Villoglandular adenocarcinoma of uterine cervix: a case report

We report a case of villoglandular adenocarcinoma of the uterine cervix, discovered in a 69-year-old woman. The patient underwent a radical Wertheim hysterectomy and bilateral pelvic lymphoadenectomy and is alive and well, with no evidence of recurrent disease after 5 years from diagnosis. 13 reports totaling 70 patients with diagnoses of villoglandular adenocarcinoma have been published. The patients ages ranged from 22 to 61 years. Well-differentiated villoglandular adenocarcinoma of the uterine cervix has been recently recognized and described as a distinctive histologic entity which develops in young women. It is possible that cases of villoglandular adenocarcinoma in older women, as our case, were previously considered to represent different histologic types of adenocarcinoma. The differential diagnosis of villoglandular adenocarcinoma is important for prognostic and treatment reasons.