| Nome |
# |
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Choline Chloride-Based DES as Solvents/Catalysts/Chemical Donors in Pharmaceutical Synthesis, file e4233f18-8ca8-2860-e053-6605fe0a460a
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118
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HDAC Inhibitors for the Therapy of Triple Negative Breast Cancer, file 6da8c85a-7489-4c52-8d9d-a10f318a0a66
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103
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Anticancer Activity of Stilbene-Based Derivatives, file e4233f19-2033-2860-e053-6605fe0a460a
|
75
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Design, synthesis and biological evaluation of aromatase inhibitors based on sulfonates and sulfonamides of resveratrol, file e4233f18-7e82-2860-e053-6605fe0a460a
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43
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null, file e4233f18-a76a-2860-e053-6605fe0a460a
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38
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Resveratrol Derivative Exhibits Marked Antiproliferative Actions, Affecting Stemness in Pancreatic Cancer Cells, file 11bca291-d33c-4c66-a5a5-720ae37927bb
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33
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Sulfonimide and Amide Derivatives as Novel PPARα Antagonists: Synthesis, Antiproliferative Activity, and Docking Studies, file e4233f17-d995-2860-e053-6605fe0a460a
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33
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Antiglioma Activity of Aryl and Amido-Aryl Acetamidine Derivatives Targeting iNOS: Synthesis and Biological Evaluation, file e4233f17-b301-2860-e053-6605fe0a460a
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31
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Novel Phenyldiazenyl Fibrate Analogues as PPAR α/γ/δ Pan-Agonists for the Amelioration of Metabolic Syndrome, file e4233f18-b852-2860-e053-6605fe0a460a
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31
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Searching for New Tools to Counteract the Helicobacter pylori Resistance: The Positive Action of Resveratrol Derivatives, file e4233f18-492f-2860-e053-6605fe0a460a
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30
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Synthesis and biological characterization of 3-(imidazol-1-ylmethyl)piperidine sulfonamides as aromatase inhibitors, file e4233f19-4794-2860-e053-6605fe0a460a
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29
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Anti-Inflammatory, Antioxidant, and WAT/BAT-Conversion Stimulation Induced by Novel PPAR Ligands: Results from Ex Vivo and In Vitro Studies, file 4073d51e-af0a-47d7-9c54-966bee986d14
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28
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Benzothiazole Derivatives Endowed with Antiproliferative Activity in Paraganglioma and Pancreatic Cancer Cells: Structure-Activity Relationship Studies and Target Prediction Analysis, file 478db8d9-4fef-42b4-bcca-3e36eb51aef6
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28
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Development of a Rapid Mass Spectrometric Determination of AMP and Cyclic AMP for PDE3 Activity Study: Application and Computational Analysis for Evaluating the Effect of a Novel 2-oxo-1,2-dihydropyridine-3-carbonitrile Derivative as PDE-3 Inhibitor, file e4233f17-ad61-2860-e053-6605fe0a460a
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28
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The Benzimidazole-Based Anthelmintic Parbendazole: A Repurposed Drug Candidate That Synergizes with Gemcitabine in Pancreatic Cancer, file e4233f17-5d24-2860-e053-6605fe0a460a
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22
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Different binding and recognition modes of GL479, a dual agonist of Peroxisome Proliferator-Activated Receptor α/γ, file e4233f19-55eb-2860-e053-6605fe0a460a
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22
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Targeting neuronal nitric oxide synthase as a valuable strategy for the therapy of neurological disorders, file e4233f15-ffb7-2860-e053-6605fe0a460a
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21
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Fibrate-based N-acylsulphonamides targeting carbonic anhydrases: synthesis, biochemical evaluation, and docking studies, file e4233f18-7444-2860-e053-6605fe0a460a
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21
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Effects of dichloroacetate as single agent or in combination with GW6471 and metformin in paraganglioma cells, file e4233f16-ec1f-2860-e053-6605fe0a460a
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19
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PPAR Ligands Induce Antiviral Effects Targeting Perturbed Lipid Metabolism during SARS-CoV-2, HCV, and HCMV Infection, file e4233f18-9792-2860-e053-6605fe0a460a
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19
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Selective Acetamidine-Based Nitric Oxide Synthase Inhibitors: Synthesis, Docking, and Biological Studies, file e4233f17-f40c-2860-e053-6605fe0a460a
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16
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Acetamidine-Based iNOS Inhibitors as Molecular Tools to Counteract Inflammation in BV2 Microglial Cells, file e4233f17-9991-2860-e053-6605fe0a460a
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15
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The Positive Regulation of eNOS Signaling by PPAR Agonists in Cardiovascular Diseases, file e4233f19-6710-2860-e053-6605fe0a460a
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15
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Phenylsulfonimide PPARα Antagonists Enhance Nrf2 Activation and Promote Oxidative Stress-Induced Apoptosis/Pyroptosis in MCF7 Breast Cancer Cells, file 62990d7b-7ac7-4e57-bfc3-b658f14ada32
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13
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Inhibition of PPARγ by Natural Compounds as a Promising Strategy in Obesity and Diabetes, file e4233f17-759c-2860-e053-6605fe0a460a
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13
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Synthesis and Biological Evaluation of Halogenated E-Stilbenols as Promising Antiaging Agents, file e4233f18-1ae2-2860-e053-6605fe0a460a
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12
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New azolyl-derivatives as multitargeting agents against breast cancer and fungal infections: synthesis, biological evaluation and docking study, file e4233f18-7ec0-2860-e053-6605fe0a460a
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12
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Screening of NOS activity and selectivity of newly synthesized acetamidines using RP-HPLC, file e4233f19-2472-2860-e053-6605fe0a460a
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12
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Activators of Nrf2 to Counteract Neurodegenerative Diseases, file 496d1492-2a10-4f71-8e28-43ca207532ac
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10
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Emerging Effects of Resveratrol Derivatives in Cells Involved in Oral Wound Healing: A Preliminary Study, file c393a36e-b42c-44f0-a506-bfe0cfb1f52f
|
10
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Structural development studies of PPARs ligands based on tyrosine scaffold, file e4233f16-fdf5-2860-e053-6605fe0a460a
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10
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Discovery of N-{3-[(ethanimidoylamino)methyl]benzyl}-L-prolinamide dihydrochloride:
A new potent and selective inhibitor of the inducible nitric oxide synthase as a
promising agent for the therapy of malignant glioma, file e4233f19-5add-2860-e053-6605fe0a460a
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10
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The Inhibition of the Inducible Nitric Oxide Synthase Enhances the DPSC Mineralization under LPS-Induced Inflammation, file df753bae-01c3-459c-a0d4-d0ed5143576d
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9
|
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Discovery of N-{3-[(ethanimidoylamino)methyl]benzyl}-L-prolinamide dihydrochloride:
A new potent and selective inhibitor of the inducible nitric oxide synthase as a
promising agent for the therapy of malignant glioma, file e4233f16-d09a-2860-e053-6605fe0a460a
|
8
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|
Olea europea L. Leaves and Hibiscus sabdariffa L. Petals Extracts: Herbal Mix from Cardiovascular Network Target to Gut Motility Dysfunction Application, file e4233f18-fdcc-2860-e053-6605fe0a460a
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8
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Preface to Nitric Oxide Modulators in Health and Disease I, file 84459c15-c1fd-4302-aeb5-230aa24f6676
|
7
|
|
Structural development studies of PPARs ligands based on tyrosine scaffold, file e4233f19-569d-2860-e053-6605fe0a460a
|
7
|
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Selective Acetamidine-Based Nitric Oxide Synthase Inhibitors: Synthesis, Docking, and Biological Studies, file e4233f19-53c7-2860-e053-6605fe0a460a
|
6
|
|
Novel Phenyldiazenyl Fibrate Analogues as PPAR α/γ/δ Pan-Agonists for the Amelioration of Metabolic Syndrome, file e4233f17-83ad-2860-e053-6605fe0a460a
|
5
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Selective Inhibitors of the Inducible Nitric Oxide Synthase as Modulators of Cell Responses in LPS-Stimulated Human Monocytes, file e4233f18-c9f7-2860-e053-6605fe0a460a
|
5
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|
null, file e4233f18-ec35-2860-e053-6605fe0a460a
|
5
|
|
Synthesis and biological characterization of 3-(imidazol-1-ylmethyl)piperidine sulfonamides as aromatase inhibitors, file e4233f19-1769-2860-e053-6605fe0a460a
|
5
|
|
Neuronal Nitric Oxide Synthase and Post-Translational Modifications in the Development of Central Nervous System Diseases: Implications and Regulation, file 861cf7b6-d7bc-480d-a7d0-ca96abd0fc6c
|
4
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Synthesis and Biological Evaluation of 2-Heteroarylthioalkanoic Acid Analogues of Clofibric Acid as Peroxisome Proliferator-Activated Receptor alfa Agonists, file e4233f14-f1d9-2860-e053-6605fe0a460a
|
4
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In vitro protective effects of resveratrol and stilbene alkanoic derivatives on induced oxidative stress on c2c12 and mcf7 cells, file e4233f16-61d7-2860-e053-6605fe0a460a
|
4
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|
Design, synthesis and biological evaluation of imidazole and triazole-based carbamates as novel aromatase inhibitors, file e4233f18-31bc-2860-e053-6605fe0a460a
|
4
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Synthesis and biological evaluation of gemfibrozil chiral analogs as potential PPARa agonists, file e4233f17-a7f8-2860-e053-6605fe0a460a
|
3
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|
Synthesis, structure-activity relationships and molecular docking studies of phenyldiazenyl sulfonamides as aromatase inhibitors, file e4233f18-8530-2860-e053-6605fe0a460a
|
3
|
|
null, file e4233f18-edc5-2860-e053-6605fe0a460a
|
3
|
|
Resveratrol-based compounds and neurodegeneration: Recent insight in multitarget therapy, file e4233f18-f3d9-2860-e053-6605fe0a460a
|
3
|
|
Anticancer Activity of Stilbene-Based Derivatives, file e4233f19-3cdd-2860-e053-6605fe0a460a
|
3
|
|
Different binding and recognition modes of GL479, a dual agonist of Peroxisome Proliferator-Activated Receptor α/γ, file e4233f19-5e54-2860-e053-6605fe0a460a
|
3
|
|
New amidine-benzenesulfonamides as iNOS inhibitors for the therapy of the triple negative breast cancer, file ad725347-bdd1-40ea-8c04-238d25cb3b67
|
2
|
|
Synthesis, biological evaluation and docking studies of N-substituted acetamidines as selective inhibitors of inducible nitric oxide synthase, file e4233f14-f1da-2860-e053-6605fe0a460a
|
2
|
|
Multitarget PPARγ agonists as innovative modulators of the metabolic syndrome, file e4233f17-7884-2860-e053-6605fe0a460a
|
2
|
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N-acylsulfonamides: synthetic routes and biological potential in medicinal chemistry, file e4233f17-7aa8-2860-e053-6605fe0a460a
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2
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Cytotoxic effect of a family of Peroxisome Proliferator-Activated Receptor antagonists in colorectal and pancreatic cancer cell lines, file e4233f17-8054-2860-e053-6605fe0a460a
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2
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Development of Fibrates as Important Scaffolds in Medicinal Chemistry, file e4233f17-820f-2860-e053-6605fe0a460a
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2
|
|
Synthesis and structure-activity relationships of fibrate-based analogues inside PPARs, file e4233f17-a743-2860-e053-6605fe0a460a
|
2
|
|
Screening of NOS activity and selectivity of newly synthesized acetamidines using RP-HPLC, file e4233f19-0fd2-2860-e053-6605fe0a460a
|
2
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|
The excitation-contraction coupling on C2C12 skeletal muscle myotubes was modulated by NO-donor ester of gemfibrozil, file 7696c417-92ce-4cf0-a226-3204a5bdfa3f
|
1
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Synthesis of 2-aryloxypropanoic acids analogues of clofibric acid and assignment of the absolute configuration by 1H NMR spectroscopy and DFT calculations, file e4233f14-f19c-2860-e053-6605fe0a460a
|
1
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N-Substituted acetamidines and 2-methylimidazole derivatives as selective inhibitors of neuronal nitric oxide synthase, file e4233f14-fad0-2860-e053-6605fe0a460a
|
1
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Seeking for Non-Zinc-Binding MMP-2 Inhibitors: Synthesis, Biological Evaluation and Molecular Modelling Studies, file e4233f15-9811-2860-e053-6605fe0a460a
|
1
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|
PPARα agonists based on stilbene and its bioisosteres: Biological evaluation and docking studies, file e4233f15-aece-2860-e053-6605fe0a460a
|
1
|
|
Synthesis of naphthyl-, quinolin- and anthracenyl analogues of clofibric acid as PPARα agonists, file e4233f15-b906-2860-e053-6605fe0a460a
|
1
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PPARα as Potential Therapeutic Target for Neurodegenerative Diseases, file e4233f17-1150-2860-e053-6605fe0a460a
|
1
|
|
The Selective Acetamidine-Based iNOS Inhibitor CM544 Reduces Glioma Cell Proliferation by Enhancing PARP-1 Cleavage In Vitro, file e4233f17-1c68-2860-e053-6605fe0a460a
|
1
|
|
Synthesis, characterization and evaluation of gemfibrozil-stilbene hybrid as antioxidant agent, file e4233f17-7472-2860-e053-6605fe0a460a
|
1
|
|
Fibrate-derived N-(methylsulfonyl)amides with antagonistic properties on PPARa, file e4233f17-80ad-2860-e053-6605fe0a460a
|
1
|
|
Time factor in antiretroviral adherence: analysis of adherence to single-tablet regimens versus multiple-tablet regimens over a 5-year period, file e4233f18-524e-2860-e053-6605fe0a460a
|
1
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|
A Novel Prodrug of a nNOS Inhibitor with Improved Pharmacokinetic Potential, file e4233f18-8383-2860-e053-6605fe0a460a
|
1
|
|
Recent developments of amidine-like compounds as selective NOS inhibitors, file e4233f18-c049-2860-e053-6605fe0a460a
|
1
|
|
Synthesis, biological evaluation, and docking study of indole aryl sulfonamides as aromatase inhibitors, file e4233f19-1257-2860-e053-6605fe0a460a
|
1
|
| Totale |
1.049 |