Cytokine is a term used for a large group of proteins that are produced by a variety of cells in the body and act to stimulate, or inhibit, the functions of the same cells that produce them or of other cell types. The IL-17 family members are different in expressions and proinflammatory responses. IL- 17B mRNA is expressed at very high levels in the spinal cord and at lower and variable levels in the trachea, prostate, lung, small intestine, testes, adrenal, and pancreas.IL-17 may induce COX-2 gene expression in several cells. In fact, recently it has been found that IL-17 can exert direct transcritional an posttranscriptional control over target proinflammatory cytokines
Interleukin-17: a revisited study.
CONTI, Pio;BARBACANE, Renato Carmine;GRILLI, Alfredo;DE LUTIIS, Maria Anna;RICCIONI, Graziano;SABATINO, Giuseppe
2004-01-01
Abstract
Cytokine is a term used for a large group of proteins that are produced by a variety of cells in the body and act to stimulate, or inhibit, the functions of the same cells that produce them or of other cell types. The IL-17 family members are different in expressions and proinflammatory responses. IL- 17B mRNA is expressed at very high levels in the spinal cord and at lower and variable levels in the trachea, prostate, lung, small intestine, testes, adrenal, and pancreas.IL-17 may induce COX-2 gene expression in several cells. In fact, recently it has been found that IL-17 can exert direct transcritional an posttranscriptional control over target proinflammatory cytokinesI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
