IRIS
PINNEN, Francesco Enrico
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
EU - Europa 3.503
NA - Nord America 3.418
AS - Asia 1.411
Continente sconosciuto - Info sul continente non disponibili 7
SA - Sud America 3
OC - Oceania 2
AF - Africa 1
Totale 8.345
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 3.408
CN - Cina 752
UA - Ucraina 694
IE - Irlanda 571
SE - Svezia 487
IT - Italia 477
GB - Regno Unito 466
TR - Turchia 414
FR - Francia 405
DE - Germania 205
IN - India 198
FI - Finlandia 131
IR - Iran 22
PL - Polonia 21
VN - Vietnam 18
RU - Federazione Russa 13
GR - Grecia 12
BE - Belgio 11
CA - Canada 8
EU - Europa 7
IL - Israele 5
AU - Australia 2
CL - Cile 2
ES - Italia 2
HU - Ungheria 2
KR - Corea 2
NL - Olanda 2
AR - Argentina 1
AT - Austria 1
CH - Svizzera 1
EG - Egitto 1
HR - Croazia 1
MX - Messico 1
PA - Panama 1
SM - San Marino 1
Totale 8.345
Salva come PNG Salva come JPEG
Città #
Chandler 767
Jacksonville 730
Dublin 563
Southend 394
Princeton 244
Izmir 218
Nanjing 217
Dearborn 196
Cambridge 123
Chieti 117
Beijing 107
Wilmington 101
Ashburn 98
New York 86
Nanchang 76
Boardman 67
Ann Arbor 62
Altamura 60
Shenyang 56
Woodbridge 44
Hebei 43
Kunming 38
Tianjin 36
Jiaxing 23
Norwalk 23
Changsha 21
Jinan 21
Grevenbroich 20
Ardabil 19
Dong Ket 18
Kraków 18
Los Angeles 18
Pescara 18
Hangzhou 17
Kocaeli 17
Düsseldorf 16
Rome 16
Seattle 15
Washington 15
Auburn Hills 14
Ningbo 14
Orange 14
Guangzhou 10
Helsinki 10
Leawood 10
Zhengzhou 10
Augusta 9
Brussels 9
Collecorvino 9
Houston 9
Lanzhou 8
San Mateo 8
Florence 7
Hefei 7
Taizhou 7
Changchun 6
Chicago 6
Milan 6
Mumbai 6
Teramo 6
Bari 5
Bonn 5
Falls Church 5
Fuzhou 5
Haikou 5
Shanghai 5
Simi Valley 5
Elice 4
Naples 4
Silvi 4
Andover 3
Brescia 3
Fairport 3
Monmouth Junction 3
Palermo 3
Perugia 3
Rovereto 3
Toronto 3
Trieste 3
Bangalore 2
Bussolengo 2
Cedar Knolls 2
Cepagatti 2
Chengdu 2
Dallas 2
Fairfield 2
Farindola 2
Fiume Veneto 2
Gwangsan-gu 2
Harbin 2
Ithaca 2
Jesolo 2
Legnano 2
Lissone 2
Lübeck 2
Montesilvano 2
Nantes 2
Napoli 2
Orpington 2
Orta Nova 2
Totale 5.039
Salva come PNG Salva come JPEG
Nome #
Il cofarmaco ibuprofene-glutatione quale nuovo potenziale agente anti-alzheimer 192
Pseudopeptidi bioattivi. Modificazioni della porzione gamma-glutamilica del glutatione: isosteri psi (SO2NH) dello stato di transizione e gamma-aza analoghi 100
Synthesis and evaluation of trans-2-amino-5(or 6)-chloro-6(or 5)-hydroxy-1-phenyl-2,3-dihydro-1H-indenes as dopamine receptor ligands 99
Synthesis of a novel TRH-related sulphonamido peptide 99
Sintesi di trans-2-ammino-5(o 6)-cloro-6(o 5)-idrossi-1-fenil-2,3-diidro-1H-indani quali precursori di derivati a potenziale affinità per i recettori della dopamina 93
Cofarmaci L-Dopa-antiossidanti solforati quali nuovi potenziali agenti anti-Parkinson 93
(R)-α-Lipoyl-glycyl-L-prolyl-L-glutamyl dimethyl ester codrug as a multifunctional agent with potential neuroprotective activities 93
A glutathione derivative with chelating and in vitro neuroprotective activities: synthesis, physicochemical properties, and biological evaluation. 89
Ytterbium triflate catalysed Meerwein–Ponndorf–Verley (MPV) reduction 89
2,5-Diketopiperazines as neuroprotective agents 88
Synthesis of Short Cationic Antimicrobial Peptidomimetics Containing Arginine Analogs 88
N-(tert-butilossicarbonil)-beta,beta-ciclopentil-cisteina (acetamidometil)-metil estere per la sintesi di nuovi derivati peptidomimetici 87
Synthesis and preliminary pharmacological evaluation of 2,3,4,8,13a-hexahydro-1H-benzo(5,6)cyclohepta(1,2,3-ef)(3)benzazepine-6,7-diol derivatives as dopamine receptor ligands 85
Sintesi di trans-2-ammino-1-fenil-5-fluoro-6-idrossi (e 6-fluoro-5-idrossi)-2,3-diidro-1H-indeni quali potenziali ligandi per i recettori dopaminergici 85
A novel TRH analog containing a gamma-sultam residue replacing the pyroglutamic acid 85
Synthesis and Study of L-Dopa-Glutathione Codrugs as New Anti-Parkinson Agents with Free Radical Scavenging Properties. 84
(R)-alpha-Lipoic Acid–Gly-L-Pro-L-Glu(OMe)-OMe Codrug as Multifunctional Agent for Neurodegenerative Diseases, with Antioxidant and Neuroprotective Properties 82
Synthesis and activity of fluorescent glutathione S-conjugates as novel GST inhibitors 81
Synthesis and preliminary pharmacological evaluation of trans-2-amino-5(6)-chloro-6(5)-hydroxy-1- phenyl-2,3-dihydro-1H-indenes as dopamine receptor ligands 81
sintesi ed attività di due analoghi del glutatione a conformazione ristretta 81
Synthesis and neuromodulatory effects of TRH-related peptides: inhibitory activity on catecholamine release in vitro 81
Synthesis of a novel glutathione analogue as potential inhibitor of glutathione-S-transferase 80
A novel member of the GCN5-related N-acetyltransferase superfamily from Caenorhabditis elegans preferentially catalyses the N-acetylation of thialysine (S-(2-aminoethyl)-L-cysteine) 80
Ibuprofen and glutathione conjugate as a potential therapeutic agent for treating Alzheimer's disease 80
Synthesis and activity of novel TRH analogues targeted to TRH-R2 79
N-(tert)-Butyloxycarbonyl-beta,beta-Cyclopentyl-Cysteine (Acetamidomethyl)-Methyl Ester for Synthesis of Novel Peptidomimetic Derivatives 79
GPE and GPE analogues as promising neuroprotective agents 79
N-Acetyl-L-Methionyl-L-Dopa-Methyl Ester as a dual acting drug that relieves L-Dopa-induced oxidative toxicity 78
Sintesi e conformazione di pseudopeptidi 77
Nine-membered cyclodepsitripeptide systems containing the retroisomeric sequence of ergot-peptides 76
CNS delivery of L-Dopa by a new Hybrid Glutathione-Methionine peptidomimetic prodrug 76
A Potent (R)-alpha-bis-lipoyl Derivative Containing 8-Hydroxyquinoline Scaffold: Synthesis and Biological Evaluation of Its Neuroprotective Capabilities in SH-SY5Y Human Neuroblastoma Cells 76
Transition state isosteres of the gamma-glutamyl peptide bond hydrolysis: synthesis and characterization of the psi (CH2NH) pseudopeptide analogue of glutathione 76
Evaluation of 2,3,4,8,13a hexahydro-1H-Benzo[5,6]cyclohepta-6,7-dihydroxy[1,2,3-ef][3]benzazepine derivatives as dopamine receptor ligands 75
Synthesis of (S)-5,6-dibromo-tryptophan derivatives as building blocks for peptide chemistry 75
Approaches to pseudopeptidic ergopeptines. Synthesis and molecular structure of an alfa-aza-phenylalanine-containing oxa-cyclol 74
New pharmacologic tools against Parkinson's disease: L-Dopa-antioxidant codrugs containing the methionine residue 74
Synthesis and biological evaluation of new active For-Met-Leu-Phe-OMe analogues containing para-substituted Phe residues 74
(Acyloxy)Alkoxy Moiety as Amino Acids Protecting Group for the Synthesis of (R,R)-2,7 Diaminosuberic Acid via RCM 74
The Evolution of Peptide Synthesis: From Early Days to Small Molecular Machines 74
Design and synthesis of glutathione analogues 73
Hypotaurine disproportionation reaction: identification of products 73
synthesis and biological evaluation as anti-Parkinson agent of an analogue of Glutathione-L-Dopa containing methionine in place of the cysteinil residue 73
Novel cyclic biphalin analogue with improved antinociceptive properties 73
N-acylamino derivatives related to the peptide portion of ergopeptines 72
Evaluation of rat striatal L-Dopa and DA concentration after intraperitoneal administration of L- Dopa prodrugs in liposomal formulations 72
Codrugs Linking l-Dopa and Sulfur-Containing Antioxidants: New Pharmacological Tools against Parkinson’s Disease 72
synthesis and Activity of L-Dopa-Thiol antioxidant Co-drugs and New anti-PArkinson Agents with free Radical Scavenging Properties 72
Synthesis and evaluation of new endomorphoin analogues modified at the Pro2 residue 72
Hybrid peptides endomorphin-2/DAMGO: Design, synthesis and biological evaluation 72
Peptidi ibridi endomorfina-2/DAMGO: progettazione, sinteti e valutazione biologica 72
Preparation and pharmacological characterization of trans-2-amino-5(6)-fluoro-6(5)-hydroxy-1-phenyl-2,3-dihydro-1H-indenes as D2-like dopamine receptor agonists 72
Conformationally Constrained Histidines in the Design of Peptidomimetics: Strategies for the χ-Space Control 71
Diazabicycloundecene (DBU)-mediated lactonization of carboxy-activated N-acyl-seryl-prolyl-prolines 71
Synthesis of GPE analogues as potential neuroprotective agents 71
Backbone-modified glutathione analogues 70
Synthesis and activity of the glutathione analogue gamma-(L-gamma-oxaglutamyl)-L-cysteinyl-glycine 70
Delivery Methods of Camptothecin and Its Hydrosoluble Analogue Irinotecan for Treatment of Colorectal Cancer 70
Nuovi S-coniugati del glutatione ad attività inibitoria nei confronti delle GST umane 69
Detection of levodopa, dopamine and its metabolites in rat striatum dialysates following peripheral administration of L-DOPA prodrugs by mean of HPLC-EC 69
Synthesis and activity of novel glutathione analogues containing an urethane backbone linkage 69
New potent biphalin analogues containing p-fluoro-L-phenylalanine at the 4,4′ positions and non-hydrazine linkers 69
Molecular mechanism undelying the cerebral effect of Gly-Pro-Glu tripeptide bound to L-dopa in a Parkinson's animal model 69
Approaches to pseudopeptidic ergopeptines. Part 2. Consequences of the incorporation of an alfa-azaproline residue into the oxacyclolic system 68
Synthesis and properties of (S)-isothiazolidine-1,1-dioxide-3-carboxylic acid, a new gamma-sultam analogue of pyroglutamic acid 68
Facile transformation of glutamic acid into proline residue inside a tripeptide backbone 68
Prodrug approach for increasing cellular glutathione levels 68
Endomorphin-1 stimulates norepinephrine release in rat hypothalamus. 68
Potent isozyme-selective inhibition of human glutathione S-transferase A1-1 by a novel glutathione S-conjugate 68
Biochemical properties of new synthetic carnosine analogues containing the residue of 2,3-diaminopropionic acid: the effect of N-acetylation 67
Synthesis and evaluation of new endomorphin-2 analogues containing (Z)-α,β-didehydrophenylalanine (δZPhe) residues 67
Pharmacological profile of new fluorinated analogue of Biphalin with non-hydrazide linker (AM94): an update 67
Synthesis and biological evaluation of a novel pyroglutamil-modified TRH analogue 66
Synthesis and biological activity of new inhibitors of pantetheine hydrolase 66
Antinociceptive profile of potent opioid peptide AM94, a fluorinated analogue of biphalin with non-hydrazine linker 66
Sintesi di nuove di- e tripeptidil-aldeidi quali potenziali inibitori reversibili della caspasi-3 umana 65
Proline-Glutamate Chimeras in Isopeptides. Synthesis and Biological Evaluation of Conformationally Restricted Glutathione Analogues 65
Biological active analogues of the opioid peptide Biphalin: mixed a/b3-peptides 65
A new chromogenic substrate for pantetheine hydrolase and vanin proteins 65
The cis-4-amino-l-proline residue as a scaffold for the synthesis of cyclic and linear endomorphin-2 analogues 65
Bicyclic peptides: Solution conformation and Ca++ binding of the heterodetic bicyclic decapeptide cyclo(Glu-Leu-Pro-Gly-Ser-Ile-Pro-Ala)-cyclo(Phe-Gly)’ 64
Cyclo(His-Pro) exerts anti-inflammatory effects by modulating NF-kB and Nrf2 signalling 63
Recent advances in the treatment of neurodegenerative diseases based on GSH delivery systems. 63
psi(SO2NH) transition state isosteres of peptides. Synthesis and bioactivity of sulfonamido pseudopeptides related to carnosine. 62
L-Dopa- and dopamine- (R)-α-lipoic acid conjugates as multifunctional codrugs with antioxidant properties 62
synthesis and Activity of Endomorphin-1 and 2 analogues Incorporating Azetidine-(S)-2-carboxylic acid and Azetidine-3-carboxylic acid in place of native proline 62
Long acting opioid peptides: in vitro and in vivo biological evaluation of new fluorinated analogues of Biphalin 61
Design, synthesis and evaluation of new endomorphin analogues incorporating constrained aminoacids in place of Pro2 residue 61
Synthesis and activity of endomorphin-2 and morphiceptin analogues with proline surrogates in position 2 61
Approaches to pseudopeptidic ergopeptines. Part 3. Consequences of the incorporation of an α-azaphenylalanine residue into the ergotamine oxa-cyclolic system 61
4-Amino-1,2-dithiolane-4-carboxylic acid (Adt) as Cysteine Conformationally Restricted Analogue. Synthetic Protocol for Adt Containing Peptides 60
Synthesis and activity of the glutathione analogue gamma-(L-gamma-azaglutamyl)-L-cysteinyl-glycine. 60
Synthesys and evaluation of new endomorphin analogues modified at the Pro2 residue 60
Novel chemotactic For-Met-Leu-Phe-OMe (fMLF-OMe) analogues based on Met residue replacement by 4-amino-proline scaffold: Synthesis and bioactivity 60
Progettazione, sintesi e valutazione dell' attività di analoghi ciclici e lineari dell' endomorfina 2 contenenti un residuo di 4-(2)NH2-Pro-OH (cAmp) in posizione 2 60
Structure-Activity relationships of biphalin analogs and their biological evaluation on opioid receptors 60
Ten-membered cyclotripeptides III. Synthesis and conformation of cyclo(-MebetaAla-Phe-Pro-) and cyclo(-MebetaAla-Phe-DPro-) 59
Synthesis and biological evaluation of oligopeptides with antioxidant activity useful for treatment of neurodegenerative diseases 59
SYNTHESIS OF (S)-5,6-DIBROMO-TRYPTOPHAN DERIVATIVES AS BUILDING BLOCKS FOR PEPTIDE CHEMISTRY 59
Phosphoproteomic analysis of the effect of cyclo(His-Pro) dipeptide on PC12 cells 57
Totale 7.393
Salva come PNG Salva come JPEG
Categoria #
all - tutte 26.410
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 26.410
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019279 0 0 0 0 0 0 0 0 0 18 2 259
2019/20201.723 520 123 5 71 117 162 258 165 23 123 150 6
2020/2021804 128 1 125 6 88 149 9 5 39 132 77 45
2021/2022498 18 17 2 65 91 8 14 34 45 8 59 137
2022/20232.044 135 242 121 237 217 421 113 173 267 39 46 33
2023/2024819 83 36 52 23 46 300 227 30 7 15 0 0
Totale 8.459