Background Dementia is a frequent disease in the elderly population, and its prevalence is still increasing worldwide. Among subjects discharged from general hospitals, thepercentage of patient with dementia vary between 4 and 30%. Dementia is generally associated with higher rate of admission to hospital, increased length of hospitalization, and with an increased risk in postadmission mortality. The aim of this study was to evaluate the impact of dementia on in-hospital mortality and length of stay (LOS) in an Italian Southern Region. Methods Data related to hospital admissions were extracted from the hospital discharge record of the Abruzzo region, considering all admissions performed during the years 2015–2021. Dementia and all comorbidities included in Charlson Comorbidity index (CCI) were extracted. Prolonged LOS was defined as a duration beyond 10 days, representing the upper quartile of distribution. Factors associated to in-hospital mortality and prolonged LOS were estimated with multivariable logistic regression models adjusted for age, sex and CCI diseases. Results During the study period, 3355 admissions ofpatients with dementia were performed, over atotal of 1,197,381. Logistic regression analysesshowed as dementia disease was associated with in-hospital mortality (OR: 2.69 IC95%2.43-2.98) and prolonged LOS (OR: 1.72; IC95% 1.59-1.86). Conclusions In a cohort of Italian patients, subjects with dementia were associated with in-hospital mortality and prolonged LOS.
The impact of dementia on in-hospital mortality and prolonged length of stay
Di Martino G.
Primo
;Scampoli P.;Di Giovanni P.;Cedrone F.;Staniscia T.
2024-01-01
Abstract
Background Dementia is a frequent disease in the elderly population, and its prevalence is still increasing worldwide. Among subjects discharged from general hospitals, thepercentage of patient with dementia vary between 4 and 30%. Dementia is generally associated with higher rate of admission to hospital, increased length of hospitalization, and with an increased risk in postadmission mortality. The aim of this study was to evaluate the impact of dementia on in-hospital mortality and length of stay (LOS) in an Italian Southern Region. Methods Data related to hospital admissions were extracted from the hospital discharge record of the Abruzzo region, considering all admissions performed during the years 2015–2021. Dementia and all comorbidities included in Charlson Comorbidity index (CCI) were extracted. Prolonged LOS was defined as a duration beyond 10 days, representing the upper quartile of distribution. Factors associated to in-hospital mortality and prolonged LOS were estimated with multivariable logistic regression models adjusted for age, sex and CCI diseases. Results During the study period, 3355 admissions ofpatients with dementia were performed, over atotal of 1,197,381. Logistic regression analysesshowed as dementia disease was associated with in-hospital mortality (OR: 2.69 IC95%2.43-2.98) and prolonged LOS (OR: 1.72; IC95% 1.59-1.86). Conclusions In a cohort of Italian patients, subjects with dementia were associated with in-hospital mortality and prolonged LOS.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
