Many bone substitutes have been proposed for bone regeneration, and researchers have focused on the interactions occurring between grafts and host tissue, as the biologic response of host tissue is related to the origin of the biomaterial. Bone substitutes used in oral and maxillofacial surgery could be categorized according to their biologic origin and source as autologous bone graft when obtained from the same individual receiving the graft; homologous bone graft, or allograft, when harvested from an individual other than the one receiving the graft; animal-derived heterologous bone graft, or xenograft, when derived from a species other than human; and alloplastic graft, made of bone substitute of synthetic origin. The aim of this review is to describe the most commonly used bone substitutes, according to their origin, and to focus on the biologic events that ultimately lead to the integration of a biomaterial with the host tissue. © 2016 Elsevier Inc.

Biologic and clinical aspects of integration of different bone substitutes in oral surgery: a literature review

Zizzari, Vincenzo Luca
;
ZARA, SUSI;CATALDI, Amelia
2016-01-01

Abstract

Many bone substitutes have been proposed for bone regeneration, and researchers have focused on the interactions occurring between grafts and host tissue, as the biologic response of host tissue is related to the origin of the biomaterial. Bone substitutes used in oral and maxillofacial surgery could be categorized according to their biologic origin and source as autologous bone graft when obtained from the same individual receiving the graft; homologous bone graft, or allograft, when harvested from an individual other than the one receiving the graft; animal-derived heterologous bone graft, or xenograft, when derived from a species other than human; and alloplastic graft, made of bone substitute of synthetic origin. The aim of this review is to describe the most commonly used bone substitutes, according to their origin, and to focus on the biologic events that ultimately lead to the integration of a biomaterial with the host tissue. © 2016 Elsevier Inc.
File in questo prodotto:
File Dimensione Formato  
1-s2.0-S2212440316300463-main.pdf

Solo gestori archivio

Descrizione: Article
Tipologia: PDF editoriale
Dimensione 250.66 kB
Formato Adobe PDF
250.66 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Accepted version.pdf

accesso aperto

Tipologia: Documento in Post-print
Dimensione 365.29 kB
Formato Adobe PDF
365.29 kB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11564/654377
Citazioni
  • ???jsp.display-item.citation.pmc??? 29
  • Scopus 63
  • ???jsp.display-item.citation.isi??? 56
social impact