IRIS
DI IORIO, Patrizia
 Distribuzione geografica
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Continente #
NA - Nord America 3.631
EU - Europa 3.409
AS - Asia 1.489
SA - Sud America 69
OC - Oceania 5
Continente sconosciuto - Info sul continente non disponibili 4
Totale 8.607
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Nazione #
US - Stati Uniti d'America 3.618
CN - Cina 699
UA - Ucraina 607
IE - Irlanda 586
SE - Svezia 509
IT - Italia 494
TR - Turchia 413
GB - Regno Unito 395
IN - India 344
FR - Francia 266
DE - Germania 205
AT - Austria 177
FI - Finlandia 100
BR - Brasile 63
BE - Belgio 25
RU - Federazione Russa 17
VN - Vietnam 12
ES - Italia 10
CA - Canada 8
IR - Iran 8
IL - Israele 6
EU - Europa 4
AU - Australia 3
MX - Messico 3
PK - Pakistan 3
RO - Romania 3
RS - Serbia 3
BG - Bulgaria 2
CO - Colombia 2
DK - Danimarca 2
GR - Grecia 2
HK - Hong Kong 2
NL - Olanda 2
NZ - Nuova Zelanda 2
AR - Argentina 1
CL - Cile 1
CR - Costa Rica 1
CZ - Repubblica Ceca 1
EC - Ecuador 1
KR - Corea 1
MD - Moldavia 1
NO - Norvegia 1
PA - Panama 1
PL - Polonia 1
PY - Paraguay 1
SG - Singapore 1
Totale 8.607
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Città #
Chandler 791
Jacksonville 657
Dublin 582
Southend 298
Princeton 259
Izmir 220
Nanjing 205
Ashburn 198
Dearborn 190
Vienna 177
Chieti 150
Wilmington 150
Ann Arbor 130
Cambridge 109
Beijing 107
New York 75
Nanchang 70
Altamura 66
Boardman 64
Woodbridge 56
Tianjin 42
Hebei 40
Washington 34
Shenyang 33
Jiaxing 30
Kunming 29
Rome 29
Kocaeli 27
Changsha 26
Falls Church 25
Hangzhou 25
Seattle 23
Brussels 21
Norwalk 20
San Mateo 18
Pescara 17
Augusta 16
Houston 14
Jinan 13
Auburn Hills 12
Dong Ket 12
Ningbo 12
Hefei 11
Redwood City 11
Zhengzhou 10
Orange 9
Ardabil 8
Changchun 8
Lanzhou 8
Bangalore 7
Helsinki 7
Varallo 7
Grevenbroich 6
Guangzhou 6
Cedar Knolls 5
Fairfield 5
Leawood 5
Pune 5
São Paulo 5
Tollo 5
Centrale 4
Florianópolis 4
Gent 4
Guardiagrele 4
La Mancha 4
Lanciano 4
Los Angeles 4
Maringá 4
Milan 4
Mountain View 4
Porto Belo 4
Toronto 4
Belgrade 3
Ceilândia 3
Harringay 3
Jacareí 3
Jodhpur 3
Livorno 3
London 3
Marseille 3
Monmouth Junction 3
Montreal 3
Salerno 3
San Benedetto del Tronto 3
San Salvo 3
San Vito Chietino 3
Simi Valley 3
Spoltore 3
Taizhou 3
Tappahannock 3
Avellino 2
Barceloneta 2
Bari 2
Belém 2
Bezerros 2
Bologna 2
Chicago 2
Cisano Bergamasco 2
Copenhagen 2
Durham 2
Totale 5.322
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Nome #
RANG & DALE FARMACOLOGIA 177
TISSUE DISTRIBUTION AND METABOLISM OF GUANOSINE IN RATS FOLLOWING INTRAPERITONEAL INJECTION. 123
Rat astroglial P2Z (P2X7) receptors regulate intracellular calcium and purine release 115
How purinergic signaling affects bone homeostasis 108
Purine implication in post-ischaemic functional recovery of isolated rat heart. 103
Uncovering the Signaling Pathway behind Extracellular Guanine-Induced Activation of NO System: New Perspectives in Memory-Related Disorders 103
Protective activity of guanosine in an in vitro model of Parkinson's disease. 102
The production of trophic factors of glial origin by guanosine involves mitogen-activated protein Kinase (MAPK) pathway and protects cultured neurons against NMDA excitoxicity. 101
A1, mGluR2, GABA B receptors CO-modulate purine and EAA S release from rat hippocampal synaptosomes 100
The role of wnt signal in glioblastoma development and progression: A possible new pharmacological target for the therapy of this tumor 100
Purinoceptor-mediated modulation of purine and neurotransmitter release from nervous tissue. 99
P2Z-mediated effects on rat astroglial cultures 97
The antiapoptotic effect of guanosine is mediated by the activation of the PI 3-kinase/AKT/PKB pathway in cultured rat astrocytes. 96
Guanosine protects glial cells against 6-hydroxydopamine toxicity 96
Osteogenic Differentiation of Mesenchymal Stromal Cells: A Comparative Analysis between Human Subcutaneous Adipose Tissue and Dental Pulp 96
Staurosporine-induced apoptosis in astrocytes is prevented by A1 adenosine receptor activation. 94
Cytosolic calcium influence on purine release from cultured rat astrocytes. 94
null 91
Release of soluble and vesicular purine nucleoside phosphorylase from rat astrocytes and microglia induced by pro-inflammatory stimulation with extracellular ATP via P2X7 receptors 91
P2X7 receptor activation in rat brain cultured astrocytes increases the biosynthetic release of cysteinyl-leukotrienes. 90
Activation of P2X(7) receptors stimulates the expression of P2Y(2) receptor mRNA in astrocytes cultured from rat brain. 88
P2Y2 receptor up-regulation induced by guanosine or UTP in rat brain cultured astrocytes. 88
Effects of exogenous ATP and related analogues on the proliferation rate of dissociated primary cultures of rat astrocytes. 87
Purine nucleosides protect injured neurons and stimulate neuronal regeneration by intracellular and membrane receptor-mediated mechanisms. 87
Involvement of P2X7 Receptors in the Osteogenic Differentiation of Mesenchymal Stromal/Stem Cells Derived from Human Subcutaneous Adipose Tissue 87
Influence of P2 receptor stimulation on rat astrocyte proliferation 86
A NEW INVESTIGATIONAL PERSPECTIVE FOR PURINES AGAINST GLIOBLASTOMA INVASIVENESS 86
How purinergic signaling affects bone homeostasis 86
“Region-Specific Effects on Brain Metabolites of Hypoxic and Hyperoxic overlaid on cerebral ischemia in Young and Old Rats : a Quantitative Proton Magnetic Resonance Spectroscopy Study ”. 85
Age-related modifications of distribution, signalling and function of a1 adenosine receptors in the brain of a rat model of absence epilepsy. 85
Altered distribution and function of A2A adenosine receptors in the brain of WAG/Rij rats with genetic absence epilepsy, before and after appearance of the disease. 85
Isopentenyladenosine involvement in P2-mediated proliferation of cultured rat astrocytes 84
Molecular signalling mediating the protective effect of A1 adenosine and mGlu3 metabotropic glutamate receptor activation against apoptosis by oxygen/glucose deprivation in cultured astrocytes. 84
Potentiation of temozolomide antitumor effect by purine receptor ligands able to restrain the in vitro growth of human glioblastoma stem cells 84
Does the purinergic system affect extracellular matrix function in the central nervous system? 84
Adenosine-norepinephrine interactions on the cyclic cAMP generating-system in human tumoral brain slices. 83
Guanosine inhibits CD40 receptor expression and function induced by cytokines and beta amyloid in mouse microglia cells 83
Modulation of the TGF-β1-induced epithelial to mesenchymal transition (EMT) mediated by P1 and P2 purine receptors in MDCK cells 82
Cysteinyl-leukotrienes are released from astrocytes and increase astrocyte proliferation and glial fibrillary acidic protein via cys-LT1 receptors and mitogen-activated protein kinase pathway. 81
Adenosine-opiods interactions during the development of rat hypothalamus 81
Sodium and calcium dependence of purine release from rat cerebral cortical slices. 80
Guanosine protects human neuroblastoma cells from oxidative stress and toxicity induced by Amyloid-beta peptide oligomers. 80
A1 and A2 adenosine receptors involvement in controlling purine and acetylcholine release from rat hippocampal slices 80
Regional changes in the metabolite profile after long-term hypoxia-ischemia in brains of young and aged rats: a quantitative proton MRS study 80
Involvement of purine nucleoside phosphorylase in the extracellular breakdownof guanine- and adenine-based nucleosides in rat cultured astrocytes 78
Modifications of quiescence and functional activity of glial cultured cells by phospholipase A2-prostaglandin system inhibition. 76
null 76
Cultured Astrocyte Proliferation Induced by Extracellular Guanosine Involves Endogenous Adenosine and Is Raised by the Co-Presence of Microglia 75
Guanine-based purines modulate the effect of L-NAME on learning and memory in rats. 75
Metabotropic glutamate receptors modulate the stimulation by GTP of rat astrocyte proliferation 74
null 74
Anatomo-functional effects of ionic dilution in the isolated and working heart in the rat 73
Guanosine effect on cholesterol efflux and apolipoprotein E expression in astrocytes. 73
Activation of A1 adenosine or mGlu3 metabotropic glutamate receptors enhances the release of nerve growth factor and S100beta protein from cultured astrocytes 73
Rat cultured astrocytes release guanine-based purines in basal conditions and after hypoxia/hypoglycemia. 72
Evidence for purine nucleoside phosphorylase (PNP) release from rat C6 glioma cells 72
Glia cells express multiple ATP binding cassette proteins which are involved in ATP release. 71
The guanine-based purinergic system: The tale of an orphan neuromodulation 71
P2Y1 and cysteinyl-leukotriene receptors mediate purine and cysteinyl-leukotriene co-release in primary cultures of rat microglia. 70
Influence of Ca2+ channel modulators on [3H]-purine release from rat cultured glial cells. 70
Drug-induced changes of growth kinetics in brain tissue primary cultures. 70
INVOLVEMENT OF PURINE RECPTORS IN THE GROWTH AND DIFFERENTIATION OF HUMAN GLIOBLASTOMA INITIATING CELLS 70
Modulation by metabotropic glutamate receptors of GTP effect on rat astrocyte proliferation 69
A possible link between phospholipase A2-prostaglandin system and purines in the control of glial cultured cell differentiation 69
Effect of DCG-IV-sensitive metabotropic glutamate receptors on purine and glutamate response from rat hippocampal slices and cultured astrocytes. 68
Adenosine A1 receptor stimulation enhances osteogenic differentiation of human dental pulp-derived mesenchymal stem cells via WNT signaling. 68
TMB-8 and thapsigargin modulate purine release from dissociated primary cultures of rat brain astrocytes. 68
Cultures of glial cells release purines under field electrical stimulation: the possible ionic mechanisms. 67
A1-mediated adenosine control and ATP P2Y site involvement in protein kinase C activity and purine release from cultured astrocytes 67
Calcium antagonists modulate 3H-purine release from rat striatum glial cultures via VSCC-dependent and independent mechanisms 67
P2-induced [Ca2+]i modification in rat cultured glial cells. 66
Evidence for a Basal and electrically evoked release of purines and glutamate from cultured microglial cells of rat brain. 65
IDENTIFICATION AND FUNCTIONAL ROLE OF A MEMBRANE PURINE NUCLEOSIDE PHOSPHORYLASE (ECTO-PNP). EVIDENCE FOR A POLYMORPHISM IN PNP GENE ASSOCIATED WITH A FAST DECAY OF COGNITIVE ACTIVITY IN PATIENTS WITH ALZHEIMER'S DISEASE. 65
AIT-082 as a potential neuroprotective and regenerative agent in stroke and central nervous system injury 65
The hypoxanthine-derivative AIT 082 in neuroprotective in NMDA-induced rat striatal and hippocampal lesions in vivo. 65
Brain neurotoxic lesion in rats: recogniton and monitoring by means of commercial magnetic 1,5 Tscanner 64
The calcium-dependent [3H]acetylcholine release from synaptosomes of brown trout (salmo trutta) optic tectum is inhibited by adenosine A1 receptors effects of enucleation on A1 receptor density and cholinergic markers. 64
Synergic development of pharmacokinetics and bioanalytical methods as support of pharmaceutical research 64
Influence of PLA2-PG system on purine release and cAMP content in dissociated primary glial cultures from rat striatum. 63
Calcium-antagonist effect on purine release from dissociated primary glial cultures of rat striatum 62
Autoregulation of endogenous purine release from rat hippocampal slices 62
The Neuroprotective activity of guanosine involves the production of throphic factors and the outflow of purines from astrocytes. 61
Non-uniform effects mediated by P2Y receptors on the proliferation of cultured astrocytes. 61
Altered gastrointestinal motility in an animal model of Lesch-Nyhan disease 61
The trophic effects of purines and purinergic signaling in pathologic reactions of astrocytes. 60
AIT-082 is neuroprotective against kainate-induced neuronal injury in rats 60
Involvement of astrocytes in purine-mediated reparative processes in the brain. 59
Distribution and metabolism of intraperitoneally administered guanosine in rat. 59
Guanosine protects against reperfusion injury in rat brains after ischemic stroke. 59
Effects of oxygen supply on ischemia-reperfusion damage and endotelial nitric oxide synthase activity. 58
Interaction between A1 adenosine and class II metabotropic glutamate receptors in the regulation of purine and glutamate release from rat hippocampal slices. 58
Specific [3H]-guanosine binding sites in rat membrane astrocytes 58
Interaction between metabotropic receptors and purinergic transmission in rat hippocampal slices. 58
Regulatory mechanisms of electrically-evoked endogenous purine release from cultured glial cells. 57
Physiology and pharmacology of natural and synthetic non adenine-based purines in the nervous system 55
Upregulation of Epithelial-To-Mesenchymal Transition Markers and P2X7 Receptors Is Associated to Increased Invasiveness Caused by P2X7 Receptor Stimulation in Human Glioblastoma Stem Cells. 54
Guanosine stimulates neurite outgrowth in PC12 cells via activation of hemeoxygenase and cyclic GMP 53
Mechanisms of apoptosis induced by purine nucleosides in astrocytes. 52
Opposite influence of the metabotropic glutamate receptors subtypes mGlu3 and -5 on astrocyte proliferation in culture. 52
Neuroprotection mediated by glial group-II metabotropic glutamate receptors requires the activation of the MAP kinase and the phosphatidylinositol-3-kinase pathways. 52
Totale 7.740
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Categoria #
all - tutte 26.869
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 26.869
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019349 0 0 0 0 0 0 0 0 0 19 12 318
2019/20201.665 472 110 19 74 117 129 209 146 62 166 150 11
2020/20211.014 155 7 131 15 81 166 20 21 125 136 77 80
2021/2022735 26 12 17 158 34 20 23 46 75 53 65 206
2022/20232.157 166 248 132 261 247 419 110 158 263 41 55 57
2023/2024914 67 35 68 29 64 340 218 73 11 9 0 0
Totale 9.020