IRIS
D'ORAZI, Gabriella
 Distribuzione geografica
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Continente #
NA - Nord America 4.354
EU - Europa 3.930
AS - Asia 2.546
Continente sconosciuto - Info sul continente non disponibili 7
OC - Oceania 5
SA - Sud America 4
AF - Africa 3
Totale 10.849
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Nazione #
US - Stati Uniti d'America 4.341
CN - Cina 986
UA - Ucraina 862
IE - Irlanda 803
TR - Turchia 698
SG - Singapore 632
DE - Germania 493
IT - Italia 461
SE - Svezia 391
GB - Regno Unito 351
FR - Francia 182
FI - Finlandia 173
RU - Federazione Russa 161
IN - India 129
VN - Vietnam 68
BE - Belgio 19
CA - Canada 9
HK - Hong Kong 9
IL - Israele 8
EU - Europa 7
GR - Grecia 6
JP - Giappone 6
NL - Olanda 6
CZ - Repubblica Ceca 4
KR - Corea 4
AT - Austria 3
AU - Australia 3
BR - Brasile 3
DK - Danimarca 3
ES - Italia 3
IR - Iran 3
RO - Romania 3
MX - Messico 2
NG - Nigeria 2
NZ - Nuova Zelanda 2
PH - Filippine 2
AL - Albania 1
BG - Bulgaria 1
CU - Cuba 1
DZ - Algeria 1
MD - Moldavia 1
MO - Macao, regione amministrativa speciale della Cina 1
NO - Norvegia 1
PA - Panama 1
PL - Polonia 1
SK - Slovacchia (Repubblica Slovacca) 1
VE - Venezuela 1
Totale 10.849
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Città #
Jacksonville 1.070
Dublin 797
Chandler 689
Singapore 537
Princeton 416
Izmir 359
Nanjing 320
Southend 308
Wilmington 216
Cambridge 171
Ashburn 169
Beijing 162
Santa Clara 139
Ann Arbor 135
Altamura 122
Nanchang 119
Dearborn 113
Chieti 91
Grevenbroich 90
Woodbridge 80
Dong Ket 68
Grafing 57
Kunming 52
Rome 47
Shenyang 44
Hebei 42
Boardman 41
Tianjin 38
Los Angeles 35
Jiaxing 33
Norwalk 33
Washington 31
Changsha 25
Brussels 19
Hangzhou 19
Jinan 18
Moscow 18
Seattle 15
Changchun 13
Falls Church 13
Lanzhou 11
Zhengzhou 11
Pescara 10
Guangzhou 9
Houston 9
New York 8
Ningbo 8
Orange 8
Lappeenranta 7
Milan 7
Romola 7
Tappahannock 7
Andover 6
Bologna 6
Fairfield 6
Florence 6
Hefei 6
Helsinki 6
Hong Kong 6
L'aquila 6
Simi Valley 6
Hanover 5
Taizhou 5
Auburn Hills 4
Edinburgh 4
Fuzhou 4
Menlo Park 4
San Mateo 4
Avezzano 3
Chicago 3
Guidonia 3
Isfahan 3
Latina 3
Macerata 3
Munich 3
Shenzhen 3
Taiyuan 3
Tokyo 3
Toronto 3
Atlanta 2
Buffalo 2
Cebu City 2
Chongqing 2
Cormeilles-en-Parisis 2
Crotone 2
Cwmbran 2
Gothenburg 2
Jinhua 2
Lagos 2
London 2
Madrid 2
Mexico City 2
Montréal 2
Mountain View 2
Olomouc 2
Ortona 2
Ottawa 2
Palermo 2
Parma 2
Pieve a Nievole 2
Totale 7.025
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Nome #
Carvacrol reduces adipogenic differentiation by modulating autophagy and ChREBP expression 118
Xenotransplantion in immunodepressed nude mice of human solid tumors and acute leukemias directly from patients or in vitro cell lines. 102
Zn(II)-curc targets p53 in thyroid cancer cells 96
Exogenous wt-p53 protein is active in transformed cells but not in their non-transformed counterparts: implications for cancer gene therapy without tumor targeting. 95
A fluorescent curcumin-based Zn(II)-complex reactivates mutant (R175H and R273H) p53 in cancer cells 93
Homeodomain-interacting protein kinase 2 phosphorylates p53 at Ser46 and mediates apoptosis 92
Wild-type p53-mediated down-modulation of IL-15 and IL-15 receptors in human rhabdomyosarcoma cells. 91
Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategies 91
Sep corticali e midollari nel ratto dopo trauma spinale 84
Zinc supplementation to chemotherapy of tumor cells restores p53 and HIPK2 activities, chemosensitivity and reduces tumor growth 84
Homeodomain-interacting protein kinase-2 activity and p53 phosphorylation are critical events for cisplatin-mediated apoptosis. 84
Follicle-stimulating hormone increases the expression of tissue inhibitors of metalloproteinases TIMP-1 and TIMP-2 and induces TIMP-1 AP-1 site binding complex(es) in prepubertal rat Sertoli cells 83
Hyperglycemia triggers HIPK2 protein degradation 83
p53 reactivation: The link to zinc 81
Aspetti differenziativi in una coltura di cellule dell'epitelio intestinale e sintesi di matrice extracellulare 80
Apigenin, by activating p53 and inhibiting STAT3, modulates the balance between pro-apoptotic and pro-survival pathways to induce PEL cell death 78
HIPK2 role in the tumor-host interaction: Impact on fibroblasts transdifferentiation CAF-like 78
Etiologia delle lesioni papillari vescicali: nota preliminare 77
HIPK2 neutralizes MDM2 inhibition rescuing p53 transcriptional activity and apoptotic function 77
Azurin modulates the association of Mdm2 with p53: SPR evidence from interaction of the full-length proteins. 77
Aspetti differenziativi in una coltura di cellule dell'epitelio intestinale e sintesi di matrice extracellulare 77
The beneficial effect of Zinc(II) on low-dose chemotherapeutic sensitivity involves p53 activation in wild-type p53-carrying colorectal cancer cells 77
Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis 76
HIPK2 regulates beta-catenin level and transcriptional potential 76
Reactivation of mutant p53 by capsaicin, the major constituent of peppers 76
Ultrastructurale evidence of the mechanism responsible for Interleukin-4 activated rejection of a spontaneous murine adenocarcinoma. 76
Activation of p53/p21waf1 pathway is associated with senescence during v-Ha-ras transformation of immortal C2C12 myoblasts. 75
Cisti odontogene dei mascellari: aspetti ultrastrutturali dello stroma 74
p53 can inhibit cell proliferation through caspase-mediated cleavage of ERK2/MAPK. 74
Homeodomain-interacting protein kinase-2 restrains cytosolic phospholipase A2-dependent prostaglandin E2 generation in human colorectal cancer cells. 74
Hypoxia-inducible factor -1 (HIF-1) antagonizes p53-mediated apoptosis 74
null 74
Ruolo della fibronectina (FN) nell'interazione NK-cellula bersaglio 73
Zinc downregulates HIF-1α and inhibits its activity in tumor cells in vitro and in vivo. 73
Activation of p53-dependent apoptosis in HIPK2 depleted tumor cells: an approach of combination therapy with drug, zinc, and deacetylase inhibitors 73
Blockade of HIPK2 apoptotic function is involved in chemoresistance to cisplatin in ovarian cancer cells 73
Laminin production by Natural Killer cells 72
Functional role of the HIPK2/p53 interaction in differentiation and development 72
Mutant P53, stabilized by its interplay with HSP90, activates a positive feed-back loop between NRF2 and P62 that induces chemo-resistance to apigenin in pancreatic cancer cells 72
Studio della matrice extracellulare come marker tumorale 71
Aspetti ultastrutturali di lingua e paradenzio di ratti alimentati con dieta aproteica 71
The 72-kDa and the 92-kDa gelatinases, but not their inhibitors TIMP-1 and TIMP-2, are expressed in early psoriatic lesions. 71
Restoring wtp53 activity in HIPK2 depleted MCF7 cells by modulating metallothionein and zinc. 71
Zinco come adiuvante nelle chemioterapie per la riattivazione del pathway oncosoppressorio HIPK2/p53 70
Cytotoxic Drugs Activate KSHV Lytic Cycle in Latently Infected PEL Cells by Inducing a Moderate ROS Increase Controlled by HSF1, NRF2 and p62/SQSTM1 70
Considerazioni clinico-prognostiche sui tumori carcinoidi dell’ileo 69
HIPK2 knock-down compromises tumor cell efficiency to repair damaged DNA. 69
Mutant p53 proteins alter cancer cell secretome and tumour microenvironment: Involvement in cancer invasion and metastasis 69
Analysis of MMP-2 and MMP-9 activity in prostate fluids, tissue homogenates and primary cell culture from patients with prostate cancer or benign prostate disease 68
Histone deacetylase inhibitors VPA and TSA induce apoptosis and autophagy in pancreatic cancer cells 68
Targeting mutant p53 in cancer: the latest insights 68
Studio ultrastrutturale ed immunoelettromicroscopico dello stroma desmoplastico nel carcinoma della mammella. 67
MDM2 transcriptional and posttranscriptional regulation by the HIPK2/p53 complex: a novel pathway for regulating p53 apoptotic function 67
Zinc supplementation counteracts cobalt-induced inhibition of homeodomain-interacting protein kinase-2 (HIPK2) and restores tumor chemosensitivity and p53 apoptotic function 67
ZnCl2 sustains the adriamycin-induced cell death inhibited by high glucose 67
Overexpression of HIPK2 circumvents the blockade of apoptosis in chemoresistant ovarian cancer cells. 67
Modulation of laminin synthesis in human neuroblastoma cells during retinoic acid induced differentiation. 66
Expression and synthesis of fibronectin and laminin by an intestinal epithelial cell line 66
Zinc supplementation augments in vivo antitumor effect of chemotherapy by restoring p53 function. 65
Combination therapy strategies in HIPK2 knockdown tumor cells require Sirt1 inhibitor to activate p53 apoptotic transcription 65
Abrogation of p53 activity by HIPK2 down-regulation 65
P53-Dependent PUMA to DRAM antagonistic interplay as a key molecular switch in cell-fate decision in normal/high glucose conditions 65
Nobel committee honors tumor immunologists 65
Counteracting MDM2-induced HIPK2 downregulation restores HIPK2/p53 apoptotic signaling in cancer cells. 64
Tumor cell response to cisplatin requires HIPK2 and p53 phosphorylation at ser46 64
Ciclo cellulare e radiazioni 64
Exogenous wt-p53 expression is not detrimental for normal cells: implications for tumor gene therapy 64
Unfolded p53 in the pathogenesis of Alzheimer's disease: is HIPK2 the link? 63
Autophagy manipulation as a strategy for efficient anticancer therapies: Possible consequences 63
Clearing mutant p53 with natural compounds: implication for anticancer therapeutical approaches 63
Restoring drug-induced apoptosis in hypoxia-treated tumor cells by modulating HIPK2/p53 and HIF-1alpha pathways 62
Expression and synthesis of fibronectin (FN) by rat NK cells: Possible involvement in the NK-target interaction 62
Analysis of type V collagen as a component of breast carcinoma desmoplastic stroma 62
HSP70 inhibition by 2-phenylethynesulfonamide induces lysosomal cathepsin D release and immunogenic cell death in primary effusion lymphoma 62
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). 62
Metformin triggers apoptosis in PEL cells and alters bortezomib-induced Unfolded Protein Response increasing its cytotoxicity and inhibiting KSHV lytic cycle activation 62
Rat natural killer cells synthesize fibronectin: possible involvement in the cytotoxic function. 61
The homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser46 and mediates apoptosis 61
Updates on HIPK2: a resourceful oncosuppressor for clearing cancer 61
Chloroquine supplementation increases the cytotoxic effect of curcumin against Her2/neu overexpressing breast cancer cells in vitro and in vivo in nude mice while counteracts it in immune competent mice 61
Zinc supplementation to cancer cells counteracts hypoxia-induced inhibition of HIPK2, suppresses HIF-1alpha activity and restores p53Ser46-dependent drug response 60
Establishment and characterization of a human continuous cell line from a IVs neuroblastoma 60
HIF-1α antagonizes p53-mediated apoptosis by triggering HIPK2 degradation. 60
Type IV collagenase(s) and TIMPs modulate endothelial cell morphogenesis in vitro 59
Localization of type IV and V collagens in the stroma of human amnion. 59
Ewing's sarcoma lines synthesize laminin and fibronectin. 59
N(6)-Methyldeoxyadenosine, a nucleoside commonly found in prokaryotes, induces C2C12 myogenic differentiation. 59
Homeodomain interacting protein kinase 2: a target for Alzheimer's beta amyloid leading to misfolded p53 and inappropriate cell survival. 59
Sintesi di laminina da parte delle cellule NK e dei linfociti T di ratto 59
Immunohystochemical distribution of type IV gelatinase A and type V collagen in ductal invasive carcinoma 59
HIPK2 inhibits both MDM2 gene and protein by, respectively, p53-dependent and independent regulations. 59
Wt-p53 interferes with the v-Ha-ras pathway by inactivating ERK2/MAPK 58
Wt-p53 has suppressor activity only in fully transformed cells 58
Riattivazione di p53 mediante zinco: prospettive nella terapia dei glioblastomi 58
Ultrastructural study of interleukin-4 induced rejection of a spontaneous murine adenocarcinoma 58
HIPK2 contributes to PCAF-mediated p53 acetylation and selective transactivation of p21Waf1 after nonapoptotic DNA damage. 57
Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways 57
Increase of BCNU sensitivity by wt-p53 gene therapy in glioblastoma lines depends on the administration schedule. 56
Laminin expression by rat lymphoid cells. 56
Tp53-gene transfer induces hypersensitivity to low doses of X-rays in glioblastoma cells: a strategy to convert a radio-resistant phenotype into a radiosensitive one. 56
Totale 7.009
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Categoria #
all - tutte 48.287
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 48.287
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.586 0 0 0 0 171 96 263 321 114 338 245 38
2020/20211.080 181 22 211 12 56 223 18 22 44 164 26 101
2021/2022828 6 6 4 48 80 68 22 70 68 20 111 325
2022/20232.224 275 353 178 216 130 475 179 126 187 25 50 30
2023/2024977 62 36 70 33 52 280 264 52 6 38 14 70
2024/20251.233 289 517 331 65 31 0 0 0 0 0 0 0
Totale 11.788