IRIS
SOZIO, Piera
 Distribuzione geografica
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Continente #
NA - Nord America 3.599
EU - Europa 2.510
AS - Asia 2.249
SA - Sud America 203
Continente sconosciuto - Info sul continente non disponibili 133
AF - Africa 39
Totale 8.733
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Nazione #
US - Stati Uniti d'America 3.522
SG - Singapore 835
CN - Cina 684
UA - Ucraina 386
IT - Italia 372
GB - Regno Unito 335
IE - Irlanda 316
FR - Francia 257
SE - Svezia 243
TR - Turchia 229
RU - Federazione Russa 216
VN - Vietnam 202
DE - Germania 172
BR - Brasile 168
IN - India 162
FI - Finlandia 89
CA - Canada 45
BD - Bangladesh 33
PL - Polonia 26
HK - Hong Kong 24
BE - Belgio 23
ES - Italia 23
CZ - Repubblica Ceca 18
AR - Argentina 17
IQ - Iraq 14
MX - Messico 14
ZA - Sudafrica 14
LT - Lituania 12
IR - Iran 11
KE - Kenya 9
KR - Corea 9
JP - Giappone 8
PK - Pakistan 7
ID - Indonesia 6
CO - Colombia 5
UZ - Uzbekistan 5
EU - Europa 4
IL - Israele 4
SA - Arabia Saudita 4
TN - Tunisia 4
AL - Albania 3
CR - Costa Rica 3
EG - Egitto 3
GR - Grecia 3
PE - Perù 3
PH - Filippine 3
PY - Paraguay 3
BB - Barbados 2
CG - Congo 2
CH - Svizzera 2
CL - Cile 2
DO - Repubblica Dominicana 2
DZ - Algeria 2
EC - Ecuador 2
EE - Estonia 2
ET - Etiopia 2
GT - Guatemala 2
HU - Ungheria 2
JO - Giordania 2
MA - Marocco 2
NL - Olanda 2
RO - Romania 2
VE - Venezuela 2
AM - Armenia 1
AT - Austria 1
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
BG - Bulgaria 1
BH - Bahrain 1
BO - Bolivia 1
DK - Danimarca 1
GA - Gabon 1
GD - Grenada 1
GE - Georgia 1
HN - Honduras 1
HT - Haiti 1
JM - Giamaica 1
MY - Malesia 1
NI - Nicaragua 1
NO - Norvegia 1
NP - Nepal 1
PA - Panama 1
PR - Porto Rico 1
PS - Palestinian Territory 1
PT - Portogallo 1
SV - El Salvador 1
TT - Trinidad e Tobago 1
Totale 8.604
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Città #
Singapore 655
Chandler 415
Jacksonville 413
San Jose 380
Dublin 312
Ashburn 245
Southend 244
Beijing 152
Princeton 138
Council Bluffs 135
Dallas 135
Nanjing 124
Izmir 116
Chieti 101
Dearborn 94
Santa Clara 86
Los Angeles 75
Ho Chi Minh City 70
Cambridge 69
Wilmington 66
Ann Arbor 59
The Dalles 56
Altamura 55
New York 55
Tongling 54
Hanoi 49
Munich 48
Nanchang 44
Boardman 35
Shenyang 31
Buffalo 30
Washington 25
Tianjin 24
Brussels 23
Moscow 23
Kunming 22
Hong Kong 20
Kocaeli 20
Columbus 19
Brno 18
São Paulo 18
Woodbridge 18
Montreal 17
Jiaxing 16
Orem 16
Warsaw 16
Frankfurt am Main 15
Grevenbroich 15
Hebei 15
Phoenix 15
Chennai 14
Ningbo 14
Zhengzhou 14
Brooklyn 13
Houston 13
Jinan 13
Leawood 13
Pescara 13
Augusta 12
Haiphong 12
Hefei 12
Helsinki 12
Redondo Beach 12
Toronto 12
Johannesburg 11
Boston 10
London 10
Ardabil 9
Atlanta 9
Nairobi 9
Turku 9
Bexley 8
Denver 8
Guangzhou 8
Naples 8
Poplar 8
Rome 8
Seoul 8
Teramo 8
Auburn Hills 7
Biên Hòa 7
Mumbai 7
Seattle 7
Tokyo 7
Chicago 6
Da Nang 6
Dhaka 6
Hangzhou 6
Kraków 6
Mexico City 6
Milan 6
Norwalk 6
San Francisco 6
San Mateo 6
Simi Valley 6
West Jordan 6
Bari 5
Falls Church 5
Guarulhos 5
Lanzhou 5
Totale 5.333
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Nome #
Viscoelastic properties of Staphylococcus aureus and Staphylococcus epidermidis mono-microbial biofilms 243
(R)-α-Lipoyl-glycyl-L-prolyl-L-glutamyl dimethyl ester codrug as a multifunctional agent with potential neuroprotective activities 205
A glutathione derivative with chelating and in vitro neuroprotective activities: synthesis, physicochemical properties, and biological evaluation. 175
Solid lipid nanoparticles loaded with lipoyl-memantine codrug: preparation and characterization 172
Synthesis of a novel cyclic prodrug of S -allyl-glutathione able to attenuate LPS-induced ROS production through the inhibition of MAPK pathways in U937 cells 169
Potential Antibacterial Activity of Carvacrol-Loaded PLGA Nanoparticles against Microbial Biofilm 167
Ibuprofen and glutathione conjugate as a potential therapeutic agent for treating Alzheimer's disease 162
CNS delivery of L-Dopa by a new Hybrid Glutathione-Methionine peptidomimetic prodrug 161
Characterization of alkanoyl-10-O-minocyclines in micellar dispersions as potential agents for treatment of human neurodegenerative disorders 153
Ibuprofen and lipoic acid diamide as co-drugs with neuroprotective activity: pharmacological properties and effects in β-amyloid (1-40) infused Alzheimer’s disease rat model. 153
Detection of levodopa, dopamine and its metabolites in rat striatum dialysates following peripheral administration of L-DOPA prodrugs by mean of HPLC-EC 152
Antiparkinson Prodrugs 150
Synthesis and preliminary pharmacological evaluation of 2,3,4,8,13a-hexahydro-1H-benzo(5,6)cyclohepta(1,2,3-ef)(3)benzazepine-6,7-diol derivatives as dopamine receptor ligands 148
Synthesis and evaluation of trans-2-amino-5(or 6)-chloro-6(or 5)-hydroxy-1-phenyl-2,3-dihydro-1H-indenes as dopamine receptor ligands 145
A new lipophilic molecular combination codrug-1 exerts neuroprotective activity in beta amyloid (1-40) infused Alzheimer’s disease rat model 145
Synthesis and preliminary evaluation of L-dopa/benserazide conjugates as dual acting codrugs 145
Evaluation of 2,3,4,8,13a hexahydro-1H-Benzo[5,6]cyclohepta-6,7-dihydroxy[1,2,3-ef][3]benzazepine derivatives as dopamine receptor ligands 143
L-Dopa Prodrugs: An Overview of Trends for Improving Parkinson's Disease Treatment 143
Gold nanoparticles as scaffolds for new antiparkinson prodrugs 143
New drug delivery strategies for improved Parkinson’s disease therapy 140
Design, synthesis and preliminary pharmacological evaluation of new imidazolinones as L-DOPA prodrugs. 140
Sintesi di trans-2-ammino-1-fenil-5-fluoro-6-idrossi (e 6-fluoro-5-idrossi)-2,3-diidro-1H-indeni quali potenziali ligandi per i recettori dopaminergici 138
Codrugs Linking l-Dopa and Sulfur-Containing Antioxidants: New Pharmacological Tools against Parkinson’s Disease 138
Biodegradable microspheres loaded with an antiparkinson prodrug: an in vivo pharmacokinetic study 137
Design and synthesis of multifunctional drugs: a strategy to improve the treatment of Parkinson’s disease 136
Synthesis and Study of L-Dopa-Glutathione Codrugs as New Anti-Parkinson Agents with Free Radical Scavenging Properties. 135
Designing Prodrugs for the Treatment of Parkinson's Disease 135
synthesis and Activity of L-Dopa-Thiol antioxidant Co-drugs and New anti-PArkinson Agents with free Radical Scavenging Properties 134
Evaluation of rat striatal L-Dopa and DA concentration after intraperitoneal administration of L- Dopa prodrugs in liposomal formulations 133
Synthesis and biological evaluation of a novel pyroglutamil-modified TRH analogue 131
Evaluation of cytotoxic, oxidative stress and genotoxic responses of hydroxyapatite nanoparticles on human blood cells 131
L-Dopa- and dopamine- (R)-α-lipoic acid conjugates as multifunctional codrugs with antioxidant properties 130
Synthesis and preliminary pharmacological evaluation of trans-2-amino-5(6)-chloro-6(5)-hydroxy-1- phenyl-2,3-dihydro-1H-indenes as dopamine receptor ligands 127
Memantine-sulphur containing antioxidant conjugates as potential prodrugs to improve the treatment of Alzheimer’s disease 127
Preparation and pharmacological characterization of trans-2-amino-5(6)-fluoro-6(5)-hydroxy-1-phenyl-2,3-dihydro-1H-indenes as D2-like dopamine receptor agonists 126
synthesis and biological evaluation as anti-Parkinson agent of an analogue of Glutathione-L-Dopa containing methionine in place of the cysteinil residue 125
Drug Delivery Strategies for Alzheimer's Disease Treatment 124
Ibuprofen and lipoic acid diamides as potential codrugs with neuroprotective activity 123
Nuovi S-coniugati del glutatione ad attività inibitoria nei confronti delle GST umane 122
Maleic- and Fumaric-diamides of (O,O-diacetyl)-L-Dopa-methylester as anti-Parkinson prodrugs in liposomal formulation 121
NOS-mediated morphological and molecular modifications in rats infused with Aβ (1-40), as a model of Alzheimer’s Disease, in response to a new lipophilic molecular combination codrug-1 121
Transdermal donepezil on the treatment of Alzheimer’s disease 121
Potent isozyme-selective inhibition of human glutathione S-transferase A1-1 by a novel glutathione S-conjugate 121
Glycosyl and polyalcoholic prodrugs of lonidamine 119
Dimeric L-dopa derivatives as potential prodrugs. 117
Transition state isosteres of the gamma-glutamyl peptide bond hydrolysis: synthesis and characterization of the psi (CH2NH) pseudopeptide analogue of glutathione 116
Ibuprofen and lipoic Acid conjugate neuroprotective activity is mediated by ngb/akt intracellular signaling pathway in Alzheimer's disease rat model 115
Dopaminergic system modulation, behavioral changes, and oxidative stress after neonatal administration of pyrethroids 114
New Flurbiprofen Derivatives: Synthesis, Membrane Affinity and Evaluation of in Vitro Effect on β-Amyloid Levels 112
Ibuprofen-Glutathione Conjugate as Anti-inflammatory and Anti-apoptotic Agent in Rat Brain Infused with β Amyloid (1-40) 110
Synthesis and activity of novel glutathione analogues containing an urethane backbone linkage 108
Preparation and characterization of poly(lactic-co-glycolic acid) microspheres loaded with a labile antiparkinson prodrug 108
Multifuctional L-Dopa Codrugs Containing Antioxidant Molecules 106
The Investigation of Cytogenetic and Oxidative Effects of Diffractaic Acid on Human Lymphocyte Cultures 106
New L-Dopa codrugs as potential antiparkinson agents 106
Effect of choline-containing phospholipids on brain cholinergic transporters in the rat. 105
Effect of treatment with choline-contining Phospholipids on brain neurontransmitter transporters 104
Protective effects of cyclosativene on H2O 2-induced injury in cultured rat primary cerebral cortex cells 103
Modulation of monoaminergic transporters by choline-containing phospholipids in rat brain 99
Haloperidol metabolite II prodrug: Asymmetric synthesis and biological evaluation on rat C6 glioma cells 97
Novel O-palmitoylscleroglucan-coated liposomes as drug carriers: Development, characterization and interation with leuprolide 90
Synthesis and biological evaluation of oligopeptides with antioxidant activity useful for treatment of neurodegenerative diseases 90
pPKC alpha.mediated effect on in vitro AB production in response to gamma secretase inhibitor LY411575in rat CTXTNA2 astrocytes. 87
Ibuprofen and lipoic acid codrug 1 control Alzheimer's disease progression by down - regulating Protein Kinase C ε – mediated Metalloproteinase 2 and 9 levels in β-amyloid infused Alzheimer's disease rat model 84
Lipid nanocarriers containing a levodopa prodrug with potential antiparkinsonian activity 73
In vivo anti-apoptotic effect of compound 4 in rats infused with Abeta (1-40), as a model of Alzheimer's disease 72
Novel imidazoline compounds as partial or full agonists of D2-likedopamine receptors inspired by I2-imidazoline binding sites ligand 2-BFI 70
In vivo anti-apoptotic effect of compound 4 in rats infused with Aβ (1-40), as a model of Alzheimer’s disease 69
Neuroprotective effects of farnesene against hydrogen peroxide-induced neurotoxicity in vitro 63
Totale 8.733
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Categoria #
all - tutte 37.006
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 37.006
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022294 0 0 6 44 29 7 7 25 45 17 32 82
2022/20231.096 79 171 62 129 94 229 54 91 122 17 24 24
2023/2024493 35 23 43 12 37 152 125 4 5 5 1 51
2024/20251.202 65 223 183 12 9 115 31 29 73 41 166 255
2025/20262.469 233 99 230 265 229 178 481 144 233 192 142 43
2026/2027236 46 144 46 0 0 0 0 0 0 0 0 0
Totale 8.733