Pancreaticoduodenectomy for Infiltrative Duodenal Gastrointestinal Stromal Tumor Mimicking Pancreatic Head Neoplasm

This is the first case of duodenal GIST which was assessed as a pancreatic head tumor, successfully treated with pancreaticoduodenectomy. Endoscopy may be diagnostic in duodenal GIST, especially for well-defined tumor with centrally ulcerated umbilication. This was not the case. Unfortunately, the lesion did not show the typical radiological and endoscopic pattern. The present case underlines the difficulties of a correct preoperative diagnosis in such uncommon clinical condition where infiltrative duodenal GIST might mimic a pancreatic head tumor.