Neurostimulation is a technique that allows to study the human brain using an external signal which modifies its current activity. The stimulation is usually performed with fixed parameters, in a classical open-loop control paradigm. This strategy does not consider the current status of the brain to adaptively modify the stimulation parameters such as location, intensity and timing. In control theory, the latter strategy is called closed-loop control and it is becoming popular in neuroscience community since it allows to study the causal relationship between brain and behaviour, and it paves the way to personalize treatments in clinics. Here, we reviewed this new branch of study, by introducing control theory and presenting the neurostimulation techniques that are implementing closed-loop neuromodulation.
Closing the loop between neurostimulation and control theory
Guidotti R.;Basti A.;Pieramico G.;D'Andrea A.;Romani G. L.;Pizzella V.;Marzetti L.
2023-01-01
Abstract
Neurostimulation is a technique that allows to study the human brain using an external signal which modifies its current activity. The stimulation is usually performed with fixed parameters, in a classical open-loop control paradigm. This strategy does not consider the current status of the brain to adaptively modify the stimulation parameters such as location, intensity and timing. In control theory, the latter strategy is called closed-loop control and it is becoming popular in neuroscience community since it allows to study the causal relationship between brain and behaviour, and it paves the way to personalize treatments in clinics. Here, we reviewed this new branch of study, by introducing control theory and presenting the neurostimulation techniques that are implementing closed-loop neuromodulation.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
