Utilizza questo identificativo per citare o creare un link a questo documento:
|Titolo:||Nitrates in cardiology: current role and areas of uncertainty|
|Autori interni:||DE CATERINA, Raffaele|
|Data di pubblicazione:||2011|
|Rivista:||GIORNALE ITALIANO DI CARDIOLOGIA|
|Abstract:||Nitrates have been commonly used in the therapy of cardiovascular disease for more than 150 years. In spite of this longevity and the popularity of their use, it appears somewhat paradoxical that their use is not consistent among cardiologists, both as to their indications and as to their mode of administration. In part this results from their contradictory pharmacodynamics: when given acutely, their effectiveness is indisputable; however, their long-term efficacy is substantially limited by the development of tolerance and the induction of endothelial dysfunction, which may have negative prognostic implications. This review, reporting the most recent biochemical and pathophysiological acquisitions, re-examines the role of nitrates in cardiovascular medicine, reporting, comparing and commenting international guidelines.|
|Appare nelle tipologie:||1.1 Articolo in rivista|
File in questo prodotto:
Non ci sono file associati a questo prodotto.
- PubMed Central loading...
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.