Nome |
# |
Reconsidering anion inhibitors in the general context of drug design studies of modulators of activity of the classical enzyme carbonic anhydrase, file e4233f18-597b-2860-e053-6605fe0a460a
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490
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Carbonic anhydrase inhibitors targeting metabolism and tumor microenvironment, file e4233f18-08b1-2860-e053-6605fe0a460a
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152
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Innovative Extraction Techniques and Hyphenated Instrument Configuration for Complex Matrices Analysis, file e4233f17-2460-2860-e053-6605fe0a460a
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134
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Tagetes spp. Essential Oils and Other Extracts: Chemical Characterization and Biological Activity, file e4233f17-022c-2860-e053-6605fe0a460a
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120
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New Frontiers in Selective Human MAO-B Inhibitors, file e4233f19-2a38-2860-e053-6605fe0a460a
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116
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Effects of the Hydroethanolic Extract of Lycopodium selago L. on Scopolamine-Induced Memory Deficits in Zebrafish, file e4233f18-daef-2860-e053-6605fe0a460a
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99
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Development of novel techniques to extract phenolic compounds from Romanian cultivars of Prunus domestica L. and their biological properties, file e4233f18-e930-2860-e053-6605fe0a460a
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85
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Liquid phase and microwave-assisted extractions for multi-component phenolic pattern determination of five Romanian Galium species coupled with bioassays, file e4233f17-108d-2860-e053-6605fe0a460a
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78
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Therapeutic Uses and Pharmacological Properties of Shallot (Allium ascalonicum): A Systematic Review, file 0386fb9d-8d27-4929-843e-dbad6b45167d
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59
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Synthesis and evaluation of a large library of nitroxoline derivatives as pancreatic cancer antiproliferative agents, file e4233f17-b5de-2860-e053-6605fe0a460a
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55
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Development of thiazolidinones as fungal carbonic anhydrase inhibitors, file e4233f17-838b-2860-e053-6605fe0a460a
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52
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Selective Inhibition of Helicobacter pylori Carbonic Anhydrases by Carvacrol and Thymol Could Impair Biofilm Production and the Release of Outer Membrane Vesicles, file e4233f18-841b-2860-e053-6605fe0a460a
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48
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Fisetin as a Senotherapeutic Agent: Biopharmaceutical Properties and Crosstalk between Cell Senescence and Neuroprotection, file e4233f18-9dfd-2860-e053-6605fe0a460a
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47
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Design, synthesis and biological evaluation of aromatase inhibitors based on sulfonates and sulfonamides of resveratrol, file e4233f18-7e82-2860-e053-6605fe0a460a
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43
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C-Myc Expression in Oral Squamous Cell Carcinoma: Molecular Mechanisms in Cell Survival and Cancer Progression, file e9571a0a-d7da-4ce8-b6d2-3ade9474c805
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43
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Analysis of imidazoles and triazoles in biological samples after MicroExtraction by Packed Sorbent, file e4233f16-8448-2860-e053-6605fe0a460a
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42
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null, file e4233f18-a76a-2860-e053-6605fe0a460a
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38
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Benzo[b]tiophen-3-ol derivatives as effective inhibitors of human monoamine oxidase: design, synthesis, and biological activity, file e4233f17-e9dc-2860-e053-6605fe0a460a
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37
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Coumarin-Based Dual Inhibitors of Human Carbonic Anhydrases and Monoamine Oxidases Featuring Amino Acyl and (Pseudo)-Dipeptidyl Appendages: In Vitro and Computational Studies, file d736a0ef-6ac8-457e-b99d-f94d70aade00
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36
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Identification and characterization of the α-CA in the outer membrane vesicles produced by Helicobacter pylori, file e4233f17-0e90-2860-e053-6605fe0a460a
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35
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Chemical characterization, antioxidant properties, anti-inflammatory activity, and enzyme inhibition of Ipomoea batatas L. leaf extracts, file e4233f16-8a9b-2860-e053-6605fe0a460a
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34
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Water extract from inflorescences of industrial hemp futura 75 variety as a source of anti-inflammatory, anti-proliferative and antimycotic agents: Results from in silico, in vitro and ex vivo studies, file e4233f17-a44e-2860-e053-6605fe0a460a
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29
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Anti-Candida activity and cytotoxicity of a large library of new N-substituted-1,3-thiazolidin-4-one derivatives, file e4233f19-2a3a-2860-e053-6605fe0a460a
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28
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Design, synthesis and biochemical evaluation of novel multi-target inhibitors as potential anti-Parkinson agents, file e4233f19-471b-2860-e053-6605fe0a460a
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28
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Kinesin Eg5 Selective Inhibition by Newly Synthesized Molecules as an Alternative Approach to Counteract Breast Cancer Progression: An In Vitro Study, file 7a46e2c9-900d-4f52-b808-dc1f7c3b7b89
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27
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Chemical constituents and biological activities of sage species: A comparison between Salvia officinalis L., S. glutinosa L. and S.transsylvanica (Schur ex Griseb. & Schenk) Schur, file e4233f17-9c09-2860-e053-6605fe0a460a
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27
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Dual carbonic anhydrase ix/xii inhibitors and carbon monoxide releasing molecules modulate LPS-mediated inflammation in mouse macrophages, file e4233f18-3e11-2860-e053-6605fe0a460a
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27
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Evaluation of processing effects on anthocyanin content and colour modifications of blueberry (Vaccinium spp.) extracts: Comparison between HPLC-DAD and CIELAB analyses, file e4233f19-277a-2860-e053-6605fe0a460a
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27
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Multiple pharmacognostic characterization on hemp commercial cultivars: Focus on inflorescence water extract activity, file e4233f17-0f72-2860-e053-6605fe0a460a
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26
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Antimicrobial and Antibiofilm Activities of New Synthesized Silver Ultra-NanoClusters (SUNCs) Against Helicobacter pylori, file e4233f17-d51a-2860-e053-6605fe0a460a
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26
|
Dual Acting Carbon Monoxide Releasing Molecules and Carbonic Anhydrase Inhibitors Differentially Modulate Inflammation in Human Tenocytes, file e4233f18-4733-2860-e053-6605fe0a460a
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26
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Resveratrol Analogues as Dual Inhibitors of Monoamine Oxidase B and Carbonic Anhydrase VII: A New Multi-Target Combination for Neurodegenerative Diseases?, file 563604aa-e6ca-4590-ab76-c2a640d8c23d
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25
|
4-(3-Nitrophenyl)thiazol-2-ylhydrazone derivatives as antioxidants and selective hMAO-B inhibitors: synthesis, biological activity and computational analysis, file e4233f17-0f18-2860-e053-6605fe0a460a
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25
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Screening of Benzimidazole-Based Anthelmintics and Their Enantiomers as Repurposed Drug Candidates in Cancer Therapy, file e4233f18-90a1-2860-e053-6605fe0a460a
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25
|
Phytocomplex Characterization and Biological Evaluation of Powdered Fruits and Leaves from Elaeagnus angustifolia, file e4233f17-8ee3-2860-e053-6605fe0a460a
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24
|
Use of innovative (micro)extraction techniques to characterize Harpagophytum procumbens root and its commercial food supplements, file e4233f19-7740-2860-e053-6605fe0a460a
|
24
|
Bioactive compounds of Crocus sativus L. and their semi-synthetic derivatives as promising anti-Helicobacter pylori, anti-malarial and anti-leishmanial agents, file e4233f15-ae71-2860-e053-6605fe0a460a
|
23
|
Chromatographic analyses, in vitro biological activities and cytotoxicity of Cannabis sativa L. essential oil: a multidisciplinary study, file e4233f17-049f-2860-e053-6605fe0a460a
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23
|
The Up-Regulation of Oxidative Stress as a Potential Mechanism of Novel MAO-B Inhibitors for Glioblastoma Treatment, file e4233f17-1e09-2860-e053-6605fe0a460a
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22
|
The Benzimidazole-Based Anthelmintic Parbendazole: A Repurposed Drug Candidate That Synergizes with Gemcitabine in Pancreatic Cancer, file e4233f17-5d24-2860-e053-6605fe0a460a
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22
|
Characterization of arils juice and peel decoction of fifteen varieties of punica Granatum L.: A focus on anthocyanins, ellagitannins and polysaccharides, file e4233f17-82a6-2860-e053-6605fe0a460a
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22
|
Synthesis, cytotoxicity and anti−proliferative activity against ags cells of new 3(2h)−pyridazinone derivatives endowed with a piperazinyl linker, file e4233f18-75e2-2860-e053-6605fe0a460a
|
22
|
Novel Biologically Active Molecules, Biomaterials, and Nanoparticles for Microbial Biofilm Control in Human Medicine, file e4233f18-bcb6-2860-e053-6605fe0a460a
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22
|
Cannabis sativa L. inflorescences from monoecious cultivars grown in Central Italy: an untargeted chemical characterization from early flowering to ripening, file e4233f17-7a85-2860-e053-6605fe0a460a
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21
|
Fibrate-based N-acylsulphonamides targeting carbonic anhydrases: synthesis, biochemical evaluation, and docking studies, file e4233f18-7444-2860-e053-6605fe0a460a
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21
|
Design, synthesis, docking studies and monoamine oxidase inhibition of a small library of 1-acetyl- and 1-thiocarbamoyl-3,5-diphenyl-4,5-dihydro-(1h)-pyrazoles, file e4233f17-0f1a-2860-e053-6605fe0a460a
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20
|
Characterization and Valorization of ‘Sulmona Red Garlic’ Peels and Small Bulbs, file 983621ce-a0af-4219-9cca-e633752e3797
|
19
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Negative Modulation of the Angiogenic Cascade Induced by Allosteric Kinesin Eg5 Inhibitors in a Gastric Adenocarcinoma In Vitro Model, file e4233f19-1b5a-2860-e053-6605fe0a460a
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19
|
Benzenesulfonamide derivatives as Vibrio cholerae carbonic anhydrases inhibitors: a computational-aided insight in the structural rigidity-activity relationships, file d1e1cf4e-7528-4fc9-9003-5c2ae83364a7
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18
|
Elucidation of the mechanisms governing the thermal diastereomerization of bioactive chiral 1,3,4-thiadiazoline spiro-cyclohexyl derivatives towards their anancomeric stereoisomers, file e4233f15-adf1-2860-e053-6605fe0a460a
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18
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A Comparative Assessment of Biological Effects and Chemical Profile of Italian Asphodeline lutea Extracts, file e4233f16-9ac2-2860-e053-6605fe0a460a
|
18
|
Are there any therapeutic options currently available for Wuhan coronavirus?, file e4233f18-037f-2860-e053-6605fe0a460a
|
18
|
Pomegranate Fruit Cracking during Maturation: From Waste to Valuable Fruits, file 9b17b61b-fc21-45a6-80ab-0f40db5ed7ee
|
17
|
Polyphenols from Lycium barbarum (Goji) Fruit European Cultivars at Different Maturation Steps: Extraction, HPLC-DAD Analyses, and Biological Evaluation, file e4233f17-509b-2860-e053-6605fe0a460a
|
17
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Novel insights on saccharin- and acesulfame-based carbonic anhydrase inhibitors: design, synthesis, modelling investigations and biological activity evaluation, file e4233f17-e70e-2860-e053-6605fe0a460a
|
17
|
Metabolomic profile and antioxidant/anti-inflammatory effects of industrial hemp water extract in fibroblasts, keratinocytes and isolated mouse skin specimens, file e4233f18-3836-2860-e053-6605fe0a460a
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17
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Biological investigation of N-methyl thiosemicarbazones as antimicrobial agents and bacterial carbonic anhydrases inhibitors, file e4233f19-3a09-2860-e053-6605fe0a460a
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17
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In Vitro Activity of the Arylaminoartemisinin GC012 against Helicobacter pylori and Its Effects on Biofilm, file e4233f19-7566-2860-e053-6605fe0a460a
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17
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Correlation between the antimicrobial activity and metabolic profiles of cell free supernatants and membrane vesicles produced by lactobacillus reuteri DSM 17938, file e4233f18-0a2e-2860-e053-6605fe0a460a
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16
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Synthesis and biological evaluation of carvacrol-based derivatives as dual inhibitors of H. Pylori strains and ags cell proliferation, file e4233f18-20a7-2860-e053-6605fe0a460a
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16
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Synthesis and Evaluation of Thymol-Based Synthetic Derivatives as Dual-Action Inhibitors against Different Strains of H. pylori and AGS Cell Line, file e4233f18-804d-2860-e053-6605fe0a460a
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16
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Drug repurposing, an attractive strategy in pancreatic cancer treatment: Preclinical and clinical updates, file e4233f18-97d7-2860-e053-6605fe0a460a
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16
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Antimicrobial and Antibiofilm Activities of Carvacrol, Amoxicillin and Salicylhydroxamic Acid Alone and in Combination vs. Helicobacter pylori: Towards a New Multi-Targeted Therapy, file b599f5c0-4225-4261-b3a2-3213af9d84bd
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15
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Optimization of Aqueous Extraction and Biological Activity of Harpagophytum procumbens Root on Ex Vivo Rat Colon Inflammatory Model, file e4233f16-3916-2860-e053-6605fe0a460a
|
15
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Identification of new anti-Candida compounds by ligand-based pharmacophore virtual screening, file e4233f15-b510-2860-e053-6605fe0a460a
|
14
|
Curcumin: Total-Scale Analysis of the Scientific Literature, file e4233f17-176f-2860-e053-6605fe0a460a
|
14
|
Kinesin Eg5 targeting inhibitors as a new strategy for gastric adenocarcinoma treatment, file e4233f17-5b7b-2860-e053-6605fe0a460a
|
14
|
Inhibition of lysine acetyltransferases impairs tumor angiogenesis acting on both endothelial and tumor cells, file e4233f17-9d04-2860-e053-6605fe0a460a
|
14
|
Phenylsulfonimide PPARα Antagonists Enhance Nrf2 Activation and Promote Oxidative Stress-Induced Apoptosis/Pyroptosis in MCF7 Breast Cancer Cells, file 62990d7b-7ac7-4e57-bfc3-b658f14ada32
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13
|
Graminex pollen: phenolic pattern, colorimetric analysis and protective effects in immortalized prostate cells (PC3) and rat prostate challenged with LPS, file e4233f16-ce36-2860-e053-6605fe0a460a
|
13
|
Chemical and bioinformatics analyses of the anti-leishmanial and anti-oxidant activities of hemp essential oil, file e4233f18-4120-2860-e053-6605fe0a460a
|
13
|
Carbonic Anhydrases: New Perspectives on Protein Functional Role and Inhibition in Helicobacter pylori, file e4233f18-7dbe-2860-e053-6605fe0a460a
|
13
|
Relevance of Cellular Redox Homeostasis for Vital Functions of Human Dental Pulp Cells, file e4233f18-e2e2-2860-e053-6605fe0a460a
|
13
|
Multiple pharmacognostic characterization on hemp commercial cultivars: Focus on inflorescence water extract activity, file e4233f18-ef77-2860-e053-6605fe0a460a
|
13
|
Optimization of Aqueous Extraction and Biological Activity of Harpagophytum procumbens Root on Ex Vivo Rat Colon Inflammatory Model, file e4233f19-3596-2860-e053-6605fe0a460a
|
13
|
Crocus sativus, Serenoa repens and Pinus massoniana extracts modulate inflammatory response in isolated rat prostate challenged with LPS, file e4233f16-4e67-2860-e053-6605fe0a460a
|
12
|
Optimization of ultrasonic extraction to obtain erinacine a and polyphenols with antioxidant activity from the fungal biomass of hericium erinaceus, file e4233f18-51d5-2860-e053-6605fe0a460a
|
12
|
New azolyl-derivatives as multitargeting agents against breast cancer and fungal infections: synthesis, biological evaluation and docking study, file e4233f18-7ec0-2860-e053-6605fe0a460a
|
12
|
Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells, file e4233f15-b216-2860-e053-6605fe0a460a
|
11
|
Commercial hemp seed oils: A multimethodological characterization, file e4233f18-0292-2860-e053-6605fe0a460a
|
11
|
Amine-and amino acid-based compounds as carbonic anhydrase activators, file e4233f18-894c-2860-e053-6605fe0a460a
|
11
|
Anti-diabetic and anti-hyperlipidemic properties of Capparis spinosa L.: In vivo and in vitro evaluation of its nutraceutical potential, file e4233f18-fb92-2860-e053-6605fe0a460a
|
11
|
Inhibition of Schistosoma mansoni carbonic anhydrase by the antiparasitic drug clorsulon: X-ray crystallographic and in vitro studies, file e4233f19-0346-2860-e053-6605fe0a460a
|
11
|
Novel 1,3-thiazolidin-4-one derivatives as promising anti-Candida agents endowed with anti-oxidant and chelating properties, file e4233f19-4716-2860-e053-6605fe0a460a
|
11
|
Crocus sativus L. stigmas and byproducts: Qualitative fingerprint, antioxidant potentials and enzyme inhibitory activities, file e4233f16-cd3c-2860-e053-6605fe0a460a
|
10
|
Azole-Based Compounds That Are Active against Candida Biofilm: In Vitro, In Vivo and In Silico Studies, file 316c5ae3-b0ae-4272-be99-c90e84200fce
|
9
|
Natural and Synthetic Xanthone Derivatives Counteract Oxidative Stress via Nrf2 Modulation in Inflamed Human Macrophages, file 8b642a7a-742b-4f66-9ad3-8c0705b6e4ff
|
8
|
Anti-diabetic and anti-hyperlipidemic properties of Capparis spinosa L.: In vivo and in vitro evaluation of its nutraceutical potential, file e4233f15-fca1-2860-e053-6605fe0a460a
|
8
|
Saffron Samples of Different Origin: An NMR Study of Microwave-Assisted Extracts, file e4233f16-728e-2860-e053-6605fe0a460a
|
8
|
Innovative Extraction Techniques and Hyphenated Instrument Configuration for Complex Matrices Analysis, file e4233f16-ed0d-2860-e053-6605fe0a460a
|
8
|
Antibiofilm activity and NMR-based metabolomic characterization of cell-free supernatant of Limosilactobacillus reuteri DSM 17938, file 26b1efab-fb5a-477a-9ba8-bcc00e7dca62
|
7
|
Novel Insights on Human Carbonic Anhydrase Inhibitors Based on Coumalic Acid: Design, Synthesis, Molecular Modeling Investigation, and Biological Studies, file 4d38bf4e-bfe9-4c53-9cb7-9715beefcfb0
|
7
|
Design, Synthesis and Biological Assessment of Rhodanine-Linked Benzenesulfonamide Derivatives as Selective and Potent Human Carbonic Anhydrase Inhibitors, file 77ca580a-c8d7-498a-a535-f9196ee6120d
|
7
|
Development of novel techniques to extract phenolic compounds from Romanian cultivars of Prunus domestica L. and their biological properties, file e4233f16-ddb2-2860-e053-6605fe0a460a
|
7
|
A novel class of dual-acting DCH-CORMs counteracts oxidative stress-induced inflammation in human primary tenocytes, file e4233f18-9bc7-2860-e053-6605fe0a460a
|
7
|
Nature as a source and inspiration for human monoamine oxidase B (hMAO-B) inhibition: A review of the recent advances in chemical modification of natural compounds, file a16a941a-c106-4068-88cc-bba5a87ddbd4
|
6
|
Bioactive compounds of Crocus sativus L. and their semi-synthetic derivatives as promising anti-Helicobacter pylori, anti-malarial and anti-leishmanial agents, file e4233f18-925c-2860-e053-6605fe0a460a
|
6
|
Hericium erinaceus (Bull.) Pers. Ethanolic Extract with Antioxidant Properties on Scopolamine-Induced Memory Deficits in a Zebrafish Model of Cognitive Impairment, file e4233f18-b3b9-2860-e053-6605fe0a460a
|
6
|
Modulatory Properties of Food and Nutraceutical Components Targeting NLRP3 Inflammasome Activation, file e4233f18-d4d6-2860-e053-6605fe0a460a
|
6
|
Crocus sativus L. stigmas and byproducts: Qualitative fingerprint, antioxidant potentials and enzyme inhibitory activities, file e4233f19-25be-2860-e053-6605fe0a460a
|
6
|
Totale |
3.126 |