The thiophene-, benzothiazole- and pyridine-thioaryloxyacids analogues of clofibric acid were synthesized and their antiplatelet activity was screened. Some compounds exhibited antiaggregating properties. The platelet-related haemostasis was measured on a PFA-100® analyzer using bull blood.
Synthesis and antiplatelet activity of thioaryloxyacids analogues of clofibric acid
AMMAZZALORSO, Alessandra;AMOROSO, Rosa;BETTONI, Giancarlo;DE FILIPPIS, Barbara;GIAMPIETRO, Letizia;TRICCA, Maria Luisa;
2005-01-01
Abstract
The thiophene-, benzothiazole- and pyridine-thioaryloxyacids analogues of clofibric acid were synthesized and their antiplatelet activity was screened. Some compounds exhibited antiaggregating properties. The platelet-related haemostasis was measured on a PFA-100® analyzer using bull blood.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
