BACKGROUND: The aim of this study was to evaluate clinically, histologically, and ultrastructurally the integration process of the acellular dermal matrix used to increase the band of keratinized tissue while achieving gingival inflammation control. METHODS: Ten patients exhibiting a mucogingival problem with bands of keratinized tissue <or=1 mm and gingival inflammation of the related teeth were included in the study. The surgical procedures were performed to augment the gingival tissue using acellular dermal matrix. Clinical measurements were assessed at baseline and after 3 months. A specimen of the allograft and surrounding tissues was obtained immediately before the surgery and 4 minutes and 1, 2, 3, 4, 6, and 10 weeks after grafting. RESULTS: Clinically, a gain of keratinized tissue of 2.92 +/- 0.65 mm was observed after 3 months. Histologically and ultrastructurally, many macrophages were observed phagocytosing preexisting collagen fibers in the first weeks. From week 2 on, fibroblasts synthesizing new collagen, epithelial cells colonizing the graft surface, and revascularization were noticed. After 6 weeks it was difficult to find the acellular dermal matrix preexisting collagen fibers. This process of substitution was completed after 10 weeks, when the reepithelialization of the entire graft throughout a well-structured basement membrane was achieved.

Acellular dermal matrix graft for gingival augmentation: a preliminary clinical, histologic, and ultrastructural evaluation.

SCARANO, Antonio;IEZZI, GIOVANNA;PIATTELLI, Adriano;
2009-01-01

Abstract

BACKGROUND: The aim of this study was to evaluate clinically, histologically, and ultrastructurally the integration process of the acellular dermal matrix used to increase the band of keratinized tissue while achieving gingival inflammation control. METHODS: Ten patients exhibiting a mucogingival problem with bands of keratinized tissue
File in questo prodotto:
File Dimensione Formato  
26 ACELLULAR DERMAL MATRIX J PERIO.pdf

Solo gestori archivio

Tipologia: Documento in Post-print
Dimensione 653.57 kB
Formato Adobe PDF
653.57 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11564/137859
Citazioni
  • ???jsp.display-item.citation.pmc??? 16
  • Scopus 50
  • ???jsp.display-item.citation.isi??? 44
social impact