Formulation and characterization of prednisolone compressed lozenges as a low-dose formulation

This poster was produced while attending the PhD programme in Medical Biotechnologies at the University of "G. d'Annunzio" Chieti - Pescara, Cycle XXXIX, with the support of a scholarship co-financed by the Ministerial Decree no. 117 of 2nd March 2023, based on the NRRP - funded by the European Union - NextGenerationEU - Mission 4 "Education and Research", Component 2 "From Research to Business", Investment 3.3, and by the company Aenova group Latina site. The poster was produced during the mobility period at Rīga Stradiņš University - Faculty of Pharmacy (Riga, Latvia), by the Lead Reasearch Group under the supervision of Dr. Valentyn Mohylyuk. The feasibility study in object aimed to provide prednisolone compressed lozenges as a paediatric low-dosage option. It also aimed to investigate how the ratio of lubricant and binder can influence quality critical attributes and biopharmaceutical behaviour on finished product. To this scope, DoE method was used to investigate the technological role of excipients and to better understand the best profile formulation.