A simplified model is suggested to describe the aggregation and fusion processes of liposomes. This model is based on three points: a) evaluation of number of clusters and aggregation and fusion sites as a function of time; b) probabilistic analysis of size distribution of clusters and fusion products; c) prediction of the experimental signal chosen to monitor the overall fusion. First attempts to compare this model with the experimental data, obtained with the RET assay, show a satisfactory agreement.
A simplified model for liposome aggregation and fusion
DI MARZIO, Luisa;
1993-01-01
Abstract
A simplified model is suggested to describe the aggregation and fusion processes of liposomes. This model is based on three points: a) evaluation of number of clusters and aggregation and fusion sites as a function of time; b) probabilistic analysis of size distribution of clusters and fusion products; c) prediction of the experimental signal chosen to monitor the overall fusion. First attempts to compare this model with the experimental data, obtained with the RET assay, show a satisfactory agreement.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
