Thermal stabilization is important for assuring a sample quality and prevent protein denaturation. Presepsin is a new reliable biomarker of sepsis produced in response to bacterial infections. However, before its inclusion into clinical practice several criteria need to be fulfilled. One of these regards the samples thermostability after a long-term refrigeration in different biological fluids (blood, urine, saliva) that can constitute a confounding factor for Presepsin reliability as diagnostic test. On this light, this review offers an update of studies analyzing presepsin after sample thawing.
Effects of temperature on presepsin assessment in biological fluids
Botondi, Valentina;D'Adamo, Ebe;Trubiani, Oriana;Gazzolo, Diego
2023-01-01
Abstract
Thermal stabilization is important for assuring a sample quality and prevent protein denaturation. Presepsin is a new reliable biomarker of sepsis produced in response to bacterial infections. However, before its inclusion into clinical practice several criteria need to be fulfilled. One of these regards the samples thermostability after a long-term refrigeration in different biological fluids (blood, urine, saliva) that can constitute a confounding factor for Presepsin reliability as diagnostic test. On this light, this review offers an update of studies analyzing presepsin after sample thawing.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
