IRIS
SOZIO, Piera
 Distribuzione geografica
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Continente #
EU - Europa 1.963
NA - Nord America 1.905
AS - Asia 768
SA - Sud America 5
Continente sconosciuto - Info sul continente non disponibili 4
Totale 4.645
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Nazione #
US - Stati Uniti d'America 1.899
CN - Cina 406
UA - Ucraina 379
IE - Irlanda 316
IT - Italia 315
GB - Regno Unito 283
SE - Svezia 238
TR - Turchia 222
FR - Francia 218
IN - India 123
DE - Germania 103
FI - Finlandia 73
IR - Iran 11
BE - Belgio 9
PL - Polonia 7
ES - Italia 6
RU - Federazione Russa 6
CA - Canada 4
EU - Europa 4
BR - Brasile 3
GR - Grecia 3
HK - Hong Kong 2
HU - Ungheria 2
VN - Vietnam 2
AL - Albania 1
AR - Argentina 1
AT - Austria 1
CH - Svizzera 1
CL - Cile 1
IL - Israele 1
KR - Corea 1
MX - Messico 1
PA - Panama 1
PT - Portogallo 1
RO - Romania 1
Totale 4.645
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Città #
Chandler 415
Jacksonville 413
Dublin 312
Southend 244
Princeton 138
Nanjing 124
Izmir 116
Chieti 98
Dearborn 94
Ashburn 90
Cambridge 69
Wilmington 66
Ann Arbor 59
Altamura 55
Nanchang 44
Beijing 42
Boardman 32
Shenyang 31
Tianjin 24
Washington 24
Kunming 21
Kocaeli 20
New York 19
Woodbridge 18
Jiaxing 16
Grevenbroich 15
Hebei 15
Jinan 13
Leawood 13
Ningbo 13
Zhengzhou 13
Augusta 12
Ardabil 9
Brussels 9
Pescara 9
Teramo 8
Auburn Hills 7
Guangzhou 7
Hangzhou 6
Kraków 6
Los Angeles 6
San Mateo 6
Simi Valley 6
Falls Church 5
Helsinki 5
Lanzhou 5
Norwalk 5
Cepagatti 4
Changsha 4
Hefei 4
Houston 4
Monmouth Junction 4
Naples 4
Orange 4
San Donato Milanese 4
Seattle 4
Sesena Nuevo 4
Silvi 4
Taizhou 4
Tappahannock 4
Changchun 3
Düsseldorf 3
Rovereto 3
Bangalore 2
Dallas 2
Dong Ket 2
Haikou 2
Hong Kong 2
Isernia 2
Lanciano 2
Lucca 2
Milan 2
Mumbai 2
Orpington 2
Parma 2
San Salvo 2
Siena 2
Toronto 2
Ancona 1
Aquila 1
Atatürk 1
Bellante 1
Bucharest 1
Budapest 1
Buffalo 1
Campomarino 1
Castel Di Sangro 1
Chengdu 1
Chicago 1
Chongqing 1
Collecorvino 1
Debrecen 1
Delhi 1
Erzurum 1
Eulmont 1
Fairfield 1
Ferrara 1
Fuzhou 1
Innsbruck 1
Jesi 1
Totale 2.890
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Nome #
Viscoelastic properties of Staphylococcus aureus and Staphylococcus epidermidis mono-microbial biofilms 154
Synthesis of a novel cyclic prodrug of S -allyl-glutathione able to attenuate LPS-induced ROS production through the inhibition of MAPK pathways in U937 cells 113
Synthesis and evaluation of trans-2-amino-5(or 6)-chloro-6(or 5)-hydroxy-1-phenyl-2,3-dihydro-1H-indenes as dopamine receptor ligands 99
Solid lipid nanoparticles loaded with lipoyl-memantine codrug: preparation and characterization 96
(R)-α-Lipoyl-glycyl-L-prolyl-L-glutamyl dimethyl ester codrug as a multifunctional agent with potential neuroprotective activities 93
Characterization of alkanoyl-10-O-minocyclines in micellar dispersions as potential agents for treatment of human neurodegenerative disorders 91
A glutathione derivative with chelating and in vitro neuroprotective activities: synthesis, physicochemical properties, and biological evaluation. 89
Synthesis and preliminary pharmacological evaluation of 2,3,4,8,13a-hexahydro-1H-benzo(5,6)cyclohepta(1,2,3-ef)(3)benzazepine-6,7-diol derivatives as dopamine receptor ligands 85
Sintesi di trans-2-ammino-1-fenil-5-fluoro-6-idrossi (e 6-fluoro-5-idrossi)-2,3-diidro-1H-indeni quali potenziali ligandi per i recettori dopaminergici 85
Synthesis and preliminary evaluation of L-dopa/benserazide conjugates as dual acting codrugs 85
Synthesis and Study of L-Dopa-Glutathione Codrugs as New Anti-Parkinson Agents with Free Radical Scavenging Properties. 84
Gold nanoparticles as scaffolds for new antiparkinson prodrugs 82
Antiparkinson Prodrugs 82
Synthesis and preliminary pharmacological evaluation of trans-2-amino-5(6)-chloro-6(5)-hydroxy-1- phenyl-2,3-dihydro-1H-indenes as dopamine receptor ligands 81
Biodegradable microspheres loaded with an antiparkinson prodrug: an in vivo pharmacokinetic study 81
Potential Antibacterial Activity of Carvacrol-Loaded PLGA Nanoparticles against Microbial Biofilm 81
Design, synthesis and preliminary pharmacological evaluation of new imidazolinones as L-DOPA prodrugs. 80
Ibuprofen and glutathione conjugate as a potential therapeutic agent for treating Alzheimer's disease 80
Ibuprofen and lipoic acid diamide as co-drugs with neuroprotective activity: pharmacological properties and effects in β-amyloid (1-40) infused Alzheimer’s disease rat model. 77
Memantine-sulphur containing antioxidant conjugates as potential prodrugs to improve the treatment of Alzheimer’s disease 77
CNS delivery of L-Dopa by a new Hybrid Glutathione-Methionine peptidomimetic prodrug 76
Transition state isosteres of the gamma-glutamyl peptide bond hydrolysis: synthesis and characterization of the psi (CH2NH) pseudopeptide analogue of glutathione 76
Evaluation of 2,3,4,8,13a hexahydro-1H-Benzo[5,6]cyclohepta-6,7-dihydroxy[1,2,3-ef][3]benzazepine derivatives as dopamine receptor ligands 75
New drug delivery strategies for improved Parkinson’s disease therapy 75
synthesis and biological evaluation as anti-Parkinson agent of an analogue of Glutathione-L-Dopa containing methionine in place of the cysteinil residue 73
Evaluation of rat striatal L-Dopa and DA concentration after intraperitoneal administration of L- Dopa prodrugs in liposomal formulations 72
Codrugs Linking l-Dopa and Sulfur-Containing Antioxidants: New Pharmacological Tools against Parkinson’s Disease 72
synthesis and Activity of L-Dopa-Thiol antioxidant Co-drugs and New anti-PArkinson Agents with free Radical Scavenging Properties 72
Transdermal donepezil on the treatment of Alzheimer’s disease 72
Preparation and pharmacological characterization of trans-2-amino-5(6)-fluoro-6(5)-hydroxy-1-phenyl-2,3-dihydro-1H-indenes as D2-like dopamine receptor agonists 72
Glycosyl and polyalcoholic prodrugs of lonidamine 70
Design and synthesis of multifunctional drugs: a strategy to improve the treatment of Parkinson’s disease 70
L-Dopa Prodrugs: An Overview of Trends for Improving Parkinson's Disease Treatment 70
Nuovi S-coniugati del glutatione ad attività inibitoria nei confronti delle GST umane 69
Detection of levodopa, dopamine and its metabolites in rat striatum dialysates following peripheral administration of L-DOPA prodrugs by mean of HPLC-EC 69
Synthesis and activity of novel glutathione analogues containing an urethane backbone linkage 69
Ibuprofen and lipoic acid diamides as potential codrugs with neuroprotective activity 69
NOS-mediated morphological and molecular modifications in rats infused with Aβ (1-40), as a model of Alzheimer’s Disease, in response to a new lipophilic molecular combination codrug-1 69
Maleic- and Fumaric-diamides of (O,O-diacetyl)-L-Dopa-methylester as anti-Parkinson prodrugs in liposomal formulation 68
Drug Delivery Strategies for Alzheimer's Disease Treatment 68
Potent isozyme-selective inhibition of human glutathione S-transferase A1-1 by a novel glutathione S-conjugate 68
Designing Prodrugs for the Treatment of Parkinson's Disease 67
Synthesis and biological evaluation of a novel pyroglutamil-modified TRH analogue 66
A new lipophilic molecular combination codrug-1 exerts neuroprotective activity in beta amyloid (1-40) infused Alzheimer’s disease rat model 66
Ibuprofen and lipoic Acid conjugate neuroprotective activity is mediated by ngb/akt intracellular signaling pathway in Alzheimer's disease rat model 66
L-Dopa- and dopamine- (R)-α-lipoic acid conjugates as multifunctional codrugs with antioxidant properties 62
Preparation and characterization of poly(lactic-co-glycolic acid) microspheres loaded with a labile antiparkinson prodrug 61
The Investigation of Cytogenetic and Oxidative Effects of Diffractaic Acid on Human Lymphocyte Cultures 60
Dimeric L-dopa derivatives as potential prodrugs. 59
Synthesis and biological evaluation of oligopeptides with antioxidant activity useful for treatment of neurodegenerative diseases 59
New L-Dopa codrugs as potential antiparkinson agents 59
Dopaminergic system modulation, behavioral changes, and oxidative stress after neonatal administration of pyrethroids 58
Effect of choline-containing phospholipids on brain cholinergic transporters in the rat. 57
Modulation of monoaminergic transporters by choline-containing phospholipids in rat brain 57
New Flurbiprofen Derivatives: Synthesis, Membrane Affinity and Evaluation of in Vitro Effect on β-Amyloid Levels 55
Ibuprofen-Glutathione Conjugate as Anti-inflammatory and Anti-apoptotic Agent in Rat Brain Infused with β Amyloid (1-40) 55
Novel O-palmitoylscleroglucan-coated liposomes as drug carriers: Development, characterization and interation with leuprolide 53
Multifuctional L-Dopa Codrugs Containing Antioxidant Molecules 53
Evaluation of cytotoxic, oxidative stress and genotoxic responses of hydroxyapatite nanoparticles on human blood cells 53
Haloperidol metabolite II prodrug: Asymmetric synthesis and biological evaluation on rat C6 glioma cells 52
Protective effects of cyclosativene on H2O 2-induced injury in cultured rat primary cerebral cortex cells 52
Effect of treatment with choline-contining Phospholipids on brain neurontransmitter transporters 51
pPKC alpha.mediated effect on in vitro AB production in response to gamma secretase inhibitor LY411575in rat CTXTNA2 astrocytes. 50
Ibuprofen and lipoic acid codrug 1 control Alzheimer's disease progression by down - regulating Protein Kinase C ε – mediated Metalloproteinase 2 and 9 levels in β-amyloid infused Alzheimer's disease rat model 43
In vivo anti-apoptotic effect of compound 4 in rats infused with Abeta (1-40), as a model of Alzheimer's disease 40
In vivo anti-apoptotic effect of compound 4 in rats infused with Aβ (1-40), as a model of Alzheimer’s disease 37
Novel imidazoline compounds as partial or full agonists of D2-likedopamine receptors inspired by I2-imidazoline binding sites ligand 2-BFI 35
Lipid nanocarriers containing a levodopa prodrug with potential antiparkinsonian activity 34
Neuroprotective effects of farnesene against hydrogen peroxide-induced neurotoxicity in vitro 25
Totale 4.774
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Categoria #
all - tutte 15.668
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 15.668
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019163 0 0 0 0 0 0 0 0 0 0 2 161
2019/2020978 303 73 4 33 71 82 135 94 16 71 87 9
2020/2021483 72 3 71 4 50 83 9 7 20 80 67 17
2021/2022306 5 7 6 44 29 7 7 25 45 17 32 82
2022/20231.096 79 171 62 129 94 229 54 91 122 17 24 24
2023/2024441 35 23 43 12 37 152 125 4 5 5 0 0
Totale 4.774