Lymphedema and psychosocial well-being: a mixed-methods exploration of resources and challenges in the Italian context.

Abstract Introduction. Individuals affected by lymphedema, both primary and secondary, experience a significant reduction in quality of life and functional capacity. However, the impact of lymphedema on occupational life, specifically on return-to-work processes, remains largely unexplored. Objectives. This study explores the psychosocial, occupational, and health-related challenges experienced by individuals with lymphedema, with a focus on work reintegration. Methods. A mixed-method approach was adopted through the development of an online survey, which included both standardized psychometric scales and open-ended questions. Results. The mediation analysis confirmed that return to work self-efficacy serves as a key mechanism through which optimism contributes to job satisfaction. Qualitative findings highlight the need for multilevel and systemic interventions. From an individual perspective, targeted self-efficacy training programs for workers with lymphedema appear crucial. Conclusions. Considering a community and an organizational perspective, it is essential to implement training initiatives for healthcare professionals aimed at improving their knowledge and awareness of lymphedema.