Based on histopathology and molecular genetics, ovarian epithelial cancer consists of mainly five separate diseases: a) high-grade serous (70 %); b) endometrioid (10 %); c) clear cell (10 %); d) mucinous (3-4 %); and e) low-grade serous (< 5 %) carcinomas. These tumors, which account for over 95 % of cases, represent 5 distinct diseases with different prognosis and treatments. This review summarizes recent advances in the molecular pathology which have greatly improved our understanding of the biology of ovarian carcinomas and are also relevant to patient management. Copyright © 2024 ARáN edICIoNeS, S. l.
Ovarian carcinomas: clinicopathological and molecular characteristics. Comments on the 2014 FIGO staging system
D´Angelo, Emanuela;
2024-01-01
Abstract
Based on histopathology and molecular genetics, ovarian epithelial cancer consists of mainly five separate diseases: a) high-grade serous (70 %); b) endometrioid (10 %); c) clear cell (10 %); d) mucinous (3-4 %); and e) low-grade serous (< 5 %) carcinomas. These tumors, which account for over 95 % of cases, represent 5 distinct diseases with different prognosis and treatments. This review summarizes recent advances in the molecular pathology which have greatly improved our understanding of the biology of ovarian carcinomas and are also relevant to patient management. Copyright © 2024 ARáN edICIoNeS, S. l.File in questo prodotto:
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Carcinomas de ovario_Clin-Pat y mol_Prat et al_15.01.2025 (1).pdf
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