The thiophene-, benzothiazole- and pyridine-thioaryloxyacids analogues of clofibric acid were synthesized and their antiplatelet activity was screened. Some compounds exhibited antiaggregating properties. The platelet-related haemostasis was measured on a PFA-100® analyzer using bull blood.

Synthesis and antiplatelet activity of thioaryloxyacids analogues of clofibric acid

AMMAZZALORSO, Alessandra;AMOROSO, Rosa;BETTONI, Giancarlo;DE FILIPPIS, Barbara;GIAMPIETRO, Letizia;TRICCA, Maria Luisa;
2005

Abstract

The thiophene-, benzothiazole- and pyridine-thioaryloxyacids analogues of clofibric acid were synthesized and their antiplatelet activity was screened. Some compounds exhibited antiaggregating properties. The platelet-related haemostasis was measured on a PFA-100® analyzer using bull blood.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11564/118668
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