IRIS
D'ORAZI, Gabriella
 Distribuzione geografica
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Continente #
NA - Nord America 5.746
AS - Asia 4.770
EU - Europa 4.244
SA - Sud America 1.071
AF - Africa 64
Continente sconosciuto - Info sul continente non disponibili 7
OC - Oceania 5
Totale 15.907
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Nazione #
US - Stati Uniti d'America 5.660
SG - Singapore 1.775
CN - Cina 1.449
BR - Brasile 916
UA - Ucraina 872
IE - Irlanda 805
TR - Turchia 720
DE - Germania 550
IT - Italia 499
VN - Vietnam 414
SE - Svezia 405
GB - Regno Unito 395
FR - Francia 223
FI - Finlandia 182
RU - Federazione Russa 182
IN - India 161
AR - Argentina 58
CA - Canada 41
EC - Ecuador 38
BD - Bangladesh 37
HK - Hong Kong 37
ID - Indonesia 35
JP - Giappone 28
MX - Messico 27
ZA - Sudafrica 24
AT - Austria 22
BE - Belgio 19
NL - Olanda 18
IQ - Iraq 17
ES - Italia 16
KR - Corea 16
PL - Polonia 16
CO - Colombia 14
PK - Pakistan 13
PY - Paraguay 13
TN - Tunisia 11
IL - Israele 10
MA - Marocco 10
VE - Venezuela 9
CL - Cile 8
LT - Lituania 8
SA - Arabia Saudita 8
EU - Europa 7
UY - Uruguay 7
UZ - Uzbekistan 7
AZ - Azerbaigian 6
GR - Grecia 6
PE - Perù 6
DO - Repubblica Dominicana 5
CZ - Repubblica Ceca 4
IR - Iran 4
JO - Giordania 4
KE - Kenya 4
NG - Nigeria 4
RO - Romania 4
SN - Senegal 4
AE - Emirati Arabi Uniti 3
AU - Australia 3
BH - Bahrain 3
DK - Danimarca 3
KW - Kuwait 3
KZ - Kazakistan 3
NP - Nepal 3
PH - Filippine 3
AL - Albania 2
AO - Angola 2
CH - Svizzera 2
CR - Costa Rica 2
DZ - Algeria 2
EE - Estonia 2
EG - Egitto 2
KG - Kirghizistan 2
NZ - Nuova Zelanda 2
OM - Oman 2
RS - Serbia 2
SV - El Salvador 2
TT - Trinidad e Tobago 2
BB - Barbados 1
BG - Bulgaria 1
BN - Brunei Darussalam 1
BO - Bolivia 1
BY - Bielorussia 1
CU - Cuba 1
GD - Grenada 1
GT - Guatemala 1
HN - Honduras 1
HU - Ungheria 1
LA - Repubblica Popolare Democratica del Laos 1
MD - Moldavia 1
ML - Mali 1
MO - Macao, regione amministrativa speciale della Cina 1
MY - Malesia 1
NI - Nicaragua 1
NO - Norvegia 1
PA - Panama 1
PS - Palestinian Territory 1
PT - Portogallo 1
QA - Qatar 1
SK - Slovacchia (Repubblica Slovacca) 1
SR - Suriname 1
Totale 15.906
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Città #
Singapore 1.284
Jacksonville 1.072
Dublin 799
Chandler 690
Princeton 416
Dallas 369
Izmir 359
Nanjing 320
Southend 308
Beijing 307
Ashburn 305
Wilmington 216
Cambridge 171
Santa Clara 156
Los Angeles 148
Tongling 141
Ann Arbor 135
Ho Chi Minh City 135
Altamura 122
Nanchang 119
Dearborn 113
The Dalles 96
Buffalo 91
Chieti 91
Grevenbroich 90
Woodbridge 80
São Paulo 76
Hanoi 71
Dong Ket 68
Redondo Beach 64
Grafing 57
New York 57
Rome 53
Kunming 52
Shenyang 48
Hebei 42
Boardman 41
Tianjin 39
Nuremberg 36
Hong Kong 34
Washington 34
Jiaxing 33
Norwalk 33
Hefei 31
Changsha 26
Rio de Janeiro 23
Tokyo 23
Chicago 21
Moscow 20
Brussels 19
Hangzhou 19
Jinan 19
Seattle 19
Brooklyn 18
Belo Horizonte 17
Brasília 17
Guayaquil 16
Houston 16
Pescara 16
Haiphong 15
Stockholm 14
Changchun 13
Council Bluffs 13
Falls Church 13
Guarulhos 13
Lappeenranta 13
London 13
Montreal 13
Salvador 13
San Francisco 13
Campinas 12
Chennai 12
Phoenix 12
Seoul 12
Denver 11
Lanzhou 11
Porto Alegre 11
Warsaw 11
Zhengzhou 11
Atlanta 10
Curitiba 10
Dhaka 10
Fortaleza 10
Johannesburg 10
Da Nang 9
Frankfurt am Main 9
Guangzhou 9
Jakarta 9
Manaus 9
Milan 9
Ninh Bình 9
Quito 9
Ribeirão Preto 9
Vienna 9
Ankara 8
Asunción 8
Bologna 8
Ningbo 8
Orange 8
Poplar 8
Totale 9.728
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Nome #
Carvacrol reduces adipogenic differentiation by modulating autophagy and ChREBP expression 154
Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategies 131
A fluorescent curcumin-based Zn(II)-complex reactivates mutant (R175H and R273H) p53 in cancer cells 125
Xenotransplantion in immunodepressed nude mice of human solid tumors and acute leukemias directly from patients or in vitro cell lines. 122
Wild-type p53-mediated down-modulation of IL-15 and IL-15 receptors in human rhabdomyosarcoma cells. 118
HIPK2 neutralizes MDM2 inhibition rescuing p53 transcriptional activity and apoptotic function 115
Apigenin, by activating p53 and inhibiting STAT3, modulates the balance between pro-apoptotic and pro-survival pathways to induce PEL cell death 115
Zn(II)-curc targets p53 in thyroid cancer cells 115
Hyperglycemia triggers HIPK2 protein degradation 114
Activation of p53/p21waf1 pathway is associated with senescence during v-Ha-ras transformation of immortal C2C12 myoblasts. 113
Azurin modulates the association of Mdm2 with p53: SPR evidence from interaction of the full-length proteins. 112
Homeodomain-interacting protein kinase 2 phosphorylates p53 at Ser46 and mediates apoptosis 111
HIPK2 role in the tumor-host interaction: Impact on fibroblasts transdifferentiation CAF-like 110
Analysis of MMP-2 and MMP-9 activity in prostate fluids, tissue homogenates and primary cell culture from patients with prostate cancer or benign prostate disease 109
Overexpression of HIPK2 circumvents the blockade of apoptosis in chemoresistant ovarian cancer cells. 108
Exogenous wt-p53 protein is active in transformed cells but not in their non-transformed counterparts: implications for cancer gene therapy without tumor targeting. 107
Aspetti differenziativi in una coltura di cellule dell'epitelio intestinale e sintesi di matrice extracellulare 105
Sep corticali e midollari nel ratto dopo trauma spinale 105
Zinc supplementation is required for the cytotoxic and immunogenic effects of chemotherapy in chemoresistant p53-functionally deficient cells 105
Counteracting MDM2-induced HIPK2 downregulation restores HIPK2/p53 apoptotic signaling in cancer cells. 104
p53 reactivation: The link to zinc 104
Activation of p53-dependent apoptosis in HIPK2 depleted tumor cells: an approach of combination therapy with drug, zinc, and deacetylase inhibitors 103
Reactivation of mutant p53 by capsaicin, the major constituent of peppers 103
Aspetti ultastrutturali di lingua e paradenzio di ratti alimentati con dieta aproteica 101
Follicle-stimulating hormone increases the expression of tissue inhibitors of metalloproteinases TIMP-1 and TIMP-2 and induces TIMP-1 AP-1 site binding complex(es) in prepubertal rat Sertoli cells 100
Zinc supplementation augments in vivo antitumor effect of chemotherapy by restoring p53 function. 100
Aspetti differenziativi in una coltura di cellule dell'epitelio intestinale e sintesi di matrice extracellulare 100
Homeodomain-interacting protein kinase-2 activity and p53 phosphorylation are critical events for cisplatin-mediated apoptosis. 100
HIPK2 knock-down compromises tumor cell efficiency to repair damaged DNA. 98
The beneficial effect of Zinc(II) on low-dose chemotherapeutic sensitivity involves p53 activation in wild-type p53-carrying colorectal cancer cells 98
Zinc supplementation to chemotherapy of tumor cells restores p53 and HIPK2 activities, chemosensitivity and reduces tumor growth 97
Analysis of type V collagen as a component of breast carcinoma desmoplastic stroma 97
Autophagy manipulation as a strategy for efficient anticancer therapies: Possible consequences 97
Ciclo cellulare e radiazioni 96
Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis 95
Zinc supplementation counteracts cobalt-induced inhibition of homeodomain-interacting protein kinase-2 (HIPK2) and restores tumor chemosensitivity and p53 apoptotic function 95
P53-Dependent PUMA to DRAM antagonistic interplay as a key molecular switch in cell-fate decision in normal/high glucose conditions 95
Zinc supplementation to cancer cells counteracts hypoxia-induced inhibition of HIPK2, suppresses HIF-1alpha activity and restores p53Ser46-dependent drug response 94
HIPK2 regulates beta-catenin level and transcriptional potential 94
Etiologia delle lesioni papillari vescicali: nota preliminare 93
Functional role of the HIPK2/p53 interaction in differentiation and development 93
Wt-p53 has suppressor activity only in fully transformed cells 93
Studio della matrice extracellulare come marker tumorale 92
Cisti odontogene dei mascellari: aspetti ultrastrutturali dello stroma 92
HSP70 inhibition by 2-phenylethynesulfonamide induces lysosomal cathepsin D release and immunogenic cell death in primary effusion lymphoma 92
Abrogation of p53 activity by HIPK2 down-regulation 91
Zinco come adiuvante nelle chemioterapie per la riattivazione del pathway oncosoppressorio HIPK2/p53 91
Ruolo della fibronectina (FN) nell'interazione NK-cellula bersaglio 90
Studio ultrastrutturale ed immunoelettromicroscopico dello stroma desmoplastico nel carcinoma della mammella. 90
HIPK2 contributes to PCAF-mediated p53 acetylation and selective transactivation of p21Waf1 after nonapoptotic DNA damage. 90
Homeodomain-interacting protein kinase-2 restrains cytosolic phospholipase A2-dependent prostaglandin E2 generation in human colorectal cancer cells. 90
Combination therapy strategies in HIPK2 knockdown tumor cells require Sirt1 inhibitor to activate p53 apoptotic transcription 90
Restoring wtp53 activity in HIPK2 depleted MCF7 cells by modulating metallothionein and zinc. 90
p53 can inhibit cell proliferation through caspase-mediated cleavage of ERK2/MAPK. 89
HIPK2-induced p53Ser46 phosphorylation activates the KILLER/DR5-mediated caspase-8 extrinsic apoptotic pathway. 89
Blockade of HIPK2 apoptotic function is involved in chemoresistance to cisplatin in ovarian cancer cells 89
Mutant P53, stabilized by its interplay with HSP90, activates a positive feed-back loop between NRF2 and P62 that induces chemo-resistance to apigenin in pancreatic cancer cells 89
Laminin production by Natural Killer cells 88
The 72-kDa and the 92-kDa gelatinases, but not their inhibitors TIMP-1 and TIMP-2, are expressed in early psoriatic lesions. 88
Sintesi di laminina da parte delle cellule NK e dei linfociti T di ratto 88
Ultrastructurale evidence of the mechanism responsible for Interleukin-4 activated rejection of a spontaneous murine adenocarcinoma. 88
Zinc downregulates HIF-1α and inhibits its activity in tumor cells in vitro and in vivo. 87
Hypoxia-inducible factor -1 (HIF-1) antagonizes p53-mediated apoptosis 87
A novel Zn(II)-compound reactivates mutant p53 protein in cancer cells: molecular mechanisms and therapeutical implications 87
Mutant p53 proteins alter cancer cell secretome and tumour microenvironment: Involvement in cancer invasion and metastasis 87
A ruthenium(II)-curcumin compound modulates NRF2 expression balancing the cancer cell death/survival outcome according to p53 status 87
Considerazioni clinico-prognostiche sui tumori carcinoidi dell’ileo 86
Updates on HIPK2: a resourceful oncosuppressor for clearing cancer 86
Histone deacetylase inhibitors VPA and TSA induce apoptosis and autophagy in pancreatic cancer cells 86
Cytotoxic Drugs Activate KSHV Lytic Cycle in Latently Infected PEL Cells by Inducing a Moderate ROS Increase Controlled by HSF1, NRF2 and p62/SQSTM1 86
Tp53-gene transfer induces hypersensitivity to low doses of X-rays in glioblastoma cells: a strategy to convert a radio-resistant phenotype into a radiosensitive one. 85
Exogenous wt-p53 expression is not detrimental for normal cells: implications for tumor gene therapy 85
Exogenous wt-p53 is stable and transcriptionally active in transformed cells but not in their non-transformed counterparts: implications for cancer gene therapy without tumor targeting 85
Targeting hypoxia in cancer cells by restoring homeodomain interacting protein-kinase 2 and p53 activity and suppressing HIF-1alpha. 84
P53 can inhibit cell proliferation through caspase-mediated cleavage of ERK/MAPK 84
Expression and synthesis of fibronectin and laminin by an intestinal epithelial cell line 83
P53 activity in normal and tumor cells 83
Aspetti ultrastrutturali ed immunochimici della componente vasale del timo in condizioni normali e patologiche 83
Clearing mutant p53 with natural compounds: implication for anticancer therapeutical approaches 83
Homeodomain interacting protein kinase 2: a target for Alzheimer's beta amyloid leading to misfolded p53 and inappropriate cell survival. 82
Ultrastructural study of interleukin-4 induced rejection of a spontaneous murine adenocarcinoma 82
Targeting mutant p53 in cancer: the latest insights 82
Ewing's sarcoma lines synthesize laminin and fibronectin. 81
Ultrastructure of human breast carcinoma from a pleural effusion 81
Misfolded p53 conformation in Alzheimer cells depends on deregulated HIPK2 that can be counteracted by zinc 81
TP53 enhances the radiation-induced hypersensitivity in human glioblastoma cell lines with different endogenous p53 status 81
Unfolded p53 in the pathogenesis of Alzheimer's disease: is HIPK2 the link? 80
Modulation of laminin synthesis in human neuroblastoma cells during retinoic acid induced differentiation. 80
Rat natural killer cells synthesize fibronectin: possible involvement in the cytotoxic function. 80
N(6)-Methyldeoxyadenosine, a nucleoside commonly found in prokaryotes, induces C2C12 myogenic differentiation. 80
Tumor cell response to cisplatin requires HIPK2 and p53 phosphorylation at ser46 80
Riattivazione di p53 mediante zinco: prospettive nella terapia dei glioblastomi 80
Interplay between endoplasmic reticulum (ER) stress and autophagy induces mutant p53H273 degradation 80
Zinc antagonizes HIF-1/VEGF signaling in vitro and in vivo 79
Metformin triggers apoptosis in PEL cells and alters bortezomib-induced Unfolded Protein Response increasing its cytotoxicity and inhibiting KSHV lytic cycle activation 79
Chloroquine supplementation increases the cytotoxic effect of curcumin against Her2/neu overexpressing breast cancer cells in vitro and in vivo in nude mice while counteracts it in immune competent mice 79
Reduced chemotherapeutic sensitivity in high glucose condition: implication of antioxidant response 79
ZnCl2 sustains the adriamycin-induced cell death inhibited by high glucose 79
HIPK2 downregulates vimentin and inhibits breast cancer cell invasion 78
Il trasferimento genico di p53 induce iper-sensibilita‚ alle basse dosi di raggi X in cellule di glioblastoma: una nuova strategia per convertire il fenotipo radio-resistente in radio-sensibile 78
Totale 9.365
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Categoria #
all - tutte 72.250
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 72.250
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021598 0 0 0 0 0 223 18 22 44 164 26 101
2021/2022828 6 6 4 48 80 68 22 70 68 20 111 325
2022/20232.223 275 353 178 216 130 475 179 126 186 25 50 30
2023/2024977 62 36 70 33 52 280 264 52 6 38 14 70
2024/20252.947 289 517 331 65 37 106 44 154 395 132 243 634
2025/20263.353 438 251 905 1.265 440 54 0 0 0 0 0 0
Totale 16.854