Transcranial magnetic stimulation (TMS) is a non-invasive technique that modulates brain networks by inducing a localized electric field (E-field) through a single coil placed over the scalp. The location and orientation of this E-field are crucial parameters as they influence cortical activity and, consequently, brain network communication. Recently, the development of multi-locus TMS (mTMS) has provided a tool to precisely modify the E-field without manually repositioning the coil. This enables systematic investigation of the effects of stimulation on brain networks by dynamically adjusting stimulation parameters. In this study, we explored how the position of the E-field during mTMS stimulation influences electroencephalographic (EEG) functional connectivity. Our analysis aimed to demonstrate that variations of the stimulation site result in distinct modulations of functional connectivity between different stimulation sites.
Beyond the standard TMS: Functional connectivity modulation with multi-locus TMS
Pieramico, G.
Primo
;Guidotti, R.Secondo
;Voso, D.;Lucarelli, D.;Ilmoniemi, R. J.;Romani, G. L.;Pizzella, V.Penultimo
;Marzetti, L.Ultimo
2025-01-01
Abstract
Transcranial magnetic stimulation (TMS) is a non-invasive technique that modulates brain networks by inducing a localized electric field (E-field) through a single coil placed over the scalp. The location and orientation of this E-field are crucial parameters as they influence cortical activity and, consequently, brain network communication. Recently, the development of multi-locus TMS (mTMS) has provided a tool to precisely modify the E-field without manually repositioning the coil. This enables systematic investigation of the effects of stimulation on brain networks by dynamically adjusting stimulation parameters. In this study, we explored how the position of the E-field during mTMS stimulation influences electroencephalographic (EEG) functional connectivity. Our analysis aimed to demonstrate that variations of the stimulation site result in distinct modulations of functional connectivity between different stimulation sites.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
