Common bean (Phaseolus vulgaris) represents one of the most famous food with anti-obesity ac-tivity showing a significant efficacy against fat accumulation, insulin resistance and dyslipidae-mia. In this work two Italian verieties of common bean e.g. Tondino del Tavo and Cannellino Bio from the centre of Italy were studied to characterise their phenolic profile by HPLC-PDA in relation to different fractions after a straightforward extraction procedure. Antioxidant property and enzymatic inhibition power were also evaluated in order to delineate a possible biological profile. Results show a considerable phenolic content (0.79 and 1.1 µg/mg of 3-hydroxy benzoic acid for hexane extract of Tondino del Tavo and Cannellino Bio respectively; 0.30 µg/mg p-coumaric acid for n-hexane extract of Tondino del Tavo) for both varieties, and a strong anti-oxidant activity according to the major phenolic concentration of the extracts. An-ti-inflammatory activity of the decoction extracts was also investigated through zymo-san-induced edema formation assay, revealing a moderate ability for both of them to reduce the edema formation. These preliminary data prompt us to further explore the nutrient components of these two varieties in the next future.

A Comparative Study on Phytochemical Fingerprint of Two Diverse Phaseolus vulgarisvar. Tondino del Tavo and Cannellino Bio Extracts

Azzurra Stefanucci
;
Giuseppe Scioli;Lorenza Marinaccio;Marcello Locatelli;Angela Tartaglia;Alice Della Valle;Angelo Cichelli;Adriano Mollica
2022-01-01

Abstract

Common bean (Phaseolus vulgaris) represents one of the most famous food with anti-obesity ac-tivity showing a significant efficacy against fat accumulation, insulin resistance and dyslipidae-mia. In this work two Italian verieties of common bean e.g. Tondino del Tavo and Cannellino Bio from the centre of Italy were studied to characterise their phenolic profile by HPLC-PDA in relation to different fractions after a straightforward extraction procedure. Antioxidant property and enzymatic inhibition power were also evaluated in order to delineate a possible biological profile. Results show a considerable phenolic content (0.79 and 1.1 µg/mg of 3-hydroxy benzoic acid for hexane extract of Tondino del Tavo and Cannellino Bio respectively; 0.30 µg/mg p-coumaric acid for n-hexane extract of Tondino del Tavo) for both varieties, and a strong anti-oxidant activity according to the major phenolic concentration of the extracts. An-ti-inflammatory activity of the decoction extracts was also investigated through zymo-san-induced edema formation assay, revealing a moderate ability for both of them to reduce the edema formation. These preliminary data prompt us to further explore the nutrient components of these two varieties in the next future.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11564/788491
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