IRIS
SOZIO, Piera
 Distribuzione geografica
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Continente #
NA - Nord America 2.732
EU - Europa 2.266
AS - Asia 1.804
SA - Sud America 171
AF - Africa 21
Continente sconosciuto - Info sul continente non disponibili 4
Totale 6.998
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Nazione #
US - Stati Uniti d'America 2.681
SG - Singapore 665
CN - Cina 641
UA - Ucraina 383
IT - Italia 330
GB - Regno Unito 329
IE - Irlanda 316
FR - Francia 251
SE - Svezia 242
TR - Turchia 226
DE - Germania 169
BR - Brasile 154
IN - India 142
FI - Finlandia 89
VN - Vietnam 53
RU - Federazione Russa 52
CA - Canada 34
BE - Belgio 23
PL - Polonia 22
CZ - Repubblica Ceca 18
ES - Italia 16
HK - Hong Kong 14
BD - Bangladesh 13
ZA - Sudafrica 12
IR - Iran 11
LT - Lituania 11
MX - Messico 10
AR - Argentina 9
KR - Corea 9
IQ - Iraq 7
ID - Indonesia 6
JP - Giappone 6
EU - Europa 4
TN - Tunisia 4
GR - Grecia 3
KE - Kenya 3
PE - Perù 3
AL - Albania 2
CL - Cile 2
CR - Costa Rica 2
HU - Ungheria 2
IL - Israele 2
PK - Pakistan 2
PY - Paraguay 2
RO - Romania 2
SA - Arabia Saudita 2
UZ - Uzbekistan 2
AM - Armenia 1
AT - Austria 1
AZ - Azerbaigian 1
BB - Barbados 1
BG - Bulgaria 1
CG - Congo 1
CH - Svizzera 1
CO - Colombia 1
DO - Repubblica Dominicana 1
EE - Estonia 1
GD - Grenada 1
MA - Marocco 1
NL - Olanda 1
NP - Nepal 1
PA - Panama 1
PT - Portogallo 1
TT - Trinidad e Tobago 1
Totale 6.998
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Città #
Singapore 529
Chandler 415
Jacksonville 413
Dublin 312
Southend 244
Ashburn 166
Beijing 143
Princeton 138
Dallas 128
Nanjing 124
Izmir 116
Chieti 99
Dearborn 94
Cambridge 69
Los Angeles 66
Wilmington 66
Santa Clara 64
Ann Arbor 59
The Dalles 56
Altamura 55
Tongling 54
Munich 48
New York 48
Nanchang 44
Boardman 35
Shenyang 31
Buffalo 28
Washington 25
Tianjin 24
Brussels 23
Kunming 22
Kocaeli 20
Ho Chi Minh City 19
Brno 18
Woodbridge 18
Jiaxing 16
Grevenbroich 15
Hebei 15
Montreal 15
São Paulo 15
Hong Kong 14
Ningbo 14
Jinan 13
Leawood 13
Zhengzhou 13
Augusta 12
Frankfurt am Main 12
Hefei 12
Helsinki 12
Redondo Beach 12
Warsaw 12
Brooklyn 10
Hanoi 10
Johannesburg 10
London 10
Pescara 10
Toronto 10
Ardabil 9
Boston 9
Turku 9
Bexley 8
Chennai 8
Houston 8
Seoul 8
Teramo 8
Atlanta 7
Auburn Hills 7
Denver 7
Guangzhou 7
Orem 7
Poplar 7
Seattle 7
Hangzhou 6
Kraków 6
Milan 6
Naples 6
San Mateo 6
Simi Valley 6
Tokyo 6
West Jordan 6
Chicago 5
Dhaka 5
Falls Church 5
Guarulhos 5
Haiphong 5
Lanzhou 5
Mexico City 5
Mumbai 5
Norwalk 5
Ottawa 5
Porto Alegre 5
Cepagatti 4
Changchun 4
Changsha 4
Monmouth Junction 4
Moscow 4
Nuremberg 4
Orange 4
Phoenix 4
San Donato Milanese 4
Totale 4.343
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Nome #
Viscoelastic properties of Staphylococcus aureus and Staphylococcus epidermidis mono-microbial biofilms 211
(R)-α-Lipoyl-glycyl-L-prolyl-L-glutamyl dimethyl ester codrug as a multifunctional agent with potential neuroprotective activities 168
A glutathione derivative with chelating and in vitro neuroprotective activities: synthesis, physicochemical properties, and biological evaluation. 151
Synthesis of a novel cyclic prodrug of S -allyl-glutathione able to attenuate LPS-induced ROS production through the inhibition of MAPK pathways in U937 cells 149
Solid lipid nanoparticles loaded with lipoyl-memantine codrug: preparation and characterization 143
CNS delivery of L-Dopa by a new Hybrid Glutathione-Methionine peptidomimetic prodrug 134
Potential Antibacterial Activity of Carvacrol-Loaded PLGA Nanoparticles against Microbial Biofilm 134
Synthesis and preliminary pharmacological evaluation of 2,3,4,8,13a-hexahydro-1H-benzo(5,6)cyclohepta(1,2,3-ef)(3)benzazepine-6,7-diol derivatives as dopamine receptor ligands 130
Synthesis and evaluation of trans-2-amino-5(or 6)-chloro-6(or 5)-hydroxy-1-phenyl-2,3-dihydro-1H-indenes as dopamine receptor ligands 126
Characterization of alkanoyl-10-O-minocyclines in micellar dispersions as potential agents for treatment of human neurodegenerative disorders 126
Antiparkinson Prodrugs 125
Sintesi di trans-2-ammino-1-fenil-5-fluoro-6-idrossi (e 6-fluoro-5-idrossi)-2,3-diidro-1H-indeni quali potenziali ligandi per i recettori dopaminergici 124
Ibuprofen and glutathione conjugate as a potential therapeutic agent for treating Alzheimer's disease 122
L-Dopa Prodrugs: An Overview of Trends for Improving Parkinson's Disease Treatment 122
A new lipophilic molecular combination codrug-1 exerts neuroprotective activity in beta amyloid (1-40) infused Alzheimer’s disease rat model 119
Gold nanoparticles as scaffolds for new antiparkinson prodrugs 119
Synthesis and preliminary evaluation of L-dopa/benserazide conjugates as dual acting codrugs 119
Evaluation of 2,3,4,8,13a hexahydro-1H-Benzo[5,6]cyclohepta-6,7-dihydroxy[1,2,3-ef][3]benzazepine derivatives as dopamine receptor ligands 118
Detection of levodopa, dopamine and its metabolites in rat striatum dialysates following peripheral administration of L-DOPA prodrugs by mean of HPLC-EC 114
Biodegradable microspheres loaded with an antiparkinson prodrug: an in vivo pharmacokinetic study 114
Synthesis and Study of L-Dopa-Glutathione Codrugs as New Anti-Parkinson Agents with Free Radical Scavenging Properties. 113
Design, synthesis and preliminary pharmacological evaluation of new imidazolinones as L-DOPA prodrugs. 113
synthesis and Activity of L-Dopa-Thiol antioxidant Co-drugs and New anti-PArkinson Agents with free Radical Scavenging Properties 113
Evaluation of rat striatal L-Dopa and DA concentration after intraperitoneal administration of L- Dopa prodrugs in liposomal formulations 109
Synthesis and preliminary pharmacological evaluation of trans-2-amino-5(6)-chloro-6(5)-hydroxy-1- phenyl-2,3-dihydro-1H-indenes as dopamine receptor ligands 108
New drug delivery strategies for improved Parkinson’s disease therapy 108
Design and synthesis of multifunctional drugs: a strategy to improve the treatment of Parkinson’s disease 108
Ibuprofen and lipoic acid diamide as co-drugs with neuroprotective activity: pharmacological properties and effects in β-amyloid (1-40) infused Alzheimer’s disease rat model. 108
Maleic- and Fumaric-diamides of (O,O-diacetyl)-L-Dopa-methylester as anti-Parkinson prodrugs in liposomal formulation 106
synthesis and biological evaluation as anti-Parkinson agent of an analogue of Glutathione-L-Dopa containing methionine in place of the cysteinil residue 106
Memantine-sulphur containing antioxidant conjugates as potential prodrugs to improve the treatment of Alzheimer’s disease 106
Codrugs Linking l-Dopa and Sulfur-Containing Antioxidants: New Pharmacological Tools against Parkinson’s Disease 105
Synthesis and biological evaluation of a novel pyroglutamil-modified TRH analogue 104
Designing Prodrugs for the Treatment of Parkinson's Disease 104
Transdermal donepezil on the treatment of Alzheimer’s disease 104
Nuovi S-coniugati del glutatione ad attività inibitoria nei confronti delle GST umane 103
Ibuprofen and lipoic acid diamides as potential codrugs with neuroprotective activity 102
NOS-mediated morphological and molecular modifications in rats infused with Aβ (1-40), as a model of Alzheimer’s Disease, in response to a new lipophilic molecular combination codrug-1 102
Preparation and pharmacological characterization of trans-2-amino-5(6)-fluoro-6(5)-hydroxy-1-phenyl-2,3-dihydro-1H-indenes as D2-like dopamine receptor agonists 102
Glycosyl and polyalcoholic prodrugs of lonidamine 100
L-Dopa- and dopamine- (R)-α-lipoic acid conjugates as multifunctional codrugs with antioxidant properties 100
Drug Delivery Strategies for Alzheimer's Disease Treatment 99
Transition state isosteres of the gamma-glutamyl peptide bond hydrolysis: synthesis and characterization of the psi (CH2NH) pseudopeptide analogue of glutathione 99
Dimeric L-dopa derivatives as potential prodrugs. 96
Ibuprofen and lipoic Acid conjugate neuroprotective activity is mediated by ngb/akt intracellular signaling pathway in Alzheimer's disease rat model 96
Potent isozyme-selective inhibition of human glutathione S-transferase A1-1 by a novel glutathione S-conjugate 96
New Flurbiprofen Derivatives: Synthesis, Membrane Affinity and Evaluation of in Vitro Effect on β-Amyloid Levels 94
Synthesis and activity of novel glutathione analogues containing an urethane backbone linkage 92
The Investigation of Cytogenetic and Oxidative Effects of Diffractaic Acid on Human Lymphocyte Cultures 89
Preparation and characterization of poly(lactic-co-glycolic acid) microspheres loaded with a labile antiparkinson prodrug 88
New L-Dopa codrugs as potential antiparkinson agents 88
Dopaminergic system modulation, behavioral changes, and oxidative stress after neonatal administration of pyrethroids 86
Evaluation of cytotoxic, oxidative stress and genotoxic responses of hydroxyapatite nanoparticles on human blood cells 86
Multifuctional L-Dopa Codrugs Containing Antioxidant Molecules 85
Effect of treatment with choline-contining Phospholipids on brain neurontransmitter transporters 83
Ibuprofen-Glutathione Conjugate as Anti-inflammatory and Anti-apoptotic Agent in Rat Brain Infused with β Amyloid (1-40) 82
Protective effects of cyclosativene on H2O 2-induced injury in cultured rat primary cerebral cortex cells 81
Synthesis and biological evaluation of oligopeptides with antioxidant activity useful for treatment of neurodegenerative diseases 80
Effect of choline-containing phospholipids on brain cholinergic transporters in the rat. 80
Modulation of monoaminergic transporters by choline-containing phospholipids in rat brain 80
Haloperidol metabolite II prodrug: Asymmetric synthesis and biological evaluation on rat C6 glioma cells 78
Novel O-palmitoylscleroglucan-coated liposomes as drug carriers: Development, characterization and interation with leuprolide 77
pPKC alpha.mediated effect on in vitro AB production in response to gamma secretase inhibitor LY411575in rat CTXTNA2 astrocytes. 76
Ibuprofen and lipoic acid codrug 1 control Alzheimer's disease progression by down - regulating Protein Kinase C ε – mediated Metalloproteinase 2 and 9 levels in β-amyloid infused Alzheimer's disease rat model 62
Lipid nanocarriers containing a levodopa prodrug with potential antiparkinsonian activity 57
In vivo anti-apoptotic effect of compound 4 in rats infused with Aβ (1-40), as a model of Alzheimer’s disease 56
In vivo anti-apoptotic effect of compound 4 in rats infused with Abeta (1-40), as a model of Alzheimer's disease 55
Novel imidazoline compounds as partial or full agonists of D2-likedopamine receptors inspired by I2-imidazoline binding sites ligand 2-BFI 52
Neuroprotective effects of farnesene against hydrogen peroxide-induced neurotoxicity in vitro 42
Totale 7.127
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Categoria #
all - tutte 29.984
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 29.984
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021283 0 0 0 0 0 83 9 7 20 80 67 17
2021/2022306 5 7 6 44 29 7 7 25 45 17 32 82
2022/20231.096 79 171 62 129 94 229 54 91 122 17 24 24
2023/2024493 35 23 43 12 37 152 125 4 5 5 1 51
2024/20251.202 65 223 183 12 9 115 31 29 73 41 166 255
2025/20261.099 233 99 230 265 229 43 0 0 0 0 0 0
Totale 7.127