The effects of Cd, on PHA stimulated proliferation and cytokine release from human PBMC in presence of Se, Zn and Cu salts were the object of this study. 10-4 and 10-5 M Cd exerted an inhibitory action, while Cu was slightly immunotoxic and 10-4 and 10-5 M. Se and Zn exerted a stimulatory effect; 10-6 M salts did not exert significant immune effects. Moreover, 10-4 and 10-5 M Se or Zn counteracted the immunotoxic effects of 10-5 M Cd possibly with different metabolic mechanisms.
Modulation of selenium, zinc and copper on immunotoxic effects of cadmium|Modulazione di selenio, zinco e rame su effetti immunotossici del cadmio
Di Giampaolo L.;Di Gioacchino M.;Castellani M. L.;Boscolo P.
2004-01-01
Abstract
The effects of Cd, on PHA stimulated proliferation and cytokine release from human PBMC in presence of Se, Zn and Cu salts were the object of this study. 10-4 and 10-5 M Cd exerted an inhibitory action, while Cu was slightly immunotoxic and 10-4 and 10-5 M. Se and Zn exerted a stimulatory effect; 10-6 M salts did not exert significant immune effects. Moreover, 10-4 and 10-5 M Se or Zn counteracted the immunotoxic effects of 10-5 M Cd possibly with different metabolic mechanisms.File in questo prodotto:
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