MELFI, FRANCESCO
MELFI, FRANCESCO
DIPARTIMENTO DI FARMACIA
A Multitarget Approach against Neuroinflammation: Alkyl Substituted Coumarins as Inhibitors of Enzymes Involved in Neurodegeneration
2023-01-01 Berrino, Emanuela; Carradori, Simone; Carta, Fabrizio; Melfi, Francesco; Gallorini, Marialucia; Poli, Giulio; Tuccinardi, Tiziano; Fernández-Bolaños, José G; López, Óscar; Petzer, Jacobus P; Petzer, Anél; Guglielmi, Paolo; Secci, Daniela; Supuran, Claudiu T
Azo derivatives of monoterpenes as anti-Helicobacter pylori agents: from synthesis to structure-based target investigation
2024-01-01 Melfi, F.; Fantacuzzi, M.; Carradori, S.; D'Agostino, I.; Ammazzalorso, A.; Mencarelli, N.; Gallorini, M.; Spano, M.; Guglielmi, P.; Agamennone, M.; Ali, S. H.; Al-Samydai, A.; Sisto, F.
C-Myc Expression in Oral Squamous Cell Carcinoma: Molecular Mechanisms in Cell Survival and Cancer Progression
2022-01-01 Marconi, G. D.; Della Rocca, Y.; Fonticoli, L.; Melfi, F.; Rajan, T. S.; Carradori, S.; Pizzicannella, J.; Trubiani, O.; Diomede, F.
Coumarin– and Dipicolylamine–Terpenoid Hybrids as Selective Carbonic Anhydrases IX and XII Inhibitors: Mechanistic Insights and Selective Anti-Cancer Potential
2026-01-01 Saravanan, Venkatesan; Angeli, Andrea; Melfi, Francesco; Amodio, Nicola; Valentino, Ilenia; Gentile, Massimo; D'Agostino, Ilaria; Muthukumaradoss, Kathiravan; Zengin, Gokhan; Moi, Davide; Simsek, Rahime; Supuran, Claudiu T.; Carradori, Simone
Drug design of tyrosinase inhibitors
2024-01-01 Melfi, F.; Carradori, S.; Granese, A.; Osmanovic, A.; Campestre, C.
Emerging compounds and therapeutic strategies to treat infections from Trypanosoma brucei: an overhaul of the last 5-years patents
2023-01-01 Melfi, F.; Carradori, S.; Campestre, C.; Haloci, E.; Ammazzalorso, A.; Grande, R.; D'Agostino, I.
Evaluation of Anti-inflammatory Activity of Microwave Extracts of Thymus Algeriensis: In Vitro, in Vivo and in Silico Studies
2025-01-01 Boutaoui, N.; Acila, M.; Lariche, N.; Lamoui, R.; Khelafi, A.; Campestre, C.; Melfi, F.; Locatelli, M.
Fine-tuning of membrane permeability by reversible photoisomerization of aryl-azo derivatives of thymol embedded in lipid nanoparticles
2024-01-01 Moffa, S.; Carradori, S.; Melfi, F.; Fontana, A.; Ciulla, M.; Di Profio, P.; Aschi, M.; Wolicki, R. D.; Pilato, S.; Siani, G.
Hybridization Approach Applied to Umbelliferon and Vanilloids toward New Inhibitors of Carbonic Anhydrases IX and XII with In Vitro Antiproliferative and Anti-inflammatory Activities
2026-01-01 Melfi, Francesco; Mencarelli, Noemi; Carradori, Simone; Gallorini, Marialucia; Angeli, Andrea; Poli, Giulio; Cataldi, Amelia; D'Agostino, Ilaria; Di Credico, Andrea; Di Baldassarre, Angela; Tuccinardi, Tiziano; Supuran, Claudiu T.
Inhibition of Pseudomonas aeruginosa Carbonic Anhydrases, Exploring Ciprofloxacin Functionalization Toward New Antibacterial Agents: An In-Depth Multidisciplinary Study
2024-01-01 Marinacci, B.; D'Agostino, I.; Angeli, A.; Carradori, S.; Melfi, F.; Grande, R.; Corsiani, M.; Ferraroni, M.; Agamennone, M.; Tondo, A. R.; Zara, S.; Puca, V.; Pellegrini, B.; Vagaggini, C.; Dreassi, E.; Patrauchan, M. A.; Capasso, C.; Nicolotti, O.; Carta, F.; Supuran, C. T.
Natural products as a source of new anticancer chemotypes
2023-01-01 Melfi, F.; Carradori, S.; Mencarelli, N.; Campestre, C.; Gallorini, M.; Di Giacomo, S.; Di Sotto, A.
Nature as a source and inspiration for human monoamine oxidase B (hMAO-B) inhibition: A review of the recent advances in chemical modification of natural compounds
2023-01-01 Melfi, F.; Carradori, S.; Angeli, A.; D'Agostino, I.
Nature-Inspired Compounds: Synthesis and Antibacterial Susceptibility Testing of Eugenol Derivatives against H. pylori Strains
2023-01-01 Carradori, S.; Ammazzalorso, A.; Niccolai, S.; Tanini, D.; D'Agostino, I.; Melfi, F.; Capperucci, A.; Grande, R.; Sisto, F.
O-derivatization of natural tropolone and β-thujaplicin leading to effective inhibitors of human carbonic anhydrases IX and XII
2025-01-01 Melfi, F.; D'Agostino, I.; Carradori, S.; Carta, F.; Angeli, A.; Costa, G.; Renzi, G.; Cikos, A.; Vullo, D.; Resetar, J.; Ferraroni, M.; Baroni, C.; Mancuso, F.; Gitto, R.; Ambrosio, F. A.; Marchese, E.; Torcasio, R.; Amodio, N.; Capasso, C.; Alcaro, S.; Supuran, C. T.
Phenolic terpenes in liposomal bilayers: Unraveling physicochemical interactions and membrane perturbation via biophysical and computational approaches
2025-01-01 Pilato, S.; Carradori, S.; Melfi, F.; Di Giacomo, S.; Ciavarella, S.; Ciulla, M.; Fontana, A.; Di Profio, P.; Aschi, M.; Moffa, S.; Siani, G.
Potential of MAO-B Inhibitors with Multi-target Inhibition and Antioxidant Properties for the Treatment of Neurodegenerative Disorders
2026-01-01 Shaldam, Moataz A.; Carradori, Simone; Melfi, Francesco; Guglielmi, Paolo; Diomede, Francesca; Piattelli, Maurizio; Tawfik, Haytham O.
Rational design, synthesis, and biological evaluation of novel selective inhibitors of human and bacterial carbonic anhydrase isoforms with broad therapeutic potential
2026-05-13 Melfi, Francesco
Recent developments of agents targeting Vibrio cholerae: patents and literature data
2024-01-01 Melfi, F.; Carradori, S.; Mencarelli, N.; Campestre, C.; Granese, A.; Mori, M.
Tyrosinase enzyme and its inhibitors: An update of the literature
2023-01-01 Carradori, S.; Melfi, F.; Resetar, J.; Simsek, R.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A Multitarget Approach against Neuroinflammation: Alkyl Substituted Coumarins as Inhibitors of Enzymes Involved in Neurodegeneration | 2023 | Berrino, Emanuela; Carradori, Simone; Carta, Fabrizio; Melfi, Francesco; Gallorini, Marialucia; Poli, Giulio; Tuccinardi, Tiziano; Fernández-Bolaños, José G; López, Óscar; Petzer, Jacobus P; Petzer, Anél; Guglielmi, Paolo; Secci, Daniela; Supuran, Claudiu T | |
| Azo derivatives of monoterpenes as anti-Helicobacter pylori agents: from synthesis to structure-based target investigation | 2024 | Melfi, F.; Fantacuzzi, M.; Carradori, S.; D'Agostino, I.; Ammazzalorso, A.; Mencarelli, N.; Gallorini, M.; Spano, M.; Guglielmi, P.; Agamennone, M.; Ali, S. H.; Al-Samydai, A.; Sisto, F. | |
| C-Myc Expression in Oral Squamous Cell Carcinoma: Molecular Mechanisms in Cell Survival and Cancer Progression | 2022 | Marconi, G. D.; Della Rocca, Y.; Fonticoli, L.; Melfi, F.; Rajan, T. S.; Carradori, S.; Pizzicannella, J.; Trubiani, O.; Diomede, F. | |
| Coumarin– and Dipicolylamine–Terpenoid Hybrids as Selective Carbonic Anhydrases IX and XII Inhibitors: Mechanistic Insights and Selective Anti-Cancer Potential | 2026 | Saravanan, Venkatesan; Angeli, Andrea; Melfi, Francesco; Amodio, Nicola; Valentino, Ilenia; Gentile, Massimo; D'Agostino, Ilaria; Muthukumaradoss, Kathiravan; Zengin, Gokhan; Moi, Davide; Simsek, Rahime; Supuran, Claudiu T.; Carradori, Simone | |
| Drug design of tyrosinase inhibitors | 2024 | Melfi, F.; Carradori, S.; Granese, A.; Osmanovic, A.; Campestre, C. | |
| Emerging compounds and therapeutic strategies to treat infections from Trypanosoma brucei: an overhaul of the last 5-years patents | 2023 | Melfi, F.; Carradori, S.; Campestre, C.; Haloci, E.; Ammazzalorso, A.; Grande, R.; D'Agostino, I. | |
| Evaluation of Anti-inflammatory Activity of Microwave Extracts of Thymus Algeriensis: In Vitro, in Vivo and in Silico Studies | 2025 | Boutaoui, N.; Acila, M.; Lariche, N.; Lamoui, R.; Khelafi, A.; Campestre, C.; Melfi, F.; Locatelli, M. | |
| Fine-tuning of membrane permeability by reversible photoisomerization of aryl-azo derivatives of thymol embedded in lipid nanoparticles | 2024 | Moffa, S.; Carradori, S.; Melfi, F.; Fontana, A.; Ciulla, M.; Di Profio, P.; Aschi, M.; Wolicki, R. D.; Pilato, S.; Siani, G. | |
| Hybridization Approach Applied to Umbelliferon and Vanilloids toward New Inhibitors of Carbonic Anhydrases IX and XII with In Vitro Antiproliferative and Anti-inflammatory Activities | 2026 | Melfi, Francesco; Mencarelli, Noemi; Carradori, Simone; Gallorini, Marialucia; Angeli, Andrea; Poli, Giulio; Cataldi, Amelia; D'Agostino, Ilaria; Di Credico, Andrea; Di Baldassarre, Angela; Tuccinardi, Tiziano; Supuran, Claudiu T. | |
| Inhibition of Pseudomonas aeruginosa Carbonic Anhydrases, Exploring Ciprofloxacin Functionalization Toward New Antibacterial Agents: An In-Depth Multidisciplinary Study | 2024 | Marinacci, B.; D'Agostino, I.; Angeli, A.; Carradori, S.; Melfi, F.; Grande, R.; Corsiani, M.; Ferraroni, M.; Agamennone, M.; Tondo, A. R.; Zara, S.; Puca, V.; Pellegrini, B.; Vagaggini, C.; Dreassi, E.; Patrauchan, M. A.; Capasso, C.; Nicolotti, O.; Carta, F.; Supuran, C. T. | |
| Natural products as a source of new anticancer chemotypes | 2023 | Melfi, F.; Carradori, S.; Mencarelli, N.; Campestre, C.; Gallorini, M.; Di Giacomo, S.; Di Sotto, A. | |
| Nature as a source and inspiration for human monoamine oxidase B (hMAO-B) inhibition: A review of the recent advances in chemical modification of natural compounds | 2023 | Melfi, F.; Carradori, S.; Angeli, A.; D'Agostino, I. | |
| Nature-Inspired Compounds: Synthesis and Antibacterial Susceptibility Testing of Eugenol Derivatives against H. pylori Strains | 2023 | Carradori, S.; Ammazzalorso, A.; Niccolai, S.; Tanini, D.; D'Agostino, I.; Melfi, F.; Capperucci, A.; Grande, R.; Sisto, F. | |
| O-derivatization of natural tropolone and β-thujaplicin leading to effective inhibitors of human carbonic anhydrases IX and XII | 2025 | Melfi, F.; D'Agostino, I.; Carradori, S.; Carta, F.; Angeli, A.; Costa, G.; Renzi, G.; Cikos, A.; Vullo, D.; Resetar, J.; Ferraroni, M.; Baroni, C.; Mancuso, F.; Gitto, R.; Ambrosio, F. A.; Marchese, E.; Torcasio, R.; Amodio, N.; Capasso, C.; Alcaro, S.; Supuran, C. T. | |
| Phenolic terpenes in liposomal bilayers: Unraveling physicochemical interactions and membrane perturbation via biophysical and computational approaches | 2025 | Pilato, S.; Carradori, S.; Melfi, F.; Di Giacomo, S.; Ciavarella, S.; Ciulla, M.; Fontana, A.; Di Profio, P.; Aschi, M.; Moffa, S.; Siani, G. | |
| Potential of MAO-B Inhibitors with Multi-target Inhibition and Antioxidant Properties for the Treatment of Neurodegenerative Disorders | 2026 | Shaldam, Moataz A.; Carradori, Simone; Melfi, Francesco; Guglielmi, Paolo; Diomede, Francesca; Piattelli, Maurizio; Tawfik, Haytham O. | |
| Rational design, synthesis, and biological evaluation of novel selective inhibitors of human and bacterial carbonic anhydrase isoforms with broad therapeutic potential | 2026 | Melfi, Francesco | |
| Recent developments of agents targeting Vibrio cholerae: patents and literature data | 2024 | Melfi, F.; Carradori, S.; Mencarelli, N.; Campestre, C.; Granese, A.; Mori, M. | |
| Tyrosinase enzyme and its inhibitors: An update of the literature | 2023 | Carradori, S.; Melfi, F.; Resetar, J.; Simsek, R. |