IRIS
PATRIGNANI, Paola
 Distribuzione geografica
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Continente #
NA - Nord America 11.448
EU - Europa 8.893
AS - Asia 7.800
SA - Sud America 1.048
AF - Africa 95
Continente sconosciuto - Info sul continente non disponibili 25
OC - Oceania 13
Totale 29.322
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Nazione #
US - Stati Uniti d'America 11.258
CN - Cina 2.827
SG - Singapore 2.791
UA - Ucraina 1.824
IE - Irlanda 1.432
GB - Regno Unito 1.294
TR - Turchia 1.240
IT - Italia 937
SE - Svezia 902
BR - Brasile 894
FR - Francia 815
DE - Germania 621
FI - Finlandia 373
RU - Federazione Russa 324
VN - Vietnam 263
IN - India 258
PL - Polonia 146
CA - Canada 99
HK - Hong Kong 76
AR - Argentina 68
MX - Messico 66
KR - Corea 54
CZ - Repubblica Ceca 47
BD - Bangladesh 46
BE - Belgio 45
JP - Giappone 45
ZA - Sudafrica 43
ES - Italia 38
SA - Arabia Saudita 31
IQ - Iraq 25
NL - Olanda 24
EC - Ecuador 23
ID - Indonesia 23
EU - Europa 21
AT - Austria 19
CO - Colombia 19
IL - Israele 18
LT - Lituania 17
IR - Iran 15
AE - Emirati Arabi Uniti 14
MA - Marocco 14
EG - Egitto 12
PK - Pakistan 12
AU - Australia 11
UZ - Uzbekistan 11
VE - Venezuela 11
PY - Paraguay 10
PE - Perù 8
CL - Cile 7
DZ - Algeria 7
AZ - Azerbaigian 6
GR - Grecia 6
HN - Honduras 6
BY - Bielorussia 5
JO - Giordania 5
LY - Libia 5
OM - Oman 5
RO - Romania 5
AL - Albania 4
JM - Giamaica 4
KE - Kenya 4
MY - Malesia 4
PS - Palestinian Territory 4
UY - Uruguay 4
AM - Armenia 3
BB - Barbados 3
BO - Bolivia 3
KW - Kuwait 3
PA - Panama 3
PH - Filippine 3
TH - Thailandia 3
TN - Tunisia 3
TT - Trinidad e Tobago 3
XK - ???statistics.table.value.countryCode.XK??? 3
BA - Bosnia-Erzegovina 2
BH - Bahrain 2
BN - Brunei Darussalam 2
CH - Svizzera 2
DO - Repubblica Dominicana 2
HR - Croazia 2
KZ - Kazakistan 2
LK - Sri Lanka 2
MN - Mongolia 2
NG - Nigeria 2
NO - Norvegia 2
NP - Nepal 2
NZ - Nuova Zelanda 2
PT - Portogallo 2
TW - Taiwan 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BG - Bulgaria 1
CG - Congo 1
CR - Costa Rica 1
DM - Dominica 1
EE - Estonia 1
ET - Etiopia 1
GA - Gabon 1
GT - Guatemala 1
GY - Guiana 1
LB - Libano 1
Totale 29.316
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Città #
Jacksonville 1.967
Singapore 1.958
Chandler 1.728
Dublin 1.422
Southend 1.002
Princeton 705
Dallas 695
Izmir 638
Beijing 584
Dearborn 568
Ashburn 504
Nanjing 494
Cambridge 324
Wilmington 311
Los Angeles 302
Tongling 270
Nanchang 200
The Dalles 186
Santa Clara 181
Altamura 171
Buffalo 162
Boardman 157
Chieti 135
Shenyang 132
Woodbridge 120
Ann Arbor 114
New York 112
Hebei 93
Kraków 93
Munich 92
Ho Chi Minh City 90
São Paulo 86
Tianjin 84
Grevenbroich 83
Jiaxing 75
Council Bluffs 74
Hong Kong 73
Kunming 72
Changsha 68
Hanoi 61
Redondo Beach 61
Hangzhou 52
Hefei 52
Norwalk 51
Seoul 51
Warsaw 50
Jinan 44
Brussels 41
Brooklyn 40
Pescara 40
Orange 39
Chicago 38
Montreal 38
Washington 38
Houston 37
Brno 36
Helsinki 36
Denver 35
Tokyo 35
Rome 34
Kocaeli 31
Johannesburg 30
Toronto 29
Chennai 28
Guangzhou 28
Ningbo 28
Phoenix 28
Lanzhou 27
Seattle 26
Shanghai 26
Zhengzhou 26
Atlanta 25
Orem 25
Augusta 24
Boston 24
Nuremberg 24
Poplar 24
San Mateo 24
London 23
Rio de Janeiro 23
Mexico City 22
Riyadh 22
Auburn Hills 21
Belo Horizonte 21
Stockholm 21
Camerino 19
Moscow 19
San Francisco 19
Ankara 18
Leawood 18
Charlotte 17
Dong Ket 17
Mumbai 17
Spoltore 17
Taizhou 17
Düsseldorf 16
Frankfurt am Main 14
Milan 14
Romola 14
Amsterdam 13
Totale 17.913
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Nome #
“DERIVATI ISOSSAZOLICI E LORO IMPIEGO COME INIBITORI DELLA CICLOOSSIGENASI” 215
Low-dose aspirin acetylates cyclooxygenase-1 in human colorectal mucosa: implications for the chemoprevention of colorectal cancer. 158
Response to "Pharmacodynamic Interaction Between Aspirin and Ibuprofen: A Plausible Mechanism of Aspirin Resistance" 143
Reappraisal of the clinical pharmacology of low-dose aspirin by comparing novel direct and traditional indirect biomarkers of drug action 139
Reduced variability to aspirin antiplatelet effect by the coadministration of statins in high-risk patients for cardiovascular disease. 139
Antithrombotic Agents and Cancer 137
The biochemical selectivity of novel COX-2 inhibitors in whole blood assays of COX-isozyme activity. 131
Aspirin prevents colorectal cancer metastasis in mice by splitting the crosstalk between platelets and tumor cells. 130
Nonsteroidal anti-inflammatory drugs and cardiovascular safety - translating pharmacological data into clinical readouts. 130
Effects of AF3442 [N-(9-ethyl-9H-carbazol-3-yl)-2-(trifluoromethyl)benzamide], a novel inhibitor of human microsomal prostaglandin E synthase-1, on prostanoid biosynthesis in human monocytes in vitro. 128
ROLE OF DOSE POTENCY IN THE PREDICTION OF RISK OF MYOCARDIAL INFARCTION ASSOCIATED WITH NONSTEROIDAL ANTI-INFLAMMATORY DRUGS IN THE GENERAL POPULATION. 127
Dysregulated post-transcriptional control of COX-2 gene expression in gestational diabetic endothelial cells 127
Platelet-specific deletion of cyclooxygenase-1 ameliorates dextran sulfate sodium-induced colitis in mice. 127
Effects of estrogen on endothelial prostanoid production and cyclooxygenase-2 and heme oxygenase-1 expression. 126
Heterogeneity in the suppression of platelet cyclooxygenase-1 activity by aspirin in coronary heart disease 124
Low-dose naproxen interferes with the antiplatelet effects of aspirin in healthy subjects: recommendations to minimize the functional consequences 123
Grand challenges in pharmacotherapy of inflammation for the first decades of the 21st century. 123
miR-574-5p as RNA decoy for CUGBP1 stimulates human lung tumor growth by mPGES-1 induction. 122
Thromboxane biosynthesis and pulmonary function in cystic fibrosis 121
LA CASCATA DELL'ACIDO ARACHIDONICO 121
Platelet-Derived Microparticles From Obese Individuals: Characterization of Number, Size, Proteomics, and Crosstalk With Cancer and Endothelial Cells. 121
Platelets as crucial partners for tumor metastasis: from mechanistic aspects to pharmacological targeting 119
Rare SNP rs12731181 in the miR-590-3p Target Site of the Prostaglandin F2α Receptor Gene Confers Risk for Essential Hypertension in the Han Chinese Population. 119
Biochemical and pharmacological characterization of the cyclooxygenase activity of human blood prostaglandin endoperoxide synthases 118
New insights into COX-2 biology and inhibition. 118
Differential contribution of cycloooxygenase-isozymes to the generation of prostacyclin and prostaglandin E2 by endothelial cells in response to steady laminar shear stress 117
Dysregulation of gene expression in human fetal endothelial cells from gestational diabetes in response to TGF-β1 117
A comparison of low-dose aspirin and dazoxiben as selective inhibitors of thromboxane A2 production in man. 115
ALTERED RENAL AND PLATELET ARACHIDONIC ACID METABOLISM IN CIRRHOSIS. 115
Novel insights into the regulation of cyclooxygenase-2 expression by platelet-cancer cell cross-talk. 115
Aspirin after acute myocardial infarction: a systematic approach to compare the hemostatic effects of three different doses. 114
Clinical pharmacology of etoricoxib: a novel selective COX2 inhibitor. 114
Measurement of 8-iso-prostaglandin F2alpha in biological fluids as a measure of lipid peroxidation 114
PROSTAGLANDIN E2-MEDIATED ACTIVATION OF PHOSPHATIDYLINOSITOL 3-OH KINASE DIFFERENTIALLY AFFECTS IL-10 AND IL-1β PRODUCTION IN BLOOD CELLS. 112
Synthesis, pharmacological characterization, and docking analysis of a novel family of diarylisoxazoles as highly selective cyclooxygenase-1 (COX-1) inhibitors. 112
Celecoxib, ibuprofen, and the antiplatelet effect of aspirin in patients with osteoarthritis and ischemic heart disease 111
Clinical pharmacology of selective COX-2 inhibitors. 111
Effetto del propranololo e del suo metabolita attivo 4-OH propranololo sui prostanoidi COX-2 derivati e sull’emossigenasi-1 (OH-1) in cellule HUVEC. 111
Oxidative stress and platelet activation in essential hyperytension 109
[ITALIAN CONSENSUS ON EULAR 2003 RECOMMENDATIONS FOR THE TREATMENT OF KNEE OSTEOARTHRITIS.] 109
Reduced thromboxane biosynthesis in carriers of toll-like receptor 4 polymorphisms in vivo. 109
ISOXAZOLE DERIVATIVES AND THEIR USE AS CYCLOOXYGENASE INHIBITORS 109
Aspirin and Cancer 109
THE SELECTIVITY OF NOVEL COX-2 INHIBITORS IN HUMAN WHOLE BLOOD ASSAYS OF COX-ISOZYME ACTIVITY. 108
Platelet activation in patients with colorectal cancer. 108
Induction of prostacyclin by steady laminar shear stress suppresses Tumor Necrosis Factor-alfa biosyntesis via Heme Oxygenase-1 in human endothelial cells. 108
A class of pyrrole derivatives endowed with analgesic/anti-inflammatory activity. 108
Therapeutic targeting of dysregulated cellular communication. 108
Modulation of prostaglandin h synthase-2 (pghs-2) expression in human monocytes by glucocorticoids. 107
LOW-DOSE NAPROXEN INTERFERES WITH THE ANTIPLATELET EFFECT OF LOW-DOSE ASPIRIN IN HEALTHY SUBJECTS. 107
T-type channel blocking properties and antiabsence activity of two imidazo[1,2-b]pyridazine derivatives structurally related to indomethacin. 107
Pharmacodynamic interaction of naproxen with low-dose aspirin in healthy subjects 107
Aspirin after acute myocardial infarction: a systematic approach to compare the hemostatic effects of three different doses. 106
Mechanisms of the antitumoural effects of aspirin in the gastrointestinal tract. 106
AMPLIFICATION LOOPS: THROMBOXANE GENERATION. 105
Curbing tumorigenesis and malignant progression through the pharmacological control of the wound healing process. 105
INIBITORI SELETTIVI DI COX-2: LE NUOVE MOLECOLE 104
Advances in NSAID development: Evolution of diclofenac products using pharmaceutical technology 104
Mechanistic and pharmacological issues of aspirin as an anticancer agent 104
A SELECTIVE THROMBOXANE-SYNTHASE INHIBITOR, ON PLATELET AND RENAL PROSTAGLANDIN ENDOPEROXIDE METABOLISM 103
Increased thromboxane production by monocyte prostaglandin endoperoxide synthase-2 in patients with acute myocardial infarction (pubbl. su Suppl. Circulation) 102
A double-blind randomized study of the anti-platelet effects of low-dose ASA and placebo in patients after myocardial infarction 102
RECOVERY OF THROMBOXANE BIOSYNTHESIS BY ASPIRIN-TREATED PLATELETS IN VITRO: A NOVEL MECHANISM OF ASPIRIN RESISTANCE. 102
Cardiovascular effects of valdecoxib: transducing human pharmacology results into clinical read-outs. 102
Pharmacological inhibition of platelet-tumor cell cross-talk prevents platelet-induced overexpression of cyclooxygenase-2 in HT29 human colon carcinoma cells. 102
Incomplete suppression of platelet COX-1 activity associated with aspirin-resistant thromboxane biosynthesis in acute coronary syndromes 102
NCX 4040, a Nitric Oxide-Donating Aspirin, Exerts Anti-Inflammatory Effects through Inhibition of I{kappa}B-{alpha} Degradation in Human Monocytes. 102
Aspirin, platelet inhibition and cancer prevention. 102
The future of traditional nonsteroidal antiinflammatory drugs and cyclooxygenase-2 inhibitors in the treatment of inflammation and pain. 101
Dose-dependent inhibition of platelet cyclooxygenase-1 and monocyte cyclooxygenase-2 by meloxicam in healthy subjects 101
Gut microbiota, host gene expression, and aging. 101
Clinical pharmacology of cyclooxygenase inhibition and pharmacodynamic interaction with aspirin by floctafenine in Thai healthy subjects. 101
Risk management profile of etoricoxib: An example of personalized medicine 101
Usefulness of enzimatic intermediate markers-example of cox-2 inhibition 100
CLINICAL PHARMACOLOGY OF CYCLOOXYGENASE INHIBITION BY NAPROXEN AND LOW-DOSE ASPIRIN. 100
OXIDATIVE STRESS AND PLATELET ACTIVATION IN HUMAN ESSENTIAL HYPERTENSION. 100
CYCLOOXYGENASE-2-DERIVED PROSTACYCLIN RESTRAIN PLATELET THROMBOXANE BIOSYNTHESIS IN TOLL-LIKE RECEPTOR 4 POLYMORPHISM 100
Clinical pharmacology of novel selective COX-2 inhibitors. 100
Cyclooxygenase inhibitors: From pharmacology to clinical read-outs 100
Role of dose potency in the prediction of risk of myocardial infarction associated with nonsteroidal anti-inflammatory drugs in the general population. 100
ANTIINFLAMMATORY COMPOUNDS L-745,337 AND NS-398 ARE SELECTIVE INHIBITORS OF PROSTAGLANDIN ENDOPEROXIDE SYNTHASE-2 IN HUMAN BLOOD MONOCYTES 99
De novo synthesis of cyclooxygenase-1 counteracts the suppression of platelet thromboxane biosynthesis by aspirin. 99
Increased oxidative stress and platelet activation in patients with hypertension and renovascular disease. 99
In vitro morphine metabolism by rat microglia. 99
Novel insights into the vasoprotective role of heme oxygenase-1. 99
Platelets and extracellular vesicles in cancer: diagnostic and therapeutic implications 99
Differential suppression of thromboxane biosynthesis by indobufen and aspirin in patients with unstable angina. 98
Altered release of cytochrome p450 metabolites of arachidonic acid in renovascular disease. 98
Effects of celecoxib on prostanoid biosynthesis and circulating angiogenesis proteins in familial adenomatous polyposis. 98
Novel analgesic/anti-inflammatory agents: 1,5-diarylpyrrole nitrooxyalkyl ethers and related compounds as cyclooxygenase-2 inhibiting nitric oxide donors. 98
Determinants of platelet activation in human essential hypertension. 98
Effects of Acetaminophen on Constitutive and Inducible Prostanoid Biosynthesis in Human Blood Cells in vitro 97
Effects of nabumetone on prostanoid biosynthesis in humans. 97
Repeated exposure to codeine alters morphine glucuronidation by affecting UGT gene expression in the rat. 97
Dose- Dependent inhibition of platelet cyclooxygenase-1 and monocyte cyclooxygenase-2 by meloxicam in healthy subjects. 96
INDUCTION OF PROSTACYCLIN BY STEADY LAMINAR SHEAR STRESS SUPPRESSES TUMOR NECROSIS FACTOR-ALPHA BIOSYNTHESIS VIA HEME OXYGENASE-1 IN HUMAN ENDOTHELIAL CELLS. 96
Clinical pharmacology of etoricoxib. 96
NSAIDs and cardiovascular disease: transducing human pharmacology results into clinical read-outs in the general population. 96
Mechanistic aspects of COX-2 expression in colorectal neoplasia. 96
NSAIDs and cardiovascular disease. 96
Totale 11.086
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Categoria #
all - tutte 125.341
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 125.341
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.260 0 0 0 0 0 427 48 42 170 349 85 139
2021/20221.264 12 16 38 202 122 9 25 103 123 25 192 397
2022/20234.632 374 433 179 589 495 970 291 409 626 55 90 121
2023/20241.827 163 100 131 53 100 456 496 36 7 35 17 233
2024/20254.671 368 638 539 105 104 152 89 383 481 213 545 1.054
2025/20265.170 955 557 1.246 1.366 841 205 0 0 0 0 0 0
Totale 30.208