Due to the increased incidence of Helicobacter pylori strains resistant to the antibiotics commonly used for H. pylori eradication, the search for alternative therapies based on the use of new compounds with antibacterial and/or preventive activity against H. pylori infection is of increasing interest.1 Boropinic acid is a prenyloxycinnamic acid isolated from the Australian shrub Boronia pinnata Sm. (Fam. Rutaceae) that was recently reported to inhibit in vitro the growth of H. pylori strain DSMZ 4867 (MIC = 6.17 µM).
Boropinic Acid, a Novel Inhibitor of Helicobacter pylori Stomach Colonization
MENGHINI, LUIGI;GENOVESE, Salvatore;EPIFANO, Francesco
2009-01-01
Abstract
Due to the increased incidence of Helicobacter pylori strains resistant to the antibiotics commonly used for H. pylori eradication, the search for alternative therapies based on the use of new compounds with antibacterial and/or preventive activity against H. pylori infection is of increasing interest.1 Boropinic acid is a prenyloxycinnamic acid isolated from the Australian shrub Boronia pinnata Sm. (Fam. Rutaceae) that was recently reported to inhibit in vitro the growth of H. pylori strain DSMZ 4867 (MIC = 6.17 µM).File in questo prodotto:
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