Differential diagnosis between radiation necrosis and tumour recurrence is important in the clinical management of patients with glioma. We performed an overview of the literature in order to summarize the role of 11C-methionine positron emission tomography (MET-PET) in this setting. This functional imaging method appears to have a high sensitivity, specificity, and accuracy in differentiating between glioma recurrence and radiation necrosis. Nevertheless, possible false negative and false positive results of MET-PET should be well kept in mind in the management of patients with glioma.
Usefulness of 11C-Methionine Positron Emission Tomography in Differential Diagnosis between Recurrent Tumours and Radiation Necro-sis in Patients with Glioma: An Overview
Vittoria Mattoli, MariaPrimo
;Trevisi, Gianluca;
2012-01-01
Abstract
Differential diagnosis between radiation necrosis and tumour recurrence is important in the clinical management of patients with glioma. We performed an overview of the literature in order to summarize the role of 11C-methionine positron emission tomography (MET-PET) in this setting. This functional imaging method appears to have a high sensitivity, specificity, and accuracy in differentiating between glioma recurrence and radiation necrosis. Nevertheless, possible false negative and false positive results of MET-PET should be well kept in mind in the management of patients with glioma.File in questo prodotto:
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