DI IORIO, Patrizia
 Distribuzione geografica
Continente #
NA - Nord America 4.102
EU - Europa 3.641
AS - Asia 2.166
SA - Sud America 73
OC - Oceania 6
Continente sconosciuto - Info sul continente non disponibili 4
Totale 9.992
Nazione #
US - Stati Uniti d'America 4.086
CN - Cina 736
SG - Singapore 630
UA - Ucraina 611
IE - Irlanda 586
IT - Italia 531
SE - Svezia 509
TR - Turchia 414
GB - Regno Unito 399
IN - India 349
FR - Francia 277
DE - Germania 243
AT - Austria 179
FI - Finlandia 122
RU - Federazione Russa 110
BR - Brasile 66
BE - Belgio 27
CZ - Repubblica Ceca 15
VN - Vietnam 12
CA - Canada 11
ES - Italia 10
IR - Iran 8
IL - Israele 6
AU - Australia 4
EU - Europa 4
NL - Olanda 4
MX - Messico 3
PK - Pakistan 3
RO - Romania 3
RS - Serbia 3
AE - Emirati Arabi Uniti 2
BG - Bulgaria 2
CO - Colombia 2
DK - Danimarca 2
EC - Ecuador 2
GR - Grecia 2
HK - Hong Kong 2
KR - Corea 2
NZ - Nuova Zelanda 2
AR - Argentina 1
CL - Cile 1
CR - Costa Rica 1
KG - Kirghizistan 1
LI - Liechtenstein 1
LT - Lituania 1
MD - Moldavia 1
NO - Norvegia 1
PA - Panama 1
PL - Polonia 1
PT - Portogallo 1
PY - Paraguay 1
TH - Thailandia 1
Totale 9.992
Città #
Chandler 791
Jacksonville 657
Dublin 582
Singapore 554
Southend 298
Princeton 259
Izmir 220
Nanjing 205
Ashburn 200
Dearborn 190
Vienna 179
Chieti 150
Wilmington 150
Ann Arbor 130
Santa Clara 121
Beijing 111
Cambridge 109
New York 75
Nanchang 70
Altamura 66
Boardman 65
Woodbridge 56
Tianjin 42
Hebei 40
Los Angeles 38
Washington 34
Shenyang 33
Munich 31
Rome 31
Jiaxing 30
Kunming 29
Hangzhou 27
Helsinki 27
Kocaeli 27
Changsha 26
Falls Church 25
Brussels 23
Seattle 23
Norwalk 20
Pescara 20
San Mateo 18
Augusta 16
Houston 14
Jinan 14
Brno 13
Auburn Hills 12
Dong Ket 12
Ningbo 12
Zhengzhou 12
Hefei 11
Redwood City 11
Ascoli Piceno 9
Moscow 9
Orange 9
Ardabil 8
Changchun 8
Frankfurt am Main 8
Guangzhou 8
Lanzhou 8
Milan 8
Bangalore 7
Jodhpur 7
Varallo 7
Grevenbroich 6
Cedar Knolls 5
Fairfield 5
Leawood 5
London 5
Pune 5
São Paulo 5
Tollo 5
Toronto 5
Centrale 4
Chicago 4
Florianópolis 4
Gent 4
Guardiagrele 4
La Mancha 4
Lanciano 4
Maringá 4
Mountain View 4
Porto Belo 4
Belgrade 3
Ceilândia 3
Clifton 3
Copertino 3
Harringay 3
Jacareí 3
Livorno 3
Marseille 3
Monmouth Junction 3
Montreal 3
Paris 3
Salerno 3
San Benedetto del Tronto 3
San Salvo 3
San Vito Chietino 3
Shijiazhuang 3
Simi Valley 3
Spoltore 3
Totale 6.145
Nome #
RANG & DALE FARMACOLOGIA 185
TISSUE DISTRIBUTION AND METABOLISM OF GUANOSINE IN RATS FOLLOWING INTRAPERITONEAL INJECTION. 130
Uncovering the Signaling Pathway behind Extracellular Guanine-Induced Activation of NO System: New Perspectives in Memory-Related Disorders 121
Rat astroglial P2Z (P2X7) receptors regulate intracellular calcium and purine release 120
How purinergic signaling affects bone homeostasis 115
A NEW INVESTIGATIONAL PERSPECTIVE FOR PURINES AGAINST GLIOBLASTOMA INVASIVENESS 114
The production of trophic factors of glial origin by guanosine involves mitogen-activated protein Kinase (MAPK) pathway and protects cultured neurons against NMDA excitoxicity. 113
Purinoceptor-mediated modulation of purine and neurotransmitter release from nervous tissue. 112
Staurosporine-induced apoptosis in astrocytes is prevented by A1 adenosine receptor activation. 110
Osteogenic Differentiation of Mesenchymal Stromal Cells: A Comparative Analysis between Human Subcutaneous Adipose Tissue and Dental Pulp 110
Involvement of P2X7 Receptors in the Osteogenic Differentiation of Mesenchymal Stromal/Stem Cells Derived from Human Subcutaneous Adipose Tissue 110
Release of soluble and vesicular purine nucleoside phosphorylase from rat astrocytes and microglia induced by pro-inflammatory stimulation with extracellular ATP via P2X7 receptors 110
Activation of P2X(7) receptors stimulates the expression of P2Y(2) receptor mRNA in astrocytes cultured from rat brain. 109
The antiapoptotic effect of guanosine is mediated by the activation of the PI 3-kinase/AKT/PKB pathway in cultured rat astrocytes. 109
Altered distribution and function of A2A adenosine receptors in the brain of WAG/Rij rats with genetic absence epilepsy, before and after appearance of the disease. 109
Protective activity of guanosine in an in vitro model of Parkinson's disease. 108
A1, mGluR2, GABA B receptors CO-modulate purine and EAA S release from rat hippocampal synaptosomes 107
P2X7 receptor activation in rat brain cultured astrocytes increases the biosynthetic release of cysteinyl-leukotrienes. 107
The role of wnt signal in glioblastoma development and progression: A possible new pharmacological target for the therapy of this tumor 107
Purine implication in post-ischaemic functional recovery of isolated rat heart. 106
“Region-Specific Effects on Brain Metabolites of Hypoxic and Hyperoxic overlaid on cerebral ischemia in Young and Old Rats : a Quantitative Proton Magnetic Resonance Spectroscopy Study ”. 105
P2Y2 receptor up-regulation induced by guanosine or UTP in rat brain cultured astrocytes. 105
Age-related modifications of distribution, signalling and function of a1 adenosine receptors in the brain of a rat model of absence epilepsy. 103
Modulation of the TGF-β1-induced epithelial to mesenchymal transition (EMT) mediated by P1 and P2 purine receptors in MDCK cells 103
Regional changes in the metabolite profile after long-term hypoxia-ischemia in brains of young and aged rats: a quantitative proton MRS study 103
Isopentenyladenosine involvement in P2-mediated proliferation of cultured rat astrocytes 102
Guanosine protects glial cells against 6-hydroxydopamine toxicity 102
P2Z-mediated effects on rat astroglial cultures 101
Cysteinyl-leukotrienes are released from astrocytes and increase astrocyte proliferation and glial fibrillary acidic protein via cys-LT1 receptors and mitogen-activated protein kinase pathway. 101
Does the purinergic system affect extracellular matrix function in the central nervous system? 101
Cultured Astrocyte Proliferation Induced by Extracellular Guanosine Involves Endogenous Adenosine and Is Raised by the Co-Presence of Microglia 100
Cytosolic calcium influence on purine release from cultured rat astrocytes. 99
Involvement of purine nucleoside phosphorylase in the extracellular breakdownof guanine- and adenine-based nucleosides in rat cultured astrocytes 98
Sodium and calcium dependence of purine release from rat cerebral cortical slices. 96
Guanosine inhibits CD40 receptor expression and function induced by cytokines and beta amyloid in mouse microglia cells 96
A1 and A2 adenosine receptors involvement in controlling purine and acetylcholine release from rat hippocampal slices 96
Adenosine-opiods interactions during the development of rat hypothalamus 96
Adenosine-norepinephrine interactions on the cyclic cAMP generating-system in human tumoral brain slices. 94
How purinergic signaling affects bone homeostasis 94
Influence of P2 receptor stimulation on rat astrocyte proliferation 93
Effects of exogenous ATP and related analogues on the proliferation rate of dissociated primary cultures of rat astrocytes. 93
Purine nucleosides protect injured neurons and stimulate neuronal regeneration by intracellular and membrane receptor-mediated mechanisms. 93
Metabotropic glutamate receptors modulate the stimulation by GTP of rat astrocyte proliferation 92
Potentiation of temozolomide antitumor effect by purine receptor ligands able to restrain the in vitro growth of human glioblastoma stem cells 91
null 91
Modifications of quiescence and functional activity of glial cultured cells by phospholipase A2-prostaglandin system inhibition. 90
Guanosine protects human neuroblastoma cells from oxidative stress and toxicity induced by Amyloid-beta peptide oligomers. 90
Molecular signalling mediating the protective effect of A1 adenosine and mGlu3 metabotropic glutamate receptor activation against apoptosis by oxygen/glucose deprivation in cultured astrocytes. 89
Glia cells express multiple ATP binding cassette proteins which are involved in ATP release. 87
Rat cultured astrocytes release guanine-based purines in basal conditions and after hypoxia/hypoglycemia. 86
Influence of Ca2+ channel modulators on [3H]-purine release from rat cultured glial cells. 86
The guanine-based purinergic system: The tale of an orphan neuromodulation 86
Modulation by metabotropic glutamate receptors of GTP effect on rat astrocyte proliferation 84
Guanosine effect on cholesterol efflux and apolipoprotein E expression in astrocytes. 83
AIT-082 as a potential neuroprotective and regenerative agent in stroke and central nervous system injury 82
Guanine-based purines modulate the effect of L-NAME on learning and memory in rats. 82
Evidence for purine nucleoside phosphorylase (PNP) release from rat C6 glioma cells 81
Altered gastrointestinal motility in an animal model of Lesch-Nyhan disease 81
Anatomo-functional effects of ionic dilution in the isolated and working heart in the rat 80
Activation of A1 adenosine or mGlu3 metabotropic glutamate receptors enhances the release of nerve growth factor and S100beta protein from cultured astrocytes 79
Interaction between metabotropic receptors and purinergic transmission in rat hippocampal slices. 78
Adenosine A1 receptor stimulation enhances osteogenic differentiation of human dental pulp-derived mesenchymal stem cells via WNT signaling. 78
AIT-082 is neuroprotective against kainate-induced neuronal injury in rats 78
P2Y1 and cysteinyl-leukotriene receptors mediate purine and cysteinyl-leukotriene co-release in primary cultures of rat microglia. 77
Effect of DCG-IV-sensitive metabotropic glutamate receptors on purine and glutamate response from rat hippocampal slices and cultured astrocytes. 77
Influence of PLA2-PG system on purine release and cAMP content in dissociated primary glial cultures from rat striatum. 76
INVOLVEMENT OF PURINE RECPTORS IN THE GROWTH AND DIFFERENTIATION OF HUMAN GLIOBLASTOMA INITIATING CELLS 76
null 76
A possible link between phospholipase A2-prostaglandin system and purines in the control of glial cultured cell differentiation 75
Non-uniform effects mediated by P2Y receptors on the proliferation of cultured astrocytes. 74
null 74
Drug-induced changes of growth kinetics in brain tissue primary cultures. 73
Guanosine protects against reperfusion injury in rat brains after ischemic stroke. 73
A1-mediated adenosine control and ATP P2Y site involvement in protein kinase C activity and purine release from cultured astrocytes 72
TMB-8 and thapsigargin modulate purine release from dissociated primary cultures of rat brain astrocytes. 72
Calcium antagonists modulate 3H-purine release from rat striatum glial cultures via VSCC-dependent and independent mechanisms 71
The hypoxanthine-derivative AIT 082 in neuroprotective in NMDA-induced rat striatal and hippocampal lesions in vivo. 71
Cultures of glial cells release purines under field electrical stimulation: the possible ionic mechanisms. 70
Synergic development of pharmacokinetics and bioanalytical methods as support of pharmaceutical research 70
IDENTIFICATION AND FUNCTIONAL ROLE OF A MEMBRANE PURINE NUCLEOSIDE PHOSPHORYLASE (ECTO-PNP). EVIDENCE FOR A POLYMORPHISM IN PNP GENE ASSOCIATED WITH A FAST DECAY OF COGNITIVE ACTIVITY IN PATIENTS WITH ALZHEIMER'S DISEASE. 69
P2-induced [Ca2+]i modification in rat cultured glial cells. 69
Autoregulation of endogenous purine release from rat hippocampal slices 69
Brain neurotoxic lesion in rats: recogniton and monitoring by means of commercial magnetic 1,5 Tscanner 68
Evidence for a Basal and electrically evoked release of purines and glutamate from cultured microglial cells of rat brain. 68
Upregulation of Epithelial-To-Mesenchymal Transition Markers and P2X7 Receptors Is Associated to Increased Invasiveness Caused by P2X7 Receptor Stimulation in Human Glioblastoma Stem Cells. 68
Effects of oxygen supply on ischemia-reperfusion damage and endotelial nitric oxide synthase activity. 66
The calcium-dependent [3H]acetylcholine release from synaptosomes of brown trout (salmo trutta) optic tectum is inhibited by adenosine A1 receptors effects of enucleation on A1 receptor density and cholinergic markers. 66
Calcium-antagonist effect on purine release from dissociated primary glial cultures of rat striatum 66
The Neuroprotective activity of guanosine involves the production of throphic factors and the outflow of purines from astrocytes. 65
The trophic effects of purines and purinergic signaling in pathologic reactions of astrocytes. 65
Interaction between A1 adenosine and class II metabotropic glutamate receptors in the regulation of purine and glutamate release from rat hippocampal slices. 64
Distribution and metabolism of intraperitoneally administered guanosine in rat. 63
Farmaci del doping 63
Involvement of astrocytes in purine-mediated reparative processes in the brain. 62
Specific [3H]-guanosine binding sites in rat membrane astrocytes 62
Monitoring of brain neurotoxic lesions in rats by means of commercial magnetic resonance scanner operating at 1.5 Tesla 62
Adult mesenchymal stem cells: is there a role for purine receptors in their osteogenic differentiation? 62
Physiology and pharmacology of natural and synthetic non adenine-based purines in the nervous system 60
Guanosine stimulates neurite outgrowth in PC12 cells via activation of hemeoxygenase and cyclic GMP 60
Regulatory mechanisms of electrically-evoked endogenous purine release from cultured glial cells. 60
Totale 8.794
Categoria #
all - tutte 38.464
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 38.464


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020744 0 0 0 0 0 0 209 146 62 166 150 11
2020/20211.014 155 7 131 15 81 166 20 21 125 136 77 80
2021/2022735 26 12 17 158 34 20 23 46 75 53 65 206
2022/20232.157 166 248 132 261 247 419 110 158 263 41 55 57
2023/20241.014 67 35 68 29 64 340 218 73 11 32 13 64
2024/20251.293 164 475 436 88 41 88 1 0 0 0 0 0
Totale 10.413