IRIS
PATRIGNANI, Paola
 Distribuzione geografica
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Continente #
NA - Nord America 8.599
EU - Europa 8.381
AS - Asia 4.397
Continente sconosciuto - Info sul continente non disponibili 22
AF - Africa 14
OC - Oceania 11
SA - Sud America 10
Totale 21.434
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Nazione #
US - Stati Uniti d'America 8.572
CN - Cina 1.905
UA - Ucraina 1.813
IE - Irlanda 1.431
TR - Turchia 1.210
GB - Regno Unito 1.204
SG - Singapore 1.016
SE - Svezia 881
IT - Italia 839
FR - Francia 780
DE - Germania 546
FI - Finlandia 356
RU - Federazione Russa 303
IN - India 184
PL - Polonia 95
CZ - Repubblica Ceca 47
BE - Belgio 45
CA - Canada 21
EU - Europa 21
VN - Vietnam 17
IL - Israele 14
IR - Iran 13
NL - Olanda 12
JP - Giappone 10
AU - Australia 9
BR - Brasile 8
AE - Emirati Arabi Uniti 6
EG - Egitto 6
GR - Grecia 6
MX - Messico 5
RO - Romania 5
ZA - Sudafrica 5
AT - Austria 4
BY - Bielorussia 4
HK - Hong Kong 4
IQ - Iraq 4
KR - Corea 3
LT - Lituania 3
NO - Norvegia 2
NZ - Nuova Zelanda 2
PH - Filippine 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BD - Bangladesh 1
CG - Congo 1
CH - Svizzera 1
CL - Cile 1
CO - Colombia 1
EE - Estonia 1
ES - Italia 1
GT - Guatemala 1
HR - Croazia 1
ID - Indonesia 1
KZ - Kazakistan 1
MA - Marocco 1
MN - Mongolia 1
MY - Malesia 1
OM - Oman 1
PK - Pakistan 1
SC - Seychelles 1
SI - Slovenia 1
TH - Thailandia 1
TW - Taiwan 1
Totale 21.434
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Città #
Jacksonville 1.964
Chandler 1.728
Dublin 1.422
Southend 1.002
Singapore 826
Princeton 705
Izmir 638
Dearborn 568
Nanjing 494
Cambridge 323
Wilmington 311
Beijing 288
Nanchang 200
Altamura 171
Ashburn 162
Boardman 157
Santa Clara 151
Chieti 135
Shenyang 132
Woodbridge 119
Ann Arbor 114
Hebei 93
Kraków 93
Grevenbroich 83
Tianjin 78
Jiaxing 74
Kunming 72
Changsha 68
Munich 55
Los Angeles 54
Hangzhou 51
Norwalk 51
Jinan 44
Brussels 41
Orange 39
Brno 36
Helsinki 35
Washington 35
Kocaeli 31
Hefei 28
Ningbo 28
Guangzhou 27
Lanzhou 26
Zhengzhou 26
Rome 24
San Mateo 24
Shanghai 24
Augusta 23
Houston 22
Auburn Hills 21
New York 21
Pescara 20
Leawood 18
Dong Ket 17
Seattle 17
Taizhou 17
Moscow 16
Spoltore 15
Düsseldorf 14
Romola 14
Changchun 13
Milan 13
Toronto 13
Fuzhou 12
Tavagnacco 12
Frontone 10
Hanover 10
Olomouc 10
Montesilvano 9
Ferrara 8
Tappahannock 8
Viterbo 8
Ardabil 7
Lanciano 7
Menlo Park 7
Torino 7
Falls Church 6
Frankfurt am Main 6
London 6
L’Aquila 6
Mugnano Di Napoli 6
Naples 6
Simi Valley 6
Verona 6
Walnut 6
Cape Town 5
Dubai 5
Gavirate 5
Mexico City 5
Perm 5
San Vito Chietino 5
Taiyuan 5
Avellino 4
Bari 4
Bologna 4
Cairo 4
Campobasso 4
Castellammare di Stabia 4
Chongqing 4
Haikou 4
Totale 13.360
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Nome #
“DERIVATI ISOSSAZOLICI E LORO IMPIEGO COME INIBITORI DELLA CICLOOSSIGENASI” 190
Low-dose aspirin acetylates cyclooxygenase-1 in human colorectal mucosa: implications for the chemoprevention of colorectal cancer. 123
Response to "Pharmacodynamic Interaction Between Aspirin and Ibuprofen: A Plausible Mechanism of Aspirin Resistance" 110
Reduced variability to aspirin antiplatelet effect by the coadministration of statins in high-risk patients for cardiovascular disease. 110
Reappraisal of the clinical pharmacology of low-dose aspirin by comparing novel direct and traditional indirect biomarkers of drug action 108
Aspirin prevents colorectal cancer metastasis in mice by splitting the crosstalk between platelets and tumor cells. 105
Dysregulated post-transcriptional control of COX-2 gene expression in gestational diabetic endothelial cells 101
ROLE OF DOSE POTENCY IN THE PREDICTION OF RISK OF MYOCARDIAL INFARCTION ASSOCIATED WITH NONSTEROIDAL ANTI-INFLAMMATORY DRUGS IN THE GENERAL POPULATION. 100
Nonsteroidal anti-inflammatory drugs and cardiovascular safety - translating pharmacological data into clinical readouts. 100
LA CASCATA DELL'ACIDO ARACHIDONICO 99
The biochemical selectivity of novel COX-2 inhibitors in whole blood assays of COX-isozyme activity. 98
Thromboxane biosynthesis and pulmonary function in cystic fibrosis 97
Biochemical and pharmacological characterization of the cyclooxygenase activity of human blood prostaglandin endoperoxide synthases 97
Platelet-Derived Microparticles From Obese Individuals: Characterization of Number, Size, Proteomics, and Crosstalk With Cancer and Endothelial Cells. 94
Grand challenges in pharmacotherapy of inflammation for the first decades of the 21st century. 94
Measurement of 8-iso-prostaglandin F2alpha in biological fluids as a measure of lipid peroxidation 93
Oxidative stress and platelet activation in essential hyperytension 92
Platelet-specific deletion of cyclooxygenase-1 ameliorates dextran sulfate sodium-induced colitis in mice. 92
Novel insights into the regulation of cyclooxygenase-2 expression by platelet-cancer cell cross-talk. 92
THE SELECTIVITY OF NOVEL COX-2 INHIBITORS IN HUMAN WHOLE BLOOD ASSAYS OF COX-ISOZYME ACTIVITY. 91
Effects of AF3442 [N-(9-ethyl-9H-carbazol-3-yl)-2-(trifluoromethyl)benzamide], a novel inhibitor of human microsomal prostaglandin E synthase-1, on prostanoid biosynthesis in human monocytes in vitro. 91
New insights into COX-2 biology and inhibition. 90
Mechanisms of the antitumoural effects of aspirin in the gastrointestinal tract. 90
Dysregulation of gene expression in human fetal endothelial cells from gestational diabetes in response to TGF-β1 89
Rare SNP rs12731181 in the miR-590-3p Target Site of the Prostaglandin F2α Receptor Gene Confers Risk for Essential Hypertension in the Han Chinese Population. 89
Platelets as crucial partners for tumor metastasis: from mechanistic aspects to pharmacological targeting 88
Antithrombotic Agents and Cancer 88
Platelet activation in patients with colorectal cancer. 87
ISOXAZOLE DERIVATIVES AND THEIR USE AS CYCLOOXYGENASE INHIBITORS 87
Effects of estrogen on endothelial prostanoid production and cyclooxygenase-2 and heme oxygenase-1 expression. 87
Aspirin after acute myocardial infarction: a systematic approach to compare the hemostatic effects of three different doses. 86
Low-dose naproxen interferes with the antiplatelet effects of aspirin in healthy subjects: recommendations to minimize the functional consequences 86
Pharmacodynamic of cyclooxygenase inhibitors in humans. 84
Effetto del propranololo e del suo metabolita attivo 4-OH propranololo sui prostanoidi COX-2 derivati e sull’emossigenasi-1 (OH-1) in cellule HUVEC. 84
miR-574-5p as RNA decoy for CUGBP1 stimulates human lung tumor growth by mPGES-1 induction. 84
Role of dose potency in the prediction of risk of myocardial infarction associated with nonsteroidal anti-inflammatory drugs in the general population. 84
PROSTAGLANDIN E2-MEDIATED ACTIVATION OF PHOSPHATIDYLINOSITOL 3-OH KINASE DIFFERENTIALLY AFFECTS IL-10 AND IL-1β PRODUCTION IN BLOOD CELLS. 83
The future of traditional nonsteroidal antiinflammatory drugs and cyclooxygenase-2 inhibitors in the treatment of inflammation and pain. 83
Curbing tumorigenesis and malignant progression through the pharmacological control of the wound healing process. 83
Therapeutic targeting of dysregulated cellular communication. 83
Aspirin and Cancer 83
OXIDATIVE STRESS AND PLATELET ACTIVATION IN HUMAN ESSENTIAL HYPERTENSION. 82
Aspirin, platelet inhibition and cancer prevention. 82
CYCLOOXYGENASE-2-DERIVED PROSTACYCLIN RESTRAIN PLATELET THROMBOXANE BIOSYNTHESIS IN TOLL-LIKE RECEPTOR 4 POLYMORPHISM 81
Heterogeneity in the suppression of platelet cyclooxygenase-1 activity by aspirin in coronary heart disease 81
Reduced thromboxane biosynthesis in carriers of toll-like receptor 4 polymorphisms in vivo. 80
Induction of prostacyclin by steady laminar shear stress suppresses Tumor Necrosis Factor-alfa biosyntesis via Heme Oxygenase-1 in human endothelial cells. 80
T-type channel blocking properties and antiabsence activity of two imidazo[1,2-b]pyridazine derivatives structurally related to indomethacin. 80
NCX 4040, a Nitric Oxide-Donating Aspirin, Exerts Anti-Inflammatory Effects through Inhibition of I{kappa}B-{alpha} Degradation in Human Monocytes. 80
Celecoxib, ibuprofen, and the antiplatelet effect of aspirin in patients with osteoarthritis and ischemic heart disease 79
Pharmacological inhibition of platelet-tumor cell cross-talk prevents platelet-induced overexpression of cyclooxygenase-2 in HT29 human colon carcinoma cells. 79
Synthesis, pharmacological characterization, and docking analysis of a novel family of diarylisoxazoles as highly selective cyclooxygenase-1 (COX-1) inhibitors. 79
Cyclooxygenase inhibitors: From pharmacology to clinical read-outs 79
A comparison of low-dose aspirin and dazoxiben as selective inhibitors of thromboxane A2 production in man. 78
Mechanistic and pharmacological issues of aspirin as an anticancer agent 78
Modulation of prostaglandin h synthase-2 (pghs-2) expression in human monocytes by glucocorticoids. 77
INCREASED THROMBOXANE PRODUCTION BY MONOCYTE PROSTAGLANDIN ENDOPEROXIDE SYNTHASE-2 IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION. 77
Clinical pharmacology of etoricoxib: a novel selective COX2 inhibitor. 77
HIPK2 regulates beta-catenin level and transcriptional potential 77
Platelets and extracellular vesicles in cancer: diagnostic and therapeutic implications 77
Pharmacological Characterization of the Microsomal Prostaglandin E2 Synthase-1 Inhibitor AF3485 In Vitro and In Vivo 77
Usefulness of enzimatic intermediate markers-example of cox-2 inhibition 76
A SELECTIVE THROMBOXANE-SYNTHASE INHIBITOR, ON PLATELET AND RENAL PROSTAGLANDIN ENDOPEROXIDE METABOLISM 76
INDUCTION OF PROSTACYCLIN BY STEADY LAMINAR SHEAR STRESS SUPPRESSES TUMOR NECROSIS FACTOR-ALPHA BIOSYNTHESIS VIA HEME OXYGENASE-1 IN HUMAN ENDOTHELIAL CELLS. 76
LOW-DOSE NAPROXEN INTERFERES WITH THE ANTIPLATELET EFFECT OF LOW-DOSE ASPIRIN IN HEALTHY SUBJECTS. 76
ALTERED RENAL AND PLATELET ARACHIDONIC ACID METABOLISM IN CIRRHOSIS. 76
Effects of celecoxib on prostanoid biosynthesis and circulating angiogenesis proteins in familial adenomatous polyposis. 76
Repeated exposure to codeine alters morphine glucuronidation by affecting UGT gene expression in the rat. 76
CLINICAL PHARMACOLOGY OF CYCLOOXYGENASE INHIBITION BY NAPROXEN AND LOW-DOSE ASPIRIN. 75
IN VIVO FORMATION OF 8-ISO-PROSTAGLANDIN F2α AND ASPIRIN-INSENSITIVE THROMBOXANE BIOSYNTHESIS IN UNSTABLE ANGINA. 75
Clinical pharmacology of selective COX-2 inhibitors. 75
Homeodomain-interacting protein kinase-2 restrains cytosolic phospholipase A2-dependent prostaglandin E2 generation in human colorectal cancer cells. 75
Clinical pharmacology of cyclooxygenase inhibition and pharmacodynamic interaction with aspirin by floctafenine in Thai healthy subjects. 75
Novel insights into the vasoprotective role of heme oxygenase-1. 75
Increased thromboxane production by monocyte prostaglandin endoperoxide synthase-2 in patients with acute myocardial infarction (pubbl. su Suppl. Circulation) 74
Effects of Acetaminophen on Constitutive and Inducible Prostanoid Biosynthesis in Human Blood Cells in vitro 74
RECOVERY OF THROMBOXANE BIOSYNTHESIS BY ASPIRIN-TREATED PLATELETS IN VITRO: A NOVEL MECHANISM OF ASPIRIN RESISTANCE. 74
The human pharmacology of monocyte cyclooxygenase 2 inhibition by cortisol and synthetic glucocorticoids. 74
Use of non-steroidal antiinflammatory drugs and type-specific risk of acute coronary syndrome. 73
Mechanistic aspects of COX-2 expression in colorectal neoplasia. 73
A double-blind randomized study of the anti-platelet effects of low-dose ASA and placebo in patients after myocardial infarction 72
EFFECTS OF CELECOXIB ON SYSTEMIC MARKERS OF PROSTANOID GENERATION AND INFLAMMATION AND ANGIOGENESIS IN PATIENTS WITH FAMILIAL ADENOMATOUS POLYPOSIS: A BIOMARKER CLINICAL STUDY. 72
Low dose aspirin: how low, how often? 72
THE ROLE OF ARACHIDONIC ACID METABOLITE PGE2 ON T CELL PROLIFERATIVE RESPONSE. 72
Cardiovascular effects of valdecoxib: transducing human pharmacology results into clinical read-outs. 72
Pharmacodynamic interaction of naproxen with low-dose aspirin in healthy subjects 72
In vitro morphine metabolism by rat microglia. 72
Gut microbiota, host gene expression, and aging. 72
P2Y12 Receptors in Tumorigenesis and Metastasis 72
LOW-DOSE ASPIRIN IS A SELECTIVE INHIBITOR OF THROMBOXANE-RELATED PLATELET FUNCTION IN PATIENTS WITH MYOCARDIAL INFARCTION. 71
BIOCHEMICAL AND PHARMACOLOGICAL CHARACTERIZATION OF CYCLOOXYGENASE ACTIVITY OF HUMAN BLOOD PROSTAGLANDIN ENDOPEROXIDE SYNTHASES. 71
INIBITORI SELETTIVI DI COX-2: LE NUOVE MOLECOLE 71
Platelet-activating factor (PAF) receptor antagonists inhibit mitogen-induced human peripheral blood T-cell proliferation 71
NSAIDs and cardiovascular disease: transducing human pharmacology results into clinical read-outs in the general population. 71
A class of pyrrole derivatives endowed with analgesic/anti-inflammatory activity. 71
Platelets, cyclooxygenases, and colon cancer. 71
FARMACI ANTIINFIAMMATORI NON STEROIDEI 70
Induction of prostaglandin endoperoxide synthase 2 in monocytes of human whole blood is associated with cyclooxigenase-dependent isoprostane formation 70
ANTIINFLAMMATORY COMPOUNDS L-745,337 AND NS-398 ARE SELECTIVE INHIBITORS OF PROSTAGLANDIN ENDOPEROXIDE SYNTHASE-2 IN HUMAN BLOOD MONOCYTES 70
DIFFERENTIAL CONTRIBUTION OF CYCLOOXYGENASE-ISOZYMES TO THE GENERATION OF PROSTACYCLIN AND PROSTAGLANDIN E2 BY ENDOTHELIAL CELLS IN RESPONSE TO STEADY LAMINAR SHEAR STRESSS. 70
Totale 8.324
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Categoria #
all - tutte 89.059
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 89.059
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.769 0 0 0 0 0 0 581 484 120 162 406 16
2020/20212.195 343 3 340 13 236 427 48 42 170 349 85 139
2021/20221.264 12 16 38 202 122 9 25 103 123 25 192 397
2022/20234.632 374 433 179 589 495 970 291 409 626 55 90 121
2023/20241.827 163 100 131 53 100 456 496 36 7 35 17 233
2024/20251.907 368 638 539 105 104 152 1 0 0 0 0 0
Totale 22.274