IRIS
PATRIGNANI, Paola
 Distribuzione geografica
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Continente #
NA - Nord America 11.535
EU - Europa 8.909
AS - Asia 7.904
SA - Sud America 1.077
AF - Africa 109
Continente sconosciuto - Info sul continente non disponibili 25
OC - Oceania 13
Totale 29.572
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Nazione #
US - Stati Uniti d'America 11.336
CN - Cina 2.832
SG - Singapore 2.793
UA - Ucraina 1.825
IE - Irlanda 1.432
GB - Regno Unito 1.298
TR - Turchia 1.241
IT - Italia 939
BR - Brasile 914
SE - Svezia 904
FR - Francia 815
DE - Germania 621
FI - Finlandia 374
RU - Federazione Russa 324
VN - Vietnam 323
IN - India 270
PL - Polonia 148
CA - Canada 102
HK - Hong Kong 78
AR - Argentina 71
MX - Messico 71
KR - Corea 54
BD - Bangladesh 51
ZA - Sudafrica 50
CZ - Repubblica Ceca 47
BE - Belgio 45
JP - Giappone 45
ES - Italia 40
SA - Arabia Saudita 33
IQ - Iraq 30
NL - Olanda 25
EC - Ecuador 24
ID - Indonesia 24
EU - Europa 21
AT - Austria 19
CO - Colombia 19
IL - Israele 18
LT - Lituania 17
MA - Marocco 16
IR - Iran 15
AE - Emirati Arabi Uniti 14
PK - Pakistan 13
PY - Paraguay 13
EG - Egitto 12
UZ - Uzbekistan 12
AU - Australia 11
VE - Venezuela 11
DZ - Algeria 9
CL - Cile 8
PE - Perù 8
AZ - Azerbaigian 7
GR - Grecia 6
HN - Honduras 6
JO - Giordania 6
BY - Bielorussia 5
KE - Kenya 5
LY - Libia 5
MY - Malesia 5
OM - Oman 5
PS - Palestinian Territory 5
RO - Romania 5
UY - Uruguay 5
AL - Albania 4
JM - Giamaica 4
AM - Armenia 3
BB - Barbados 3
BO - Bolivia 3
KW - Kuwait 3
LB - Libano 3
NP - Nepal 3
PA - Panama 3
PH - Filippine 3
TH - Thailandia 3
TN - Tunisia 3
TT - Trinidad e Tobago 3
XK - ???statistics.table.value.countryCode.XK??? 3
BA - Bosnia-Erzegovina 2
BH - Bahrain 2
BN - Brunei Darussalam 2
CG - Congo 2
CH - Svizzera 2
DO - Repubblica Dominicana 2
HR - Croazia 2
KZ - Kazakistan 2
LK - Sri Lanka 2
MN - Mongolia 2
NG - Nigeria 2
NO - Norvegia 2
NZ - Nuova Zelanda 2
PT - Portogallo 2
SN - Senegal 2
TW - Taiwan 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BG - Bulgaria 1
CR - Costa Rica 1
DM - Dominica 1
EE - Estonia 1
ET - Etiopia 1
GA - Gabon 1
GT - Guatemala 1
Totale 29.564
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Città #
Jacksonville 1.967
Singapore 1.960
Chandler 1.728
Dublin 1.422
Southend 1.002
Princeton 705
Dallas 695
Izmir 638
Beijing 584
Dearborn 568
Ashburn 532
Nanjing 494
Cambridge 324
Wilmington 311
Los Angeles 308
Tongling 270
Nanchang 200
The Dalles 186
Santa Clara 181
Altamura 171
Buffalo 162
Boardman 157
Chieti 135
Shenyang 132
Woodbridge 120
New York 119
Ann Arbor 114
Ho Chi Minh City 102
Hebei 93
Kraków 93
Munich 92
São Paulo 88
Tianjin 84
Grevenbroich 83
Hanoi 79
Hong Kong 75
Jiaxing 75
Council Bluffs 74
Kunming 72
Changsha 68
Redondo Beach 61
Hangzhou 52
Hefei 52
Norwalk 51
Seoul 51
Warsaw 51
Jinan 44
Brussels 41
Brooklyn 40
Pescara 40
Chicago 39
Montreal 39
Orange 39
Houston 38
Washington 38
Denver 37
Brno 36
Helsinki 36
Johannesburg 35
Tokyo 35
Rome 34
Kocaeli 31
Orem 31
Phoenix 30
Toronto 30
Guangzhou 29
Chennai 28
Ningbo 28
Boston 27
Lanzhou 27
Seattle 27
Shanghai 26
Zhengzhou 26
Atlanta 25
Poplar 25
Rio de Janeiro 25
Augusta 24
Nuremberg 24
San Mateo 24
Belo Horizonte 23
London 23
Stockholm 23
Mexico City 22
Riyadh 22
Auburn Hills 21
Camerino 19
Moscow 19
San Francisco 19
Ankara 18
Leawood 18
Charlotte 17
Dong Ket 17
Mumbai 17
Spoltore 17
Taizhou 17
Düsseldorf 16
Manchester 16
Milan 16
Amsterdam 14
Curitiba 14
Totale 18.027
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Nome #
“DERIVATI ISOSSAZOLICI E LORO IMPIEGO COME INIBITORI DELLA CICLOOSSIGENASI” 216
Low-dose aspirin acetylates cyclooxygenase-1 in human colorectal mucosa: implications for the chemoprevention of colorectal cancer. 159
Response to "Pharmacodynamic Interaction Between Aspirin and Ibuprofen: A Plausible Mechanism of Aspirin Resistance" 144
Reappraisal of the clinical pharmacology of low-dose aspirin by comparing novel direct and traditional indirect biomarkers of drug action 140
Reduced variability to aspirin antiplatelet effect by the coadministration of statins in high-risk patients for cardiovascular disease. 140
Antithrombotic Agents and Cancer 138
The biochemical selectivity of novel COX-2 inhibitors in whole blood assays of COX-isozyme activity. 133
Aspirin prevents colorectal cancer metastasis in mice by splitting the crosstalk between platelets and tumor cells. 132
Nonsteroidal anti-inflammatory drugs and cardiovascular safety - translating pharmacological data into clinical readouts. 132
Dysregulated post-transcriptional control of COX-2 gene expression in gestational diabetic endothelial cells 130
Effects of AF3442 [N-(9-ethyl-9H-carbazol-3-yl)-2-(trifluoromethyl)benzamide], a novel inhibitor of human microsomal prostaglandin E synthase-1, on prostanoid biosynthesis in human monocytes in vitro. 129
Platelet-specific deletion of cyclooxygenase-1 ameliorates dextran sulfate sodium-induced colitis in mice. 129
ROLE OF DOSE POTENCY IN THE PREDICTION OF RISK OF MYOCARDIAL INFARCTION ASSOCIATED WITH NONSTEROIDAL ANTI-INFLAMMATORY DRUGS IN THE GENERAL POPULATION. 128
Effects of estrogen on endothelial prostanoid production and cyclooxygenase-2 and heme oxygenase-1 expression. 126
Heterogeneity in the suppression of platelet cyclooxygenase-1 activity by aspirin in coronary heart disease 125
Low-dose naproxen interferes with the antiplatelet effects of aspirin in healthy subjects: recommendations to minimize the functional consequences 124
Platelet-Derived Microparticles From Obese Individuals: Characterization of Number, Size, Proteomics, and Crosstalk With Cancer and Endothelial Cells. 124
Grand challenges in pharmacotherapy of inflammation for the first decades of the 21st century. 124
Thromboxane biosynthesis and pulmonary function in cystic fibrosis 122
miR-574-5p as RNA decoy for CUGBP1 stimulates human lung tumor growth by mPGES-1 induction. 122
LA CASCATA DELL'ACIDO ARACHIDONICO 121
Platelets as crucial partners for tumor metastasis: from mechanistic aspects to pharmacological targeting 121
Rare SNP rs12731181 in the miR-590-3p Target Site of the Prostaglandin F2α Receptor Gene Confers Risk for Essential Hypertension in the Han Chinese Population. 121
New insights into COX-2 biology and inhibition. 119
Dysregulation of gene expression in human fetal endothelial cells from gestational diabetes in response to TGF-β1 119
Biochemical and pharmacological characterization of the cyclooxygenase activity of human blood prostaglandin endoperoxide synthases 118
ALTERED RENAL AND PLATELET ARACHIDONIC ACID METABOLISM IN CIRRHOSIS. 117
Differential contribution of cycloooxygenase-isozymes to the generation of prostacyclin and prostaglandin E2 by endothelial cells in response to steady laminar shear stress 117
Novel insights into the regulation of cyclooxygenase-2 expression by platelet-cancer cell cross-talk. 117
A comparison of low-dose aspirin and dazoxiben as selective inhibitors of thromboxane A2 production in man. 116
Aspirin after acute myocardial infarction: a systematic approach to compare the hemostatic effects of three different doses. 116
Effetto del propranololo e del suo metabolita attivo 4-OH propranololo sui prostanoidi COX-2 derivati e sull’emossigenasi-1 (OH-1) in cellule HUVEC. 116
Clinical pharmacology of etoricoxib: a novel selective COX2 inhibitor. 115
Synthesis, pharmacological characterization, and docking analysis of a novel family of diarylisoxazoles as highly selective cyclooxygenase-1 (COX-1) inhibitors. 115
Measurement of 8-iso-prostaglandin F2alpha in biological fluids as a measure of lipid peroxidation 115
PROSTAGLANDIN E2-MEDIATED ACTIVATION OF PHOSPHATIDYLINOSITOL 3-OH KINASE DIFFERENTIALLY AFFECTS IL-10 AND IL-1β PRODUCTION IN BLOOD CELLS. 112
Celecoxib, ibuprofen, and the antiplatelet effect of aspirin in patients with osteoarthritis and ischemic heart disease 112
Clinical pharmacology of selective COX-2 inhibitors. 112
ISOXAZOLE DERIVATIVES AND THEIR USE AS CYCLOOXYGENASE INHIBITORS 111
Aspirin and Cancer 111
Oxidative stress and platelet activation in essential hyperytension 110
[ITALIAN CONSENSUS ON EULAR 2003 RECOMMENDATIONS FOR THE TREATMENT OF KNEE OSTEOARTHRITIS.] 110
Reduced thromboxane biosynthesis in carriers of toll-like receptor 4 polymorphisms in vivo. 110
Therapeutic targeting of dysregulated cellular communication. 110
THE SELECTIVITY OF NOVEL COX-2 INHIBITORS IN HUMAN WHOLE BLOOD ASSAYS OF COX-ISOZYME ACTIVITY. 109
Platelet activation in patients with colorectal cancer. 109
Induction of prostacyclin by steady laminar shear stress suppresses Tumor Necrosis Factor-alfa biosyntesis via Heme Oxygenase-1 in human endothelial cells. 109
A class of pyrrole derivatives endowed with analgesic/anti-inflammatory activity. 109
Modulation of prostaglandin h synthase-2 (pghs-2) expression in human monocytes by glucocorticoids. 108
T-type channel blocking properties and antiabsence activity of two imidazo[1,2-b]pyridazine derivatives structurally related to indomethacin. 108
Curbing tumorigenesis and malignant progression through the pharmacological control of the wound healing process. 108
LOW-DOSE NAPROXEN INTERFERES WITH THE ANTIPLATELET EFFECT OF LOW-DOSE ASPIRIN IN HEALTHY SUBJECTS. 107
Pharmacodynamic interaction of naproxen with low-dose aspirin in healthy subjects 107
Aspirin after acute myocardial infarction: a systematic approach to compare the hemostatic effects of three different doses. 107
AMPLIFICATION LOOPS: THROMBOXANE GENERATION. 106
Mechanisms of the antitumoural effects of aspirin in the gastrointestinal tract. 106
INIBITORI SELETTIVI DI COX-2: LE NUOVE MOLECOLE 105
Advances in NSAID development: Evolution of diclofenac products using pharmaceutical technology 105
Mechanistic and pharmacological issues of aspirin as an anticancer agent 105
A double-blind randomized study of the anti-platelet effects of low-dose ASA and placebo in patients after myocardial infarction 104
A SELECTIVE THROMBOXANE-SYNTHASE INHIBITOR, ON PLATELET AND RENAL PROSTAGLANDIN ENDOPEROXIDE METABOLISM 104
Cardiovascular effects of valdecoxib: transducing human pharmacology results into clinical read-outs. 104
Pharmacological inhibition of platelet-tumor cell cross-talk prevents platelet-induced overexpression of cyclooxygenase-2 in HT29 human colon carcinoma cells. 104
Incomplete suppression of platelet COX-1 activity associated with aspirin-resistant thromboxane biosynthesis in acute coronary syndromes 103
Gut microbiota, host gene expression, and aging. 103
Clinical pharmacology of cyclooxygenase inhibition and pharmacodynamic interaction with aspirin by floctafenine in Thai healthy subjects. 103
NCX 4040, a Nitric Oxide-Donating Aspirin, Exerts Anti-Inflammatory Effects through Inhibition of I{kappa}B-{alpha} Degradation in Human Monocytes. 103
Aspirin, platelet inhibition and cancer prevention. 103
Risk management profile of etoricoxib: An example of personalized medicine 103
Increased thromboxane production by monocyte prostaglandin endoperoxide synthase-2 in patients with acute myocardial infarction (pubbl. su Suppl. Circulation) 102
RECOVERY OF THROMBOXANE BIOSYNTHESIS BY ASPIRIN-TREATED PLATELETS IN VITRO: A NOVEL MECHANISM OF ASPIRIN RESISTANCE. 102
Clinical pharmacology of novel selective COX-2 inhibitors. 102
The future of traditional nonsteroidal antiinflammatory drugs and cyclooxygenase-2 inhibitors in the treatment of inflammation and pain. 102
Dose-dependent inhibition of platelet cyclooxygenase-1 and monocyte cyclooxygenase-2 by meloxicam in healthy subjects 102
Platelets and extracellular vesicles in cancer: diagnostic and therapeutic implications 102
CLINICAL PHARMACOLOGY OF CYCLOOXYGENASE INHIBITION BY NAPROXEN AND LOW-DOSE ASPIRIN. 101
OXIDATIVE STRESS AND PLATELET ACTIVATION IN HUMAN ESSENTIAL HYPERTENSION. 101
CYCLOOXYGENASE-2-DERIVED PROSTACYCLIN RESTRAIN PLATELET THROMBOXANE BIOSYNTHESIS IN TOLL-LIKE RECEPTOR 4 POLYMORPHISM 101
Altered release of cytochrome p450 metabolites of arachidonic acid in renovascular disease. 101
Role of dose potency in the prediction of risk of myocardial infarction associated with nonsteroidal anti-inflammatory drugs in the general population. 101
Usefulness of enzimatic intermediate markers-example of cox-2 inhibition 100
De novo synthesis of cyclooxygenase-1 counteracts the suppression of platelet thromboxane biosynthesis by aspirin. 100
Increased oxidative stress and platelet activation in patients with hypertension and renovascular disease. 100
Novel analgesic/anti-inflammatory agents: 1,5-diarylpyrrole nitrooxyalkyl ethers and related compounds as cyclooxygenase-2 inhibiting nitric oxide donors. 100
Cyclooxygenase inhibitors: From pharmacology to clinical read-outs 100
Dose- Dependent inhibition of platelet cyclooxygenase-1 and monocyte cyclooxygenase-2 by meloxicam in healthy subjects. 99
Differential suppression of thromboxane biosynthesis by indobufen and aspirin in patients with unstable angina. 99
ANTIINFLAMMATORY COMPOUNDS L-745,337 AND NS-398 ARE SELECTIVE INHIBITORS OF PROSTAGLANDIN ENDOPEROXIDE SYNTHASE-2 IN HUMAN BLOOD MONOCYTES 99
Effects of celecoxib on prostanoid biosynthesis and circulating angiogenesis proteins in familial adenomatous polyposis. 99
In vitro morphine metabolism by rat microglia. 99
Novel insights into the vasoprotective role of heme oxygenase-1. 99
Determinants of platelet activation in human essential hypertension. 99
Effects of Acetaminophen on Constitutive and Inducible Prostanoid Biosynthesis in Human Blood Cells in vitro 98
INDUCTION OF PROSTACYCLIN BY STEADY LAMINAR SHEAR STRESS SUPPRESSES TUMOR NECROSIS FACTOR-ALPHA BIOSYNTHESIS VIA HEME OXYGENASE-1 IN HUMAN ENDOTHELIAL CELLS. 98
Clinical pharmacology of etoricoxib. 98
NSAIDs and cardiovascular disease. 98
Effects of nabumetone on prostanoid biosynthesis in humans. 97
IN VIVO FORMATION OF 8-ISO-PROSTAGLANDIN F2α AND ASPIRIN-INSENSITIVE THROMBOXANE BIOSYNTHESIS IN UNSTABLE ANGINA. 97
NSAIDs and cardiovascular disease: transducing human pharmacology results into clinical read-outs in the general population. 97
Platelets, cyclooxygenases, and colon cancer. 97
Totale 11.210
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Categoria #
all - tutte 125.843
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 125.843
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.260 0 0 0 0 0 427 48 42 170 349 85 139
2021/20221.264 12 16 38 202 122 9 25 103 123 25 192 397
2022/20234.632 374 433 179 589 495 970 291 409 626 55 90 121
2023/20241.827 163 100 131 53 100 456 496 36 7 35 17 233
2024/20254.671 368 638 539 105 104 152 89 383 481 213 545 1.054
2025/20265.420 955 557 1.246 1.366 841 455 0 0 0 0 0 0
Totale 30.458