Editorial: Supramolecular Systems in Nanomedicines: Therapeutic Applications and Future Perspectives - Part I.

During the last few decades large strides have been made in nanomedicine and a first generation of nanotherapeutics have already made it to the market. The great potential of nanomedicine largely stems from its multidisciplinary nature, where the fields of medicine, chemistry, physics, biology, mathematics, and engineering are integrated. By combining the knowledge of all these fields innovative supramolecular nanotherapeutics can be designed for the treatment of a variety of diseases. Supramolecular nanosystems provide several advantages over conventional drugs, such as increasing the circulation time, improving drug accumulation in the target region and decreasing side effects. Recently, several supramolecular nanosystems combining organic and inorganic biomaterials were synthesized and nanotherapeutics showing multiple efficacy were developed to treat different pathologies. In this scenario, nanotherapeutics advanced as the new therapeutic perspective in nanomedicines. This proposal was focused on the impact of supramolecular systems in nanomedicine. In particular, a summary of therapeutic applications and future perspectives of different systems, formulated using inorganic and organic biomaterials, were presented. Experts in the field of supramolecular chemistry and nanomedicine were invited to contribute. The contributions were divided into two separate issues containing both research and review articles. A special cover for both issues was provided from two different authors, which contributed with research and/or review articles.