Lentigo maligna (LM) and lentigo maligna melanoma (LMM) are renown to present a subclinical spread that often extends widelyin the surrounding photodamaged skin. Previous studies showed that subclinical spread of melanoma was associated to lesion size[1-3], ill-defined margins[4], head and neck or central face localization[3, 5, 6], patient age ≥ 60-65 years[2, 6], phototype III-IV[5], incompletely excised or recurrent tumors[1, 4], history of previous treatment[6], nests formation[4], dermal invasion[1], and ≥ 1 mitoses/mm2 [6]. To analyze more thoroughly this argument, we performed a prospective study evaluating clinical, dermoscopic and histological features associated with subclinical spread of LM and LMM of the face.

May melanophages hinder the subclinical spread of lentigo maligna and lentigo maligna melanoma? Results from a pilot study

Gualdi, G;
2021-01-01

Abstract

Lentigo maligna (LM) and lentigo maligna melanoma (LMM) are renown to present a subclinical spread that often extends widelyin the surrounding photodamaged skin. Previous studies showed that subclinical spread of melanoma was associated to lesion size[1-3], ill-defined margins[4], head and neck or central face localization[3, 5, 6], patient age ≥ 60-65 years[2, 6], phototype III-IV[5], incompletely excised or recurrent tumors[1, 4], history of previous treatment[6], nests formation[4], dermal invasion[1], and ≥ 1 mitoses/mm2 [6]. To analyze more thoroughly this argument, we performed a prospective study evaluating clinical, dermoscopic and histological features associated with subclinical spread of LM and LMM of the face.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11564/741563
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