Direct NMR screening of natural products obtained from hot water extracts of medicinal species is accomplished through STD and tr-NOESY experiments on a crude mixture and a given protein receptor. It is shown, with use of a mushroom extract as model case, that this protocol may provide a fast and simple method, particularly useful in natural products chemistry, through which to detect the presence of ligands for a target receptor. ((c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005).

Screening by NMR: A new approach for the study of bioactive natural products? The example of Pleurotus ostreatus hot water extract

Politi, Matteo;
2005-01-01

Abstract

Direct NMR screening of natural products obtained from hot water extracts of medicinal species is accomplished through STD and tr-NOESY experiments on a crude mixture and a given protein receptor. It is shown, with use of a mushroom extract as model case, that this protocol may provide a fast and simple method, particularly useful in natural products chemistry, through which to detect the presence of ligands for a target receptor. ((c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005).
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11564/704100
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