The clinical, functional, and structural pattern of chronic lung disease of prematurity has changed enormously in last years, mirroring a better perinatal management and an increasing lung immaturity with the survival of increasingly premature infants. Respiratory symptoms and lung function impairment related to prematurity seem to improve over time, but premature birth increases the likelihood of lung function impairment in late childhood, predisposing to chronic obstructive pulmonary disease (COPD). It is mandatory to identify those individuals born premature who are at risk for developing long-term lung disease through a better awareness of physicians, the use of standardized CT imaging scores, and a more comprehensive periodic lung function evaluation. The aim of this narrative review was to provide a systematic approach to lifelong respiratory symptoms, lung function impairment, and lung structural anomalies in order to better understand the specific role of prematurity on lung health.

Lifelong Lung Sequelae of Prematurity

Dodi, Giulia;Ciarelli, Francesca;Chiarelli, Francesco;Attanasi, Marina
2022-01-01

Abstract

The clinical, functional, and structural pattern of chronic lung disease of prematurity has changed enormously in last years, mirroring a better perinatal management and an increasing lung immaturity with the survival of increasingly premature infants. Respiratory symptoms and lung function impairment related to prematurity seem to improve over time, but premature birth increases the likelihood of lung function impairment in late childhood, predisposing to chronic obstructive pulmonary disease (COPD). It is mandatory to identify those individuals born premature who are at risk for developing long-term lung disease through a better awareness of physicians, the use of standardized CT imaging scores, and a more comprehensive periodic lung function evaluation. The aim of this narrative review was to provide a systematic approach to lifelong respiratory symptoms, lung function impairment, and lung structural anomalies in order to better understand the specific role of prematurity on lung health.
2022
Inglese
ELETTRONICO
19
5273
16
DLCO; chronic obstructive disease; lung function; prematurity; Child; Disease Progression; Female; Humans; Infant; Infant, Low Birth Weight; Infant, Newborn; Lung; Pregnancy; Infant, Premature, Diseases; Lung Diseases; Premature Birth
https://www.mdpi.com/1660-4601/19/9/5273
no
6
263
Di Filippo, Paola; Dodi, Giulia; Ciarelli, Francesca; Di Pillo, Sabrina; Chiarelli, Francesco; Attanasi, Marina
info:eu-repo/semantics/article
1 Contributo su Rivista::1.2 Recensione in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11564/790438
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