Abstract—Aminoethylcysteineketiminedecarboxylateddimer(2)isanaturalsulfurcompoundwithantioxidantproperties. 2 Inhibitssome reactionsmediatedbyperoxynitrite,astrongoxidizingandnitratingagentthatreactswithseveralbiomolecules.Thisworkaimstoelucidate thestructureoftheproductresultingfromtheinteractionof 2 withperoxynitriteusing1Dand2DNMRexperimentsandiontrapmass spectrometry.Thisproductisadimerizedformof 2 andishereafterreferredtoas 3.Duringthereactionsleadingto 2 andduringthe formationof 3,nochiralselectionisoperated;allopticalisomersarepresentinD2Oandhavebeenevidencedby 1 HNMRmethodsinD2O plus b-or g-cyclodextrin.
Titolo: | Structural elucidation of the oxidation product of aminoethylcysteine ketimine decarboxylated dimmer by peroxynitrite | |
Autori: | ||
Data di pubblicazione: | 2004 | |
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Abstract: | Abstract—Aminoethylcysteineketiminedecarboxylateddimer(2)isanaturalsulfurcompoundwithantioxidantproperties. 2 Inhibitssome reactionsmediatedbyperoxynitrite,astrongoxidizingandnitratingagentthatreactswithseveralbiomolecules.Thisworkaimstoelucidate thestructureoftheproductresultingfromtheinteractionof 2 withperoxynitriteusing1Dand2DNMRexperimentsandiontrapmass spectrometry.Thisproductisadimerizedformof 2 andishereafterreferredtoas 3.Duringthereactionsleadingto 2 andduringthe formationof 3,nochiralselectionisoperated;allopticalisomersarepresentinD2Oandhavebeenevidencedby 1 HNMRmethodsinD2O plus b-or g-cyclodextrin. | |
Handle: | http://hdl.handle.net/11564/115162 | |
Appare nelle tipologie: | 1.1 Articolo in rivista |