IRIS
SOZIO, Piera
 Distribuzione geografica
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Continente #
NA - Nord America 2.090
EU - Europa 2.041
AS - Asia 1.009
SA - Sud America 5
Continente sconosciuto - Info sul continente non disponibili 4
Totale 5.149
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Nazione #
US - Stati Uniti d'America 2.084
CN - Cina 407
UA - Ucraina 379
IT - Italia 319
IE - Irlanda 316
GB - Regno Unito 283
SG - Singapore 239
SE - Svezia 238
FR - Francia 223
TR - Turchia 222
IN - India 123
DE - Germania 110
FI - Finlandia 74
RU - Federazione Russa 49
CZ - Repubblica Ceca 18
IR - Iran 11
BE - Belgio 9
PL - Polonia 7
ES - Italia 6
CA - Canada 4
EU - Europa 4
BR - Brasile 3
GR - Grecia 3
HK - Hong Kong 2
HU - Ungheria 2
VN - Vietnam 2
AL - Albania 1
AR - Argentina 1
AT - Austria 1
CH - Svizzera 1
CL - Cile 1
IL - Israele 1
JP - Giappone 1
KR - Corea 1
MX - Messico 1
PA - Panama 1
PT - Portogallo 1
RO - Romania 1
Totale 5.149
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Città #
Chandler 415
Jacksonville 413
Dublin 312
Southend 244
Singapore 220
Princeton 138
Nanjing 124
Izmir 116
Chieti 98
Dearborn 94
Ashburn 90
Cambridge 69
Wilmington 66
Ann Arbor 59
Altamura 55
Santa Clara 54
Nanchang 44
Beijing 42
Boardman 35
Shenyang 31
Tianjin 24
Washington 24
Kunming 21
Kocaeli 20
New York 19
Brno 18
Woodbridge 18
Jiaxing 16
Grevenbroich 15
Hebei 15
Los Angeles 14
Jinan 13
Leawood 13
Ningbo 13
Zhengzhou 13
Augusta 12
Pescara 10
Ardabil 9
Brussels 9
Teramo 8
Auburn Hills 7
Guangzhou 7
Munich 7
Hangzhou 6
Helsinki 6
Kraków 6
San Mateo 6
Simi Valley 6
Falls Church 5
Lanzhou 5
Norwalk 5
Cepagatti 4
Changsha 4
Hefei 4
Houston 4
Monmouth Junction 4
Moscow 4
Naples 4
Orange 4
San Donato Milanese 4
Seattle 4
Sesena Nuevo 4
Silvi 4
Taizhou 4
Tappahannock 4
Changchun 3
Düsseldorf 3
Rovereto 3
Bangalore 2
Clifton 2
Dallas 2
Dong Ket 2
Haikou 2
Hong Kong 2
Isernia 2
Lanciano 2
Lucca 2
Messina 2
Milan 2
Mumbai 2
Orpington 2
Parma 2
San Salvo 2
Siena 2
Toronto 2
Ancona 1
Aquila 1
Atatürk 1
Bellante 1
Bucharest 1
Budapest 1
Buffalo 1
Campomarino 1
Castel Di Sangro 1
Chengdu 1
Chicago 1
Chongqing 1
Collecorvino 1
Debrecen 1
Delhi 1
Totale 3.203
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Nome #
Viscoelastic properties of Staphylococcus aureus and Staphylococcus epidermidis mono-microbial biofilms 172
Synthesis of a novel cyclic prodrug of S -allyl-glutathione able to attenuate LPS-induced ROS production through the inhibition of MAPK pathways in U937 cells 128
Solid lipid nanoparticles loaded with lipoyl-memantine codrug: preparation and characterization 111
A glutathione derivative with chelating and in vitro neuroprotective activities: synthesis, physicochemical properties, and biological evaluation. 107
Synthesis and evaluation of trans-2-amino-5(or 6)-chloro-6(or 5)-hydroxy-1-phenyl-2,3-dihydro-1H-indenes as dopamine receptor ligands 105
Synthesis and preliminary pharmacological evaluation of 2,3,4,8,13a-hexahydro-1H-benzo(5,6)cyclohepta(1,2,3-ef)(3)benzazepine-6,7-diol derivatives as dopamine receptor ligands 101
(R)-α-Lipoyl-glycyl-L-prolyl-L-glutamyl dimethyl ester codrug as a multifunctional agent with potential neuroprotective activities 99
Antiparkinson Prodrugs 98
Characterization of alkanoyl-10-O-minocyclines in micellar dispersions as potential agents for treatment of human neurodegenerative disorders 96
Potential Antibacterial Activity of Carvacrol-Loaded PLGA Nanoparticles against Microbial Biofilm 96
Ibuprofen and glutathione conjugate as a potential therapeutic agent for treating Alzheimer's disease 95
Sintesi di trans-2-ammino-1-fenil-5-fluoro-6-idrossi (e 6-fluoro-5-idrossi)-2,3-diidro-1H-indeni quali potenziali ligandi per i recettori dopaminergici 92
CNS delivery of L-Dopa by a new Hybrid Glutathione-Methionine peptidomimetic prodrug 92
Synthesis and Study of L-Dopa-Glutathione Codrugs as New Anti-Parkinson Agents with Free Radical Scavenging Properties. 90
Synthesis and preliminary evaluation of L-dopa/benserazide conjugates as dual acting codrugs 90
L-Dopa Prodrugs: An Overview of Trends for Improving Parkinson's Disease Treatment 89
synthesis and Activity of L-Dopa-Thiol antioxidant Co-drugs and New anti-PArkinson Agents with free Radical Scavenging Properties 88
Design, synthesis and preliminary pharmacological evaluation of new imidazolinones as L-DOPA prodrugs. 87
Gold nanoparticles as scaffolds for new antiparkinson prodrugs 87
Maleic- and Fumaric-diamides of (O,O-diacetyl)-L-Dopa-methylester as anti-Parkinson prodrugs in liposomal formulation 86
Biodegradable microspheres loaded with an antiparkinson prodrug: an in vivo pharmacokinetic study 86
Synthesis and preliminary pharmacological evaluation of trans-2-amino-5(6)-chloro-6(5)-hydroxy-1- phenyl-2,3-dihydro-1H-indenes as dopamine receptor ligands 84
Synthesis and biological evaluation of a novel pyroglutamil-modified TRH analogue 83
synthesis and biological evaluation as anti-Parkinson agent of an analogue of Glutathione-L-Dopa containing methionine in place of the cysteinil residue 83
Ibuprofen and lipoic acid diamide as co-drugs with neuroprotective activity: pharmacological properties and effects in β-amyloid (1-40) infused Alzheimer’s disease rat model. 81
NOS-mediated morphological and molecular modifications in rats infused with Aβ (1-40), as a model of Alzheimer’s Disease, in response to a new lipophilic molecular combination codrug-1 81
Memantine-sulphur containing antioxidant conjugates as potential prodrugs to improve the treatment of Alzheimer’s disease 81
Transition state isosteres of the gamma-glutamyl peptide bond hydrolysis: synthesis and characterization of the psi (CH2NH) pseudopeptide analogue of glutathione 80
A new lipophilic molecular combination codrug-1 exerts neuroprotective activity in beta amyloid (1-40) infused Alzheimer’s disease rat model 79
Evaluation of 2,3,4,8,13a hexahydro-1H-Benzo[5,6]cyclohepta-6,7-dihydroxy[1,2,3-ef][3]benzazepine derivatives as dopamine receptor ligands 78
New drug delivery strategies for improved Parkinson’s disease therapy 78
Nuovi S-coniugati del glutatione ad attività inibitoria nei confronti delle GST umane 77
Preparation and pharmacological characterization of trans-2-amino-5(6)-fluoro-6(5)-hydroxy-1-phenyl-2,3-dihydro-1H-indenes as D2-like dopamine receptor agonists 77
Evaluation of rat striatal L-Dopa and DA concentration after intraperitoneal administration of L- Dopa prodrugs in liposomal formulations 76
Design and synthesis of multifunctional drugs: a strategy to improve the treatment of Parkinson’s disease 76
Glycosyl and polyalcoholic prodrugs of lonidamine 75
Ibuprofen and lipoic acid diamides as potential codrugs with neuroprotective activity 75
Codrugs Linking l-Dopa and Sulfur-Containing Antioxidants: New Pharmacological Tools against Parkinson’s Disease 75
Transdermal donepezil on the treatment of Alzheimer’s disease 74
Synthesis and activity of novel glutathione analogues containing an urethane backbone linkage 73
L-Dopa- and dopamine- (R)-α-lipoic acid conjugates as multifunctional codrugs with antioxidant properties 72
Detection of levodopa, dopamine and its metabolites in rat striatum dialysates following peripheral administration of L-DOPA prodrugs by mean of HPLC-EC 72
Designing Prodrugs for the Treatment of Parkinson's Disease 72
Drug Delivery Strategies for Alzheimer's Disease Treatment 71
New Flurbiprofen Derivatives: Synthesis, Membrane Affinity and Evaluation of in Vitro Effect on β-Amyloid Levels 71
Potent isozyme-selective inhibition of human glutathione S-transferase A1-1 by a novel glutathione S-conjugate 71
Ibuprofen and lipoic Acid conjugate neuroprotective activity is mediated by ngb/akt intracellular signaling pathway in Alzheimer's disease rat model 70
New L-Dopa codrugs as potential antiparkinson agents 66
Dimeric L-dopa derivatives as potential prodrugs. 65
Preparation and characterization of poly(lactic-co-glycolic acid) microspheres loaded with a labile antiparkinson prodrug 64
Haloperidol metabolite II prodrug: Asymmetric synthesis and biological evaluation on rat C6 glioma cells 64
Synthesis and biological evaluation of oligopeptides with antioxidant activity useful for treatment of neurodegenerative diseases 62
The Investigation of Cytogenetic and Oxidative Effects of Diffractaic Acid on Human Lymphocyte Cultures 62
Dopaminergic system modulation, behavioral changes, and oxidative stress after neonatal administration of pyrethroids 61
Effect of choline-containing phospholipids on brain cholinergic transporters in the rat. 61
Evaluation of cytotoxic, oxidative stress and genotoxic responses of hydroxyapatite nanoparticles on human blood cells 60
Ibuprofen-Glutathione Conjugate as Anti-inflammatory and Anti-apoptotic Agent in Rat Brain Infused with β Amyloid (1-40) 59
Effect of treatment with choline-contining Phospholipids on brain neurontransmitter transporters 58
Modulation of monoaminergic transporters by choline-containing phospholipids in rat brain 58
Novel O-palmitoylscleroglucan-coated liposomes as drug carriers: Development, characterization and interation with leuprolide 56
Multifuctional L-Dopa Codrugs Containing Antioxidant Molecules 56
pPKC alpha.mediated effect on in vitro AB production in response to gamma secretase inhibitor LY411575in rat CTXTNA2 astrocytes. 55
Protective effects of cyclosativene on H2O 2-induced injury in cultured rat primary cerebral cortex cells 55
Ibuprofen and lipoic acid codrug 1 control Alzheimer's disease progression by down - regulating Protein Kinase C ε – mediated Metalloproteinase 2 and 9 levels in β-amyloid infused Alzheimer's disease rat model 48
In vivo anti-apoptotic effect of compound 4 in rats infused with Abeta (1-40), as a model of Alzheimer's disease 43
In vivo anti-apoptotic effect of compound 4 in rats infused with Aβ (1-40), as a model of Alzheimer’s disease 40
Novel imidazoline compounds as partial or full agonists of D2-likedopamine receptors inspired by I2-imidazoline binding sites ligand 2-BFI 39
Lipid nanocarriers containing a levodopa prodrug with potential antiparkinsonian activity 38
Neuroprotective effects of farnesene against hydrogen peroxide-induced neurotoxicity in vitro 28
Totale 5.278
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Categoria #
all - tutte 18.856
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 18.856
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020602 0 0 4 33 71 82 135 94 16 71 87 9
2020/2021483 72 3 71 4 50 83 9 7 20 80 67 17
2021/2022306 5 7 6 44 29 7 7 25 45 17 32 82
2022/20231.096 79 171 62 129 94 229 54 91 122 17 24 24
2023/2024493 35 23 43 12 37 152 125 4 5 5 1 51
2024/2025452 65 223 164 0 0 0 0 0 0 0 0 0
Totale 5.278