d865-2860-e053-6605fe0a460a
|
2
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ABCC3 is a novel target for the treatment of pancreatic cancer, file e4233f17-eac9-2860-e053-6605fe0a460a
|
2
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Cyclin A2 maintains colon homeostasis and is a prognostic factor in CRC, file e4233f18-1a68-2860-e053-6605fe0a460a
|
2
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Trop-2, Na+/K+ ATPase, CD9, PKCα, cofilin assemble a membrane signaling super-complex that drives colorectal cancer growth and invasion, file e4233f18-e990-2860-e053-6605fe0a460a
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2
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Soft tissue integration of different abutment surfaces: An experimental study with histological analysis, file 50e57c9c-b2ff-4501-8e95-b204d2e8a53d
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1
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Changes of topoisomerase IIalpha expression in breast tumors after neoadjuvant chemotherapy predicts relapse-free survival, file e4233f14-edac-2860-e053-6605fe0a460a
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1
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Phospholipase Cgamma1 is required for metastasis development and progression, file e4233f14-f102-2860-e053-6605fe0a460a
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1
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P53 mutations in colorectal cancer from northern Iran: Relationships with site of tumor origin, microsatellite instability and K-ras mutations, file e4233f14-f1a4-2860-e053-6605fe0a460a
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1
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Exenatide promotes cognitive enhancement and positive brain metabolic changes in PS1-KI mice but has no effects in 3xTg-AD animals, file e4233f15-0566-2860-e053-6605fe0a460a
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1
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| Totale |
781 |