IRIS
SOZIO, Piera
 Distribuzione geografica
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Continente #
NA - Nord America 2.184
EU - Europa 2.114
AS - Asia 1.166
SA - Sud America 65
Continente sconosciuto - Info sul continente non disponibili 4
AF - Africa 2
Totale 5.535
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Nazione #
US - Stati Uniti d'America 2.168
CN - Cina 419
UA - Ucraina 380
SG - Singapore 363
IT - Italia 325
IE - Irlanda 316
GB - Regno Unito 298
SE - Svezia 238
FR - Francia 225
TR - Turchia 223
DE - Germania 126
IN - India 123
FI - Finlandia 82
BR - Brasile 59
RU - Federazione Russa 51
BE - Belgio 23
CZ - Repubblica Ceca 18
CA - Canada 14
HK - Hong Kong 12
IR - Iran 11
ES - Italia 7
PL - Polonia 7
LT - Lituania 6
EU - Europa 4
GR - Grecia 3
PE - Perù 3
AL - Albania 2
BD - Bangladesh 2
HU - Ungheria 2
JP - Giappone 2
VN - Vietnam 2
AM - Armenia 1
AR - Argentina 1
AT - Austria 1
AZ - Azerbaigian 1
CG - Congo 1
CH - Svizzera 1
CL - Cile 1
CO - Colombia 1
EE - Estonia 1
ID - Indonesia 1
IL - Israele 1
IQ - Iraq 1
KR - Corea 1
MX - Messico 1
NP - Nepal 1
PA - Panama 1
PK - Pakistan 1
PT - Portogallo 1
RO - Romania 1
TN - Tunisia 1
UZ - Uzbekistan 1
Totale 5.535
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Città #
Chandler 415
Jacksonville 413
Dublin 312
Singapore 288
Southend 244
Princeton 138
Nanjing 124
Izmir 116
Chieti 98
Dearborn 94
Ashburn 91
Cambridge 69
Wilmington 66
Ann Arbor 59
The Dalles 56
Altamura 55
Santa Clara 54
Nanchang 44
Beijing 42
Boardman 35
Shenyang 31
Tianjin 24
Washington 24
Brussels 23
Kunming 22
Kocaeli 20
New York 19
Brno 18
Woodbridge 18
Jiaxing 16
Grevenbroich 15
Hebei 15
Los Angeles 15
Munich 14
Ningbo 14
Jinan 13
Leawood 13
Zhengzhou 13
Augusta 12
Hong Kong 12
Helsinki 11
Pescara 10
Ardabil 9
Teramo 8
Toronto 8
Auburn Hills 7
Guangzhou 7
Hangzhou 6
Kraków 6
London 6
San Mateo 6
Simi Valley 6
Falls Church 5
Lanzhou 5
Naples 5
Norwalk 5
Ottawa 5
West Jordan 5
Cepagatti 4
Changchun 4
Changsha 4
Frankfurt am Main 4
Hefei 4
Houston 4
Milan 4
Monmouth Junction 4
Moscow 4
Orange 4
San Donato Milanese 4
Seattle 4
Sesena Nuevo 4
Silvi 4
Taizhou 4
Tappahannock 4
Düsseldorf 3
Guarulhos 3
Lima 3
Nuremberg 3
Rovereto 3
Shanghai 3
Turku 3
Bangalore 2
Boydton 2
Cabo Frio 2
Clifton 2
Curitiba 2
Dallas 2
Dong Ket 2
Haikou 2
Isernia 2
Lanciano 2
Lucca 2
Messina 2
Mumbai 2
Orpington 2
Parma 2
Ribeirão Preto 2
Rio de Janeiro 2
Romola 2
San Salvo 2
Totale 3.407
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Nome #
Viscoelastic properties of Staphylococcus aureus and Staphylococcus epidermidis mono-microbial biofilms 178
Synthesis of a novel cyclic prodrug of S -allyl-glutathione able to attenuate LPS-induced ROS production through the inhibition of MAPK pathways in U937 cells 135
A glutathione derivative with chelating and in vitro neuroprotective activities: synthesis, physicochemical properties, and biological evaluation. 120
Solid lipid nanoparticles loaded with lipoyl-memantine codrug: preparation and characterization 117
(R)-α-Lipoyl-glycyl-L-prolyl-L-glutamyl dimethyl ester codrug as a multifunctional agent with potential neuroprotective activities 116
Antiparkinson Prodrugs 112
Synthesis and preliminary pharmacological evaluation of 2,3,4,8,13a-hexahydro-1H-benzo(5,6)cyclohepta(1,2,3-ef)(3)benzazepine-6,7-diol derivatives as dopamine receptor ligands 110
Synthesis and evaluation of trans-2-amino-5(or 6)-chloro-6(or 5)-hydroxy-1-phenyl-2,3-dihydro-1H-indenes as dopamine receptor ligands 107
Characterization of alkanoyl-10-O-minocyclines in micellar dispersions as potential agents for treatment of human neurodegenerative disorders 103
Potential Antibacterial Activity of Carvacrol-Loaded PLGA Nanoparticles against Microbial Biofilm 102
Ibuprofen and glutathione conjugate as a potential therapeutic agent for treating Alzheimer's disease 98
L-Dopa Prodrugs: An Overview of Trends for Improving Parkinson's Disease Treatment 98
Sintesi di trans-2-ammino-1-fenil-5-fluoro-6-idrossi (e 6-fluoro-5-idrossi)-2,3-diidro-1H-indeni quali potenziali ligandi per i recettori dopaminergici 97
CNS delivery of L-Dopa by a new Hybrid Glutathione-Methionine peptidomimetic prodrug 97
Gold nanoparticles as scaffolds for new antiparkinson prodrugs 97
Synthesis and preliminary evaluation of L-dopa/benserazide conjugates as dual acting codrugs 94
Design, synthesis and preliminary pharmacological evaluation of new imidazolinones as L-DOPA prodrugs. 93
Synthesis and Study of L-Dopa-Glutathione Codrugs as New Anti-Parkinson Agents with Free Radical Scavenging Properties. 92
Biodegradable microspheres loaded with an antiparkinson prodrug: an in vivo pharmacokinetic study 92
A new lipophilic molecular combination codrug-1 exerts neuroprotective activity in beta amyloid (1-40) infused Alzheimer’s disease rat model 92
synthesis and Activity of L-Dopa-Thiol antioxidant Co-drugs and New anti-PArkinson Agents with free Radical Scavenging Properties 91
Maleic- and Fumaric-diamides of (O,O-diacetyl)-L-Dopa-methylester as anti-Parkinson prodrugs in liposomal formulation 89
Synthesis and preliminary pharmacological evaluation of trans-2-amino-5(6)-chloro-6(5)-hydroxy-1- phenyl-2,3-dihydro-1H-indenes as dopamine receptor ligands 88
Evaluation of 2,3,4,8,13a hexahydro-1H-Benzo[5,6]cyclohepta-6,7-dihydroxy[1,2,3-ef][3]benzazepine derivatives as dopamine receptor ligands 87
Design and synthesis of multifunctional drugs: a strategy to improve the treatment of Parkinson’s disease 86
Synthesis and biological evaluation of a novel pyroglutamil-modified TRH analogue 85
Detection of levodopa, dopamine and its metabolites in rat striatum dialysates following peripheral administration of L-DOPA prodrugs by mean of HPLC-EC 85
Evaluation of rat striatal L-Dopa and DA concentration after intraperitoneal administration of L- Dopa prodrugs in liposomal formulations 85
synthesis and biological evaluation as anti-Parkinson agent of an analogue of Glutathione-L-Dopa containing methionine in place of the cysteinil residue 85
Ibuprofen and lipoic acid diamide as co-drugs with neuroprotective activity: pharmacological properties and effects in β-amyloid (1-40) infused Alzheimer’s disease rat model. 85
NOS-mediated morphological and molecular modifications in rats infused with Aβ (1-40), as a model of Alzheimer’s Disease, in response to a new lipophilic molecular combination codrug-1 85
Memantine-sulphur containing antioxidant conjugates as potential prodrugs to improve the treatment of Alzheimer’s disease 85
Transition state isosteres of the gamma-glutamyl peptide bond hydrolysis: synthesis and characterization of the psi (CH2NH) pseudopeptide analogue of glutathione 85
Codrugs Linking l-Dopa and Sulfur-Containing Antioxidants: New Pharmacological Tools against Parkinson’s Disease 83
Nuovi S-coniugati del glutatione ad attività inibitoria nei confronti delle GST umane 82
Glycosyl and polyalcoholic prodrugs of lonidamine 82
Designing Prodrugs for the Treatment of Parkinson's Disease 82
Transdermal donepezil on the treatment of Alzheimer’s disease 82
Preparation and pharmacological characterization of trans-2-amino-5(6)-fluoro-6(5)-hydroxy-1-phenyl-2,3-dihydro-1H-indenes as D2-like dopamine receptor agonists 82
New drug delivery strategies for improved Parkinson’s disease therapy 81
Ibuprofen and lipoic acid diamides as potential codrugs with neuroprotective activity 81
Synthesis and activity of novel glutathione analogues containing an urethane backbone linkage 76
L-Dopa- and dopamine- (R)-α-lipoic acid conjugates as multifunctional codrugs with antioxidant properties 74
Drug Delivery Strategies for Alzheimer's Disease Treatment 74
Ibuprofen and lipoic Acid conjugate neuroprotective activity is mediated by ngb/akt intracellular signaling pathway in Alzheimer's disease rat model 74
Potent isozyme-selective inhibition of human glutathione S-transferase A1-1 by a novel glutathione S-conjugate 74
New Flurbiprofen Derivatives: Synthesis, Membrane Affinity and Evaluation of in Vitro Effect on β-Amyloid Levels 73
Dimeric L-dopa derivatives as potential prodrugs. 72
Preparation and characterization of poly(lactic-co-glycolic acid) microspheres loaded with a labile antiparkinson prodrug 71
New L-Dopa codrugs as potential antiparkinson agents 71
Synthesis and biological evaluation of oligopeptides with antioxidant activity useful for treatment of neurodegenerative diseases 68
Effect of treatment with choline-contining Phospholipids on brain neurontransmitter transporters 67
Haloperidol metabolite II prodrug: Asymmetric synthesis and biological evaluation on rat C6 glioma cells 67
The Investigation of Cytogenetic and Oxidative Effects of Diffractaic Acid on Human Lymphocyte Cultures 66
Novel O-palmitoylscleroglucan-coated liposomes as drug carriers: Development, characterization and interation with leuprolide 64
Effect of choline-containing phospholipids on brain cholinergic transporters in the rat. 64
Evaluation of cytotoxic, oxidative stress and genotoxic responses of hydroxyapatite nanoparticles on human blood cells 64
Dopaminergic system modulation, behavioral changes, and oxidative stress after neonatal administration of pyrethroids 63
Ibuprofen-Glutathione Conjugate as Anti-inflammatory and Anti-apoptotic Agent in Rat Brain Infused with β Amyloid (1-40) 63
Modulation of monoaminergic transporters by choline-containing phospholipids in rat brain 61
pPKC alpha.mediated effect on in vitro AB production in response to gamma secretase inhibitor LY411575in rat CTXTNA2 astrocytes. 60
Protective effects of cyclosativene on H2O 2-induced injury in cultured rat primary cerebral cortex cells 60
Multifuctional L-Dopa Codrugs Containing Antioxidant Molecules 58
Ibuprofen and lipoic acid codrug 1 control Alzheimer's disease progression by down - regulating Protein Kinase C ε – mediated Metalloproteinase 2 and 9 levels in β-amyloid infused Alzheimer's disease rat model 50
In vivo anti-apoptotic effect of compound 4 in rats infused with Aβ (1-40), as a model of Alzheimer’s disease 45
In vivo anti-apoptotic effect of compound 4 in rats infused with Abeta (1-40), as a model of Alzheimer's disease 44
Lipid nanocarriers containing a levodopa prodrug with potential antiparkinsonian activity 43
Novel imidazoline compounds as partial or full agonists of D2-likedopamine receptors inspired by I2-imidazoline binding sites ligand 2-BFI 42
Neuroprotective effects of farnesene against hydrogen peroxide-induced neurotoxicity in vitro 30
Totale 5.664
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Categoria #
all - tutte 24.496
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 24.496
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202096 0 0 0 0 0 0 0 0 0 0 87 9
2020/2021483 72 3 71 4 50 83 9 7 20 80 67 17
2021/2022306 5 7 6 44 29 7 7 25 45 17 32 82
2022/20231.096 79 171 62 129 94 229 54 91 122 17 24 24
2023/2024493 35 23 43 12 37 152 125 4 5 5 1 51
2024/2025838 65 223 183 12 9 115 31 29 73 41 57 0
Totale 5.664