Fuchs' endothelial corneal dystrophy (FECD) is a progressive and potentially a sight threatening disease, and a common indication for corneal grafting in the elderly. Aberrant thickening of Descemet's membrane, formation of microscopic excrescences (guttae) and gradual loss of corneal endothelial cells are the hallmarks of the disease. The aim of this study was to identify differentially abundant proteins between FECD-affected and unaffected Descemet's membrane.
Reduced expression of Apolipoprotein E and Immunoglobulin heavy constant gamma 1 proteins in Fuchs' endothelial corneal dystrophy
Ronci, Maurizio;Urbani, Andrea;
2019
Abstract
Fuchs' endothelial corneal dystrophy (FECD) is a progressive and potentially a sight threatening disease, and a common indication for corneal grafting in the elderly. Aberrant thickening of Descemet's membrane, formation of microscopic excrescences (guttae) and gradual loss of corneal endothelial cells are the hallmarks of the disease. The aim of this study was to identify differentially abundant proteins between FECD-affected and unaffected Descemet's membrane.File in questo prodotto:
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2019-Kuot_et_al-Clinical_&_Experimental_Ophthalmology.pdf
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