BACKGROUND: The aim of this comparative registry study was to evaluate the supplementation with Pycnogenol (R) in subjects with Behcet syndrome (BS) with symptoms impairing their quality of life despite being in a remitting phase of the disease. METHODS: Thirty-four patients with a confirmed diagnosis of BS were divided into the control group (without supplement) or the active group, in this specific case using Pycnogenol (R) (Horphag Research LTD) supplement at the daily dose of 150 mg (50 mg tid) for 4 weeks. RESULTS: All subjects receiving Pycnogenol (R) reported a significant decrease in symptoms, such as burning/pain due to dryness and ulcerations (P<0.05). In addition, Pycnogenol (R) showed important anti-inflammatory activity by decreasing ESR, leucocytosis and Pathergy Test response. CONCLUSIONS: Pycnogenol (R) may be a useful supplementation for the management of BS.
Behçet syndrome: effects of Pycnogenol® supplementation during regression phases.
Belcaro G
;Corsi M
;Cotellese R
;Feragalli B
;
2018-01-01
Abstract
BACKGROUND: The aim of this comparative registry study was to evaluate the supplementation with Pycnogenol (R) in subjects with Behcet syndrome (BS) with symptoms impairing their quality of life despite being in a remitting phase of the disease. METHODS: Thirty-four patients with a confirmed diagnosis of BS were divided into the control group (without supplement) or the active group, in this specific case using Pycnogenol (R) (Horphag Research LTD) supplement at the daily dose of 150 mg (50 mg tid) for 4 weeks. RESULTS: All subjects receiving Pycnogenol (R) reported a significant decrease in symptoms, such as burning/pain due to dryness and ulcerations (P<0.05). In addition, Pycnogenol (R) showed important anti-inflammatory activity by decreasing ESR, leucocytosis and Pathergy Test response. CONCLUSIONS: Pycnogenol (R) may be a useful supplementation for the management of BS.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
