We present a new SQUID based susceptometer for liver iron concentration (LIC) assessment. The instrument is operated with an inhomogeneous AC magnetizing field. The susceptometer is based on 7 channels, each consisting of a sensing unit and of an additional unit for the compensation of the applied field residual and its variation. Each unit is a second order gradiometer and is coupled to a de SQUID with a parallel washer configuration. The compensation module output is digitally processed and coupled to the sensing gradiometer by means of an additional feedback path. The estimation of LIC is based on a numerical model of the subject's torso obtained from the segmentation of ultrasound images.
An AC magnetizing field biosusceptometer using a SQUID based sensor with additional compensation module
DELLA PENNA, Stefania;DEL GRATTA, Cosimo;CIANFLONE, FRANCESCO;PIZZELLA, Vittorio;ROMANI, Gian Luca
2003-01-01
Abstract
We present a new SQUID based susceptometer for liver iron concentration (LIC) assessment. The instrument is operated with an inhomogeneous AC magnetizing field. The susceptometer is based on 7 channels, each consisting of a sensing unit and of an additional unit for the compensation of the applied field residual and its variation. Each unit is a second order gradiometer and is coupled to a de SQUID with a parallel washer configuration. The compensation module output is digitally processed and coupled to the sensing gradiometer by means of an additional feedback path. The estimation of LIC is based on a numerical model of the subject's torso obtained from the segmentation of ultrasound images.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
