Abstract—Aminoethylcysteineketiminedecarboxylateddimer(2)isanaturalsulfurcompoundwithantioxidantproperties. 2 Inhibitssome reactionsmediatedbyperoxynitrite,astrongoxidizingandnitratingagentthatreactswithseveralbiomolecules.Thisworkaimstoelucidate thestructureoftheproductresultingfromtheinteractionof 2 withperoxynitriteusing1Dand2DNMRexperimentsandiontrapmass spectrometry.Thisproductisadimerizedformof 2 andishereafterreferredtoas 3.Duringthereactionsleadingto 2 andduringthe formationof 3,nochiralselectionisoperated;allopticalisomersarepresentinD2Oandhavebeenevidencedby 1 HNMRmethodsinD2O plus b-or g-cyclodextrin.

Structural elucidation of the oxidation product of aminoethylcysteine ketimine decarboxylated dimmer by peroxynitrite

PINNEN, Francesco Enrico;
2004

Abstract

Abstract—Aminoethylcysteineketiminedecarboxylateddimer(2)isanaturalsulfurcompoundwithantioxidantproperties. 2 Inhibitssome reactionsmediatedbyperoxynitrite,astrongoxidizingandnitratingagentthatreactswithseveralbiomolecules.Thisworkaimstoelucidate thestructureoftheproductresultingfromtheinteractionof 2 withperoxynitriteusing1Dand2DNMRexperimentsandiontrapmass spectrometry.Thisproductisadimerizedformof 2 andishereafterreferredtoas 3.Duringthereactionsleadingto 2 andduringthe formationof 3,nochiralselectionisoperated;allopticalisomersarepresentinD2Oandhavebeenevidencedby 1 HNMRmethodsinD2O plus b-or g-cyclodextrin.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11564/115162
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