Immune thrombocytopenia (ITP) is a rare hematologic disorder characterized by low platelet counts due to an immune-mediated destruction of platelets. While corticosteroids, intravenous immunoglobulin (IVIG) are the mainstays of treatment, a subset of patients may remain refractory to these therapies. Here, we present a case of a 6-year-old girl diagnosed with refractory ITP, who failed to respond to standard therapies but showed a remarkable clinical improvement with avatrombopag, a thrombopoietin receptor agonist. Copyright © 2025 Sau, Di Prinzio, Onofrillo, Russo, Santoro and Di Ianni.
Case Report: A case of pediatric persistent refractory ITP responsive to avatrombopag
Santoro, Nicole;Di Ianni, Mauro
2025-01-01
Abstract
Immune thrombocytopenia (ITP) is a rare hematologic disorder characterized by low platelet counts due to an immune-mediated destruction of platelets. While corticosteroids, intravenous immunoglobulin (IVIG) are the mainstays of treatment, a subset of patients may remain refractory to these therapies. Here, we present a case of a 6-year-old girl diagnosed with refractory ITP, who failed to respond to standard therapies but showed a remarkable clinical improvement with avatrombopag, a thrombopoietin receptor agonist. Copyright © 2025 Sau, Di Prinzio, Onofrillo, Russo, Santoro and Di Ianni.File in questo prodotto:
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