Common bean (Phaseolus vulgaris) represents one of the most famous food with anti-obesity ac-tivity showing a significant efficacy against fat accumulation, insulin resistance and dyslipidae-mia. In this work two Italian verieties of common bean e.g. Tondino del Tavo and Cannellino Bio from the centre of Italy were studied to characterise their phenolic profile by HPLC-PDA in relation to different fractions after a straightforward extraction procedure. Antioxidant property and enzymatic inhibition power were also evaluated in order to delineate a possible biological profile. Results show a considerable phenolic content (0.79 and 1.1 µg/mg of 3-hydroxy benzoic acid for hexane extract of Tondino del Tavo and Cannellino Bio respectively; 0.30 µg/mg p-coumaric acid for n-hexane extract of Tondino del Tavo) for both varieties, and a strong anti-oxidant activity according to the major phenolic concentration of the extracts. An-ti-inflammatory activity of the decoction extracts was also investigated through zymo-san-induced edema formation assay, revealing a moderate ability for both of them to reduce the edema formation. These preliminary data prompt us to further explore the nutrient components of these two varieties in the next future.

A Comparative Study on Phytochemical Fingerprint of Two Diverse Phaseolus vulgarisvar. Tondino del Tavo and Cannellino Bio Extracts

Azzurra Stefanucci
;
Giuseppe Scioli;Lorenza Marinaccio;Marcello Locatelli;Angela Tartaglia;Alice Della Valle;Angelo Cichelli;Adriano Mollica
2022-01-01

Abstract

Common bean (Phaseolus vulgaris) represents one of the most famous food with anti-obesity ac-tivity showing a significant efficacy against fat accumulation, insulin resistance and dyslipidae-mia. In this work two Italian verieties of common bean e.g. Tondino del Tavo and Cannellino Bio from the centre of Italy were studied to characterise their phenolic profile by HPLC-PDA in relation to different fractions after a straightforward extraction procedure. Antioxidant property and enzymatic inhibition power were also evaluated in order to delineate a possible biological profile. Results show a considerable phenolic content (0.79 and 1.1 µg/mg of 3-hydroxy benzoic acid for hexane extract of Tondino del Tavo and Cannellino Bio respectively; 0.30 µg/mg p-coumaric acid for n-hexane extract of Tondino del Tavo) for both varieties, and a strong anti-oxidant activity according to the major phenolic concentration of the extracts. An-ti-inflammatory activity of the decoction extracts was also investigated through zymo-san-induced edema formation assay, revealing a moderate ability for both of them to reduce the edema formation. These preliminary data prompt us to further explore the nutrient components of these two varieties in the next future.
File in questo prodotto:
File Dimensione Formato  
antioxidants-1828602.pdf

accesso aperto

Tipologia: Documento in Post-print
Dimensione 597.53 kB
Formato Adobe PDF
597.53 kB Adobe PDF Visualizza/Apri
antioxidants-11-01474.pdf

accesso aperto

Tipologia: PDF editoriale
Dimensione 1.14 MB
Formato Adobe PDF
1.14 MB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11564/788491
Citazioni
  • ???jsp.display-item.citation.pmc??? 2
  • Scopus ND
  • ???jsp.display-item.citation.isi??? 3
social impact