Second Primary Lung Cancer: A Current Problem in Long-Survivor Cancer Patients

Background: Lung may be the site of synchronous or metachronous second primary malignancies (SPM) with an incidence between 0.8 and 14.5% of cases. Synchronous or metachronous SPM present, however, diagnostic and therapeutic challenges. The authors report their experience in the treatment of second primary lung tumors. Methods: A retrospective study from 2008 to 2014 was conducted in patients with synchronous or metachronous second primary lung cancer. Results: 30 patients (69.8%) underwent to pulmonary lobectomy, 4 (9,3%) to segmentectomy and 6 (14.0%) to wedge resections (Table n.1). Lung-sparing resections were referred to patients with unsuitable respiratory volumes for anatomical ones. The presence in the medical history of an intra- or extrathoracic primary cancer does not significantly influence survival, while the second primary malignancy’s stage is crucial. Conclusions: Lobectomy with hilar-mediastinal lymph node dissection should be offered to all suitable patient.