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Effect of diabetes on early and late survival after isolated first coronary bypass surgery in multivessel disease.

DI GIAMMARCO, GABRIELE;
2003-01-01
2003
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
WOS:000180579300027
125
144
154
11
12538998
Diabetes has not yet been investigated as a risk factor for early and late cardiac-related death.Patients operated on from January 1988 to December 1999 were considered; 767 were diabetic (group D) and 2593 were nondiabetic (group ND). Patients with preoperative hemodynamic deterioration were excluded. Early (30-day) mortality (any causes and cardiac causes) was evaluated with univariate analysis and stepwise logistic regression. Ten-year actuarial freedom from death of any cause and cardiac death was also assessed with univariate and Cox analyses.Early mortality was 2.2\% (group D, 3.3\%; group ND, 1.9\%; P =.023). Early cardiac mortality was 1.3\% (group D, 2.2\%; group ND, 1.1\%; P =.0016). Diabetes was an independent risk factor only for cardiac death and not for death of any cause. Five-year survival was 93.5\% +/- 0.5\% (group D, 92.5\% +/- 1.1\%; group ND, 93.9\% +/- 0.6\%; P =.0304). Diabetes was not an independent risk factor. Five-year freedom for cardiac death was 96.3\% +/- 0.4\% (group D, 94.9\% +/- 0.9\%; group ND, 96.6\% +/- 0.4\%; P =.0155). Diabetes was an independent risk factor. However, if only the patients who survived the first 30 days are considered, diabetes disappears as a risk factor (5-year freedom for cardiac death, 97.8\% +/- 0.3\%; group D, 97.3\% +/- 0.8\%; group ND, 97.9\% +/- 0.4\%; P = 0.2389).Diabetes is an independent risk factor for early cardiac death only. Long-term survival in patients who survive the first 30 days is not statistically significantly different for diabetic and nondiabetic patients. In fact, the rates appear very similar.
Actuarial Analysis; Case-Control Studies; Coronary Artery Bypass; Coronary Disease; Diabetes Mellitus; Female; Humans; Logistic Models; Male; Middle Aged; Proportional Hazards Models; Risk Factors; Survival Analysis; Time Factors
http://dx.doi.org/10.1067/mtc.2003.73
2-s2.0-0037252021
8
info:eu-repo/semantics/article
262
A. M., Calafiore; M. D., Mauro; DI GIAMMARCO, Gabriele; M., Contini; G., Vitolla; A. L., Iacò; C., Canosa; S., D'Alessandro
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11564/177074
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