IRIS
DI IORIO, Patrizia
 Distribuzione geografica
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Continente #
NA - Nord America 6.441
EU - Europa 4.370
AS - Asia 4.358
SA - Sud America 457
AF - Africa 43
OC - Oceania 7
Continente sconosciuto - Info sul continente non disponibili 4
Totale 15.680
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Nazione #
US - Stati Uniti d'America 6.321
SG - Singapore 1.709
CN - Cina 1.195
IT - Italia 627
UA - Ucraina 619
IE - Irlanda 588
SE - Svezia 526
GB - Regno Unito 465
RU - Federazione Russa 465
TR - Turchia 432
IN - India 407
BR - Brasile 380
VN - Vietnam 304
DE - Germania 302
FR - Francia 295
AT - Austria 199
FI - Finlandia 138
HK - Hong Kong 88
MX - Messico 53
CA - Canada 52
BE - Belgio 30
IQ - Iraq 30
PL - Polonia 28
AR - Argentina 27
BD - Bangladesh 27
JP - Giappone 24
ES - Italia 21
PK - Pakistan 20
KR - Corea 19
NL - Olanda 17
CZ - Repubblica Ceca 15
EC - Ecuador 13
VE - Venezuela 13
ZA - Sudafrica 12
UZ - Uzbekistan 11
CO - Colombia 10
IR - Iran 10
IL - Israele 9
JO - Giordania 8
SA - Arabia Saudita 8
ID - Indonesia 7
MA - Marocco 7
PH - Filippine 7
LT - Lituania 6
NP - Nepal 6
DZ - Algeria 5
OM - Oman 5
RO - Romania 5
RS - Serbia 5
AU - Australia 4
EU - Europa 4
MY - Malesia 4
SY - Repubblica araba siriana 4
TH - Thailandia 4
AZ - Azerbaigian 3
BG - Bulgaria 3
CL - Cile 3
DO - Repubblica Dominicana 3
GR - Grecia 3
JM - Giamaica 3
KE - Kenya 3
PE - Perù 3
PS - Palestinian Territory 3
PY - Paraguay 3
QA - Qatar 3
TN - Tunisia 3
AE - Emirati Arabi Uniti 2
BO - Bolivia 2
CR - Costa Rica 2
DK - Danimarca 2
EG - Egitto 2
ET - Etiopia 2
KG - Kirghizistan 2
KW - Kuwait 2
KZ - Kazakistan 2
NO - Norvegia 2
NZ - Nuova Zelanda 2
PA - Panama 2
PT - Portogallo 2
SN - Senegal 2
AL - Albania 1
BF - Burkina Faso 1
BY - Bielorussia 1
BZ - Belize 1
CG - Congo 1
CH - Svizzera 1
CI - Costa d'Avorio 1
DM - Dominica 1
EE - Estonia 1
GA - Gabon 1
GE - Georgia 1
GY - Guiana 1
HR - Croazia 1
LB - Libano 1
LI - Liechtenstein 1
LS - Lesotho 1
MD - Moldavia 1
MU - Mauritius 1
MZ - Mozambico 1
NI - Nicaragua 1
Totale 15.674
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Città #
Singapore 1.275
Chandler 791
San Jose 683
Jacksonville 657
Dublin 584
Ashburn 487
Southend 298
Beijing 285
Dallas 260
Princeton 259
Izmir 221
Nanjing 205
Dearborn 190
Vienna 188
Los Angeles 162
Chieti 151
Wilmington 150
Santa Clara 141
New York 133
Ann Arbor 130
The Dalles 121
Cambridge 109
Ho Chi Minh City 99
Tongling 83
Hong Kong 77
Hanoi 71
Nanchang 70
Munich 69
Altamura 66
Pescara 66
Boardman 65
Buffalo 62
Council Bluffs 58
Woodbridge 56
São Paulo 53
Moscow 48
Tianjin 44
Rome 41
Hebei 40
Orem 40
Washington 34
Shenyang 33
Hefei 30
Jiaxing 30
Hangzhou 29
Kunming 29
Helsinki 28
Changsha 27
Chennai 27
Kocaeli 27
Seattle 27
Atlanta 25
Falls Church 25
Redondo Beach 24
Brooklyn 23
Brussels 23
Denver 23
Montreal 23
Tokyo 23
Warsaw 23
Houston 22
Norwalk 20
Da Nang 19
Manchester 19
Mexico City 18
Milan 18
San Mateo 18
Augusta 17
Boston 17
Frankfurt am Main 17
Seoul 17
Stockholm 17
Chicago 16
London 16
Jinan 14
Auburn Hills 13
Brno 13
Poplar 13
Dong Ket 12
Ningbo 12
San Francisco 12
Zhengzhou 12
Baghdad 11
Johannesburg 11
Phoenix 11
Redwood City 11
Toronto 11
Turku 11
Amsterdam 10
Ascoli Piceno 9
Orange 9
Querétaro 9
Tashkent 9
Amman 8
Ankara 8
Ardabil 8
Belo Horizonte 8
Biên Hòa 8
Changchun 8
Florianópolis 8
Totale 9.641
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Nome #
RANG & DALE FARMACOLOGIA 228
Activation of P2X(7) receptors stimulates the expression of P2Y(2) receptor mRNA in astrocytes cultured from rat brain. 188
TISSUE DISTRIBUTION AND METABOLISM OF GUANOSINE IN RATS FOLLOWING INTRAPERITONEAL INJECTION. 186
A NEW INVESTIGATIONAL PERSPECTIVE FOR PURINES AGAINST GLIOBLASTOMA INVASIVENESS 174
Cysteinyl-leukotrienes are released from astrocytes and increase astrocyte proliferation and glial fibrillary acidic protein via cys-LT1 receptors and mitogen-activated protein kinase pathway. 172
Altered distribution and function of A2A adenosine receptors in the brain of WAG/Rij rats with genetic absence epilepsy, before and after appearance of the disease. 168
Uncovering the Signaling Pathway behind Extracellular Guanine-Induced Activation of NO System: New Perspectives in Memory-Related Disorders 168
Age-related modifications of distribution, signalling and function of a1 adenosine receptors in the brain of a rat model of absence epilepsy. 167
A1, mGluR2, GABA B receptors CO-modulate purine and EAA S release from rat hippocampal synaptosomes 165
P2X7 receptor activation in rat brain cultured astrocytes increases the biosynthetic release of cysteinyl-leukotrienes. 162
Osteogenic Differentiation of Mesenchymal Stromal Cells: A Comparative Analysis between Human Subcutaneous Adipose Tissue and Dental Pulp 159
Rat astroglial P2Z (P2X7) receptors regulate intracellular calcium and purine release 159
Molecular signalling mediating the protective effect of A1 adenosine and mGlu3 metabotropic glutamate receptor activation against apoptosis by oxygen/glucose deprivation in cultured astrocytes. 158
Involvement of P2X7 Receptors in the Osteogenic Differentiation of Mesenchymal Stromal/Stem Cells Derived from Human Subcutaneous Adipose Tissue 158
The role of wnt signal in glioblastoma development and progression: A possible new pharmacological target for the therapy of this tumor 156
Cultured Astrocyte Proliferation Induced by Extracellular Guanosine Involves Endogenous Adenosine and Is Raised by the Co-Presence of Microglia 155
Does the purinergic system affect extracellular matrix function in the central nervous system? 155
Adenosine-opiods interactions during the development of rat hypothalamus 154
Altered gastrointestinal motility in an animal model of Lesch-Nyhan disease 154
Release of soluble and vesicular purine nucleoside phosphorylase from rat astrocytes and microglia induced by pro-inflammatory stimulation with extracellular ATP via P2X7 receptors 153
Adenosine-norepinephrine interactions on the cyclic cAMP generating-system in human tumoral brain slices. 152
Staurosporine-induced apoptosis in astrocytes is prevented by A1 adenosine receptor activation. 152
Modulation of the TGF-β1-induced epithelial to mesenchymal transition (EMT) mediated by P1 and P2 purine receptors in MDCK cells 151
Regional changes in the metabolite profile after long-term hypoxia-ischemia in brains of young and aged rats: a quantitative proton MRS study 151
Adenosine A1 receptor stimulation enhances osteogenic differentiation of human dental pulp-derived mesenchymal stem cells via WNT signaling. 149
Guanosine protects glial cells against 6-hydroxydopamine toxicity 149
“Region-Specific Effects on Brain Metabolites of Hypoxic and Hyperoxic overlaid on cerebral ischemia in Young and Old Rats : a Quantitative Proton Magnetic Resonance Spectroscopy Study ”. 148
The production of trophic factors of glial origin by guanosine involves mitogen-activated protein Kinase (MAPK) pathway and protects cultured neurons against NMDA excitoxicity. 147
Protective activity of guanosine in an in vitro model of Parkinson's disease. 147
The antiapoptotic effect of guanosine is mediated by the activation of the PI 3-kinase/AKT/PKB pathway in cultured rat astrocytes. 146
A possible link between phospholipase A2-prostaglandin system and purines in the control of glial cultured cell differentiation 146
How purinergic signaling affects bone homeostasis 145
A1 and A2 adenosine receptors involvement in controlling purine and acetylcholine release from rat hippocampal slices 143
Purinoceptor-mediated modulation of purine and neurotransmitter release from nervous tissue. 141
Guanosine inhibits CD40 receptor expression and function induced by cytokines and beta amyloid in mouse microglia cells 141
AIT-082 as a potential neuroprotective and regenerative agent in stroke and central nervous system injury 140
P2Y2 receptor up-regulation induced by guanosine or UTP in rat brain cultured astrocytes. 140
Cytosolic calcium influence on purine release from cultured rat astrocytes. 139
Effects of exogenous ATP and related analogues on the proliferation rate of dissociated primary cultures of rat astrocytes. 138
Glia cells express multiple ATP binding cassette proteins which are involved in ATP release. 138
Purine implication in post-ischaemic functional recovery of isolated rat heart. 138
P2Z-mediated effects on rat astroglial cultures 137
A1-mediated adenosine control and ATP P2Y site involvement in protein kinase C activity and purine release from cultured astrocytes 137
Adenine-Based Purines and Related Metabolizing Enzymes: Evidence for Their Impact on Tumor Extracellular Vesicle Activities 137
Involvement of purine nucleoside phosphorylase in the extracellular breakdownof guanine- and adenine-based nucleosides in rat cultured astrocytes 136
Activation of A1 adenosine or mGlu3 metabotropic glutamate receptors enhances the release of nerve growth factor and S100beta protein from cultured astrocytes 136
Guanosine protects human neuroblastoma cells from oxidative stress and toxicity induced by Amyloid-beta peptide oligomers. 134
Isopentenyladenosine involvement in P2-mediated proliferation of cultured rat astrocytes 133
Guanosine effect on cholesterol efflux and apolipoprotein E expression in astrocytes. 132
AIT-082 is neuroprotective against kainate-induced neuronal injury in rats 132
Potentiation of temozolomide antitumor effect by purine receptor ligands able to restrain the in vitro growth of human glioblastoma stem cells 131
Sodium and calcium dependence of purine release from rat cerebral cortical slices. 130
Purine nucleosides protect injured neurons and stimulate neuronal regeneration by intracellular and membrane receptor-mediated mechanisms. 129
Metabotropic glutamate receptors modulate the stimulation by GTP of rat astrocyte proliferation 126
Influence of Ca2+ channel modulators on [3H]-purine release from rat cultured glial cells. 125
Influence of P2 receptor stimulation on rat astrocyte proliferation 124
Evidence for purine nucleoside phosphorylase (PNP) release from rat C6 glioma cells 124
INVOLVEMENT OF PURINE RECPTORS IN THE GROWTH AND DIFFERENTIATION OF HUMAN GLIOBLASTOMA INITIATING CELLS 122
Modifications of quiescence and functional activity of glial cultured cells by phospholipase A2-prostaglandin system inhibition. 121
Guanine-based purines modulate the effect of L-NAME on learning and memory in rats. 121
Upregulation of Epithelial-To-Mesenchymal Transition Markers and P2X7 Receptors Is Associated to Increased Invasiveness Caused by P2X7 Receptor Stimulation in Human Glioblastoma Stem Cells. 120
Adipose Stromal/Stem Cell-Derived Extracellular Vesicles: Potential Next-Generation Anti-Obesity Agents 119
P2Y1 and cysteinyl-leukotriene receptors mediate purine and cysteinyl-leukotriene co-release in primary cultures of rat microglia. 118
Interaction between metabotropic receptors and purinergic transmission in rat hippocampal slices. 118
The guanine-based purinergic system: The tale of an orphan neuromodulation 118
How purinergic signaling affects bone homeostasis 118
Influence of PLA2-PG system on purine release and cAMP content in dissociated primary glial cultures from rat striatum. 117
Anatomo-functional effects of ionic dilution in the isolated and working heart in the rat 116
Modulation by metabotropic glutamate receptors of GTP effect on rat astrocyte proliferation 115
Adult mesenchymal stem cells: is there a role for purine receptors in their osteogenic differentiation? 115
The hypoxanthine-derivative AIT 082 in neuroprotective in NMDA-induced rat striatal and hippocampal lesions in vivo. 114
Effect of DCG-IV-sensitive metabotropic glutamate receptors on purine and glutamate response from rat hippocampal slices and cultured astrocytes. 111
P2-induced [Ca2+]i modification in rat cultured glial cells. 111
Rat cultured astrocytes release guanine-based purines in basal conditions and after hypoxia/hypoglycemia. 110
Autoregulation of endogenous purine release from rat hippocampal slices 108
In Search of a Role for Extracellular Purine Enzymes in Bone Function 108
Cultures of glial cells release purines under field electrical stimulation: the possible ionic mechanisms. 106
Drug-induced changes of growth kinetics in brain tissue primary cultures. 106
TMB-8 and thapsigargin modulate purine release from dissociated primary cultures of rat brain astrocytes. 106
Alterations in rat prefrontal cortex kynurenic acid levels are involved in the enduring cognitive dysfunctions induced by tetrahydrocannabinol exposure during the adolescence 105
Non-uniform effects mediated by P2Y receptors on the proliferation of cultured astrocytes. 105
Synergic development of pharmacokinetics and bioanalytical methods as support of pharmaceutical research 105
Bidirectional Control between Cholesterol Shuttle and Purine Signal at the Central Nervous System 104
Interaction between A1 adenosine and class II metabotropic glutamate receptors in the regulation of purine and glutamate release from rat hippocampal slices. 104
Calcium-antagonist effect on purine release from dissociated primary glial cultures of rat striatum 104
Guanosine protects against reperfusion injury in rat brains after ischemic stroke. 104
IDENTIFICATION AND FUNCTIONAL ROLE OF A MEMBRANE PURINE NUCLEOSIDE PHOSPHORYLASE (ECTO-PNP). EVIDENCE FOR A POLYMORPHISM IN PNP GENE ASSOCIATED WITH A FAST DECAY OF COGNITIVE ACTIVITY IN PATIENTS WITH ALZHEIMER'S DISEASE. 101
Brain neurotoxic lesion in rats: recogniton and monitoring by means of commercial magnetic 1,5 Tscanner 100
Calcium antagonists modulate 3H-purine release from rat striatum glial cultures via VSCC-dependent and independent mechanisms 100
Farmacologia. Principi di base e applicazioni terapeutiche 100
Evidence for a Basal and electrically evoked release of purines and glutamate from cultured microglial cells of rat brain. 99
The trophic effects of purines and purinergic signaling in pathologic reactions of astrocytes. 99
G-protein coupled receptor 22 transformed cell lines and uses therefor 99
Adenosine and Kynurenic Acid Interactions: Possible Relevance for Schizophrenia Treatment? 98
The calcium-dependent [3H]acetylcholine release from synaptosomes of brown trout (salmo trutta) optic tectum is inhibited by adenosine A1 receptors effects of enucleation on A1 receptor density and cholinergic markers. 96
Involvement of astrocytes in purine-mediated reparative processes in the brain. 95
Specific [3H]-guanosine binding sites in rat membrane astrocytes 94
The Neuroprotective activity of guanosine involves the production of throphic factors and the outflow of purines from astrocytes. 93
Effects of oxygen supply on ischemia-reperfusion damage and endotelial nitric oxide synthase activity. 92
Development of a new HPLC method using fluorescence detection without derivatization for determining purine nucleoside phosphorylase activity in human plasma 92
Totale 13.090
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Categoria #
all - tutte 57.709
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 57.709
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021293 0 0 0 0 0 0 0 0 0 136 77 80
2021/2022735 26 12 17 158 34 20 23 46 75 53 65 206
2022/20232.157 166 248 132 261 247 419 110 158 263 41 55 57
2023/20241.014 67 35 68 29 64 340 218 73 11 32 13 64
2024/20252.501 164 475 436 88 41 88 81 106 230 81 303 408
2025/20264.490 409 229 453 533 484 351 859 347 483 342 0 0
Totale 16.111